Results 261 to 270 of about 9,526,180 (306)

Biphasic control of the B cell transcriptome by mTORC1 and GSK3. [PDF]

Cell Rep
Kalchschmidt J, Kanno T, Park S, Dubois WD, Zhao Y, Trzaskoma P, Thomas CJ, Staudt LM, O'Shea JJ, Jung S, Casellas R.   +10 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Alternative splicing patterns in genetic subtypes of diffuse large B-cell lymphoma. [PDF]

BMC Cancer
An S, Hong J, Shin DY, Byun JM, Koh Y, Yoon SS.   +5 more
europepmc   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Lineage Switch of Adult B-Cell Acute Lymphoblastic Leukaemia to Acute Myeloid Leukaemia Following B-Cell-Directed Therapy. [PDF]

Eur J Case Rep Intern Med
Borja-Montes OF, Horton DD, Toro-Pedroza A, Escobar-Gil T, Babu D, Foucar C, Ebaid A.   +6 more
europepmc   +1 more source

ELUCIDATING REGULATORY NETWORKS PROMOTING B-CELL DEVELOPMENT

, 2012
Eva Welinder
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

FIP200 regulates plasma B cell differentiation via mitochondrial and heme homeostasis. [PDF]

J Exp Med
Xu L, Bottermann M, Villavicencio PM, Warner J, Weldon SR, Xie Z, Filby A, Liu X, Ganley IG, Ringel AE, Nair U, Batista FD.   +11 more
europepmc   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Aberrant B cell responses as drivers of autoantibody generation and epitope diversification in SLE pathogenesis. [PDF]

Front Immunol
Tariq F, Charavanmuttu Y, Labiba K, Wincup C.   +3 more
europepmc   +1 more source