Results 191 to 200 of about 9,520,801 (360)

Host Ethnicity and Virus Genotype Shape the Hepatitis B Virus-Specific T-Cell Repertoire

, 2008
Anthony T. Tan, Elisabetta Loggi, Carolina Boni, Adeline Chia, Adam J. Gehring, Konduru S. Sastry, Vera J. Goh, Paola Fisicaro, Pietro Andreoné, Christian Brander, Seng Gee Lim, Carlo Ferrari, Florian Bihl, Antonio Bertoletti   +13 more
openalex   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Polyunsaturated liposomes are antiviral against hepatitis B and C viruses and HIV by decreasing cholesterol levels in infected cells

, 2010
Stephanie Pollock, Norica Nichita, Annette Isabel Böhmer, Cristina Radulescu, Raymond A. Dwek, Nicole Zitzmann   +5 more
openalex   +2 more sources

Complement activation by malignant B cells from patients with chronic lymphocytic leukaemia (CLL) [PDF]

, 1995
Hanne Vibeke Marquart, K GrØNbÆEk, B. Egelund Christensen, S.‐E. SVEHAG, R. G. Q. Leslie   +4 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Unveiling the B-cell conundrum in in-stent restenosis. [PDF]

Int J Cardiol Cardiovasc Risk Prev
Deng Z, Ma B.
europepmc   +1 more source

Targeting B-cells in lupus nephritis: should cautious optimism remain? [PDF]

, 2012
Brad H. Rovin
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Inhibition of autoantigen-induced B-cell receptor (BCR) internalization as a therapeutic strategy in diffuse large B cell lymphoma (DLBCL). [PDF]

Cell Death Dis
Górniak P, Polak A, Rams A, Kupcova K, Głodkowska-Mrówka E, Pilch Z, Miączyńska M, Nowis D, Gołąb J, Davis RE, Havranek O, Juszczyński P.   +11 more
europepmc   +1 more source

Flavonoids targeting of IκB phosphorylation abrogates carcinogen-induced MMP-9 and COX-2 expression in human brain endothelial cells

, 2011
Borhane Annabi, Elizabeth Tahanian, Luis Arguello Sanchez, Tze Chieh Shiao, René Roy   +4 more
openalex   +2 more sources