Results 71 to 80 of about 22,003 (134)
ABSTRACT Background Prostate cancer is one of the principal malignancies threatening human health, and the development of castration resistance often constitutes a major cause of treatment failure in its management. Methods To elucidate the potential association between programmed death‐ligand 1 (PD‐L1) and castration resistance in prostate cancer, we ...
Lin Zhong +4 more
wiley +1 more source
lHuman cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis [PDF]
Effector-memory T cells expressing Fas (Apo-1/CD95) are switched to an apoptotic program by cross-linking with Fas-ligand (FasL). Consequently, tumors that express FasL can induce apoptosis of infiltrating Fas-positive T lymphocytes and subdue any ...
Biagi, E +8 more
core
The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer [PDF]
Programmed death 1 (PD-1) is a co-inhibitory receptor in the CD28/CTL-4 family, and functions as a negative regulator of the immune system. Tumor-infiltrating lymphocytes (TIL) in many epithelial cancers express PD-1, suggesting that antitumor immunity ...
Gao, F. +5 more
core
Therapeutic Vaccination against Cancers - A Conceptual Overview with Updates on the Immunological Approach [PDF]
Cancer immunotherapy has now finally made its way and entered a new era, after decades of intensive searching of a cure for the incurable. Current attentions are particularly drawn by the very promising outcomes from a series of experimental and clinical
Huang, FP
core
Einfluss von Herztransplantation und Stammzelltransplantation auf den Interleukin-2 Spiegel im Mausmodell [PDF]
Die Transplantation solider Organe hat einen festen Platz in der heutigen Medizin. Trotz der bereits erstaunlichen Ergebnisse nach Organtransplantationen bleibt der Wermutstropfen der lebenslangen, nebenwirkungsreichen immunsuppressiven Therapie.
Knuth, Juergen
core
Checkpoint inhibitors: What gastroenterologists need to know. [PDF]
Checkpoint inhibitors are increasingly being used in clinical practice. They can cause various gastrointestinal, hepatic and pancreatic side effects. As these side effects can be serious, appropriate management is essential.
Ahmed, Monjur
core +1 more source
UEG Week 2025 Moderated Posters
United European Gastroenterology Journal, Volume 13, Issue S8, Page S189-S802, October 2025.
wiley +1 more source
UEG Week 2025 Poster Presentations
United European Gastroenterology Journal, Volume 13, Issue S8, Page S803-S1476, October 2025.
wiley +1 more source
Single mutation tunes IRF4 function and mediates B cell character to ameliorate murine lupus. [PDF]
Xiao ZX +12 more
europepmc +1 more source

