Results 71 to 80 of about 22,003 (134)

Exploring the Functional Role of Programmed Death‐Ligand 1 (PD‐L1) in the Castration‐Resistant Prostate Cancer Using Transcriptomic Sequencing Analysis

open access: yesCancer Medicine, Volume 14, Issue 17, September 2025.
ABSTRACT Background Prostate cancer is one of the principal malignancies threatening human health, and the development of castration resistance often constitutes a major cause of treatment failure in its management. Methods To elucidate the potential association between programmed death‐ligand 1 (PD‐L1) and castration resistance in prostate cancer, we ...
Lin Zhong   +4 more
wiley   +1 more source

lHuman cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis [PDF]

open access: yes, 2005
Effector-memory T cells expressing Fas (Apo-1/CD95) are switched to an apoptotic program by cross-linking with Fas-ligand (FasL). Consequently, tumors that express FasL can induce apoptosis of infiltrating Fas-positive T lymphocytes and subdue any ...
Biagi, E   +8 more
core  

The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer [PDF]

open access: yes, 2018
Programmed death 1 (PD-1) is a co-inhibitory receptor in the CD28/CTL-4 family, and functions as a negative regulator of the immune system. Tumor-infiltrating lymphocytes (TIL) in many epithelial cancers express PD-1, suggesting that antitumor immunity ...
Gao, F.   +5 more
core  

Therapeutic Vaccination against Cancers - A Conceptual Overview with Updates on the Immunological Approach [PDF]

open access: yes, 2015
Cancer immunotherapy has now finally made its way and entered a new era, after decades of intensive searching of a cure for the incurable. Current attentions are particularly drawn by the very promising outcomes from a series of experimental and clinical
Huang, FP
core  

Einfluss von Herztransplantation und Stammzelltransplantation auf den Interleukin-2 Spiegel im Mausmodell [PDF]

open access: yes, 2011
Die Transplantation solider Organe hat einen festen Platz in der heutigen Medizin. Trotz der bereits erstaunlichen Ergebnisse nach Organtransplantationen bleibt der Wermutstropfen der lebenslangen, nebenwirkungsreichen immunsuppressiven Therapie.
Knuth, Juergen
core  

Checkpoint inhibitors: What gastroenterologists need to know. [PDF]

open access: yes, 2018
Checkpoint inhibitors are increasingly being used in clinical practice. They can cause various gastrointestinal, hepatic and pancreatic side effects. As these side effects can be serious, appropriate management is essential.
Ahmed, Monjur
core   +1 more source

UEG Week 2025 Moderated Posters

open access: yes
United European Gastroenterology Journal, Volume 13, Issue S8, Page S189-S802, October 2025.
wiley   +1 more source

UEG Week 2025 Poster Presentations

open access: yes
United European Gastroenterology Journal, Volume 13, Issue S8, Page S803-S1476, October 2025.
wiley   +1 more source

Single mutation tunes IRF4 function and mediates B cell character to ameliorate murine lupus. [PDF]

open access: yesiScience
Xiao ZX   +12 more
europepmc   +1 more source

Natural Killer Cells in Cancer Immunotherapy [PDF]

open access: yes, 2019
Arndt MA   +15 more
core   +1 more source

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