Results 271 to 280 of about 9,526,180 (306)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

HMGB1 couples LEF1 to regulate B cell immunity. [PDF]

JCI Insight
Chen Q, Zhang Z, Xiang N, Luo L, Dai X, Kang D, Yang L, Zhu Y, Chang J, Jing Y, Li N, Chen Q, Jiang P, Liu J, Huang Y, Miller H, Zhou X, Zheng F, Gong Q, Liu C.   +19 more
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Dynamics of B-cell response in MERS-CoV patients and survivors with hybrid immunity. [PDF]

mBio
Al-Khatib HA, Ali FH, Zedan HT, Smatti MK, Coyle PV, Taleb SA, Hssain AA, Al-Thani AA, Yassine HM.   +8 more
europepmc   +1 more source

When the Heart Is the Target: Case of Primary Pericardial Diffuse Large B-Cell Lymphoma Presenting With Tamponade. [PDF]

Case Rep Oncol Med
Bawwab A, Khatib L, Albliwi MAS, Yang L, Zhao PJ.   +4 more
europepmc   +1 more source

Deciphering B Cell Heterogeneity and Pathogenic Mechanisms in Osteoporosis Through Single-Cell RNA Sequencing. [PDF]

Biomed Res Int
Zhou T, Zheng J, Sun Y, Wu J, Liu W, Zheng Z, Li J, Fu G, Zhang F, Chen Y, Zeng G, Song W.   +11 more
europepmc   +1 more source

The tropomyosin 3.1/3.2 inhibitor ATM-3507 alters B-cell actin dynamics and impairs the growth and motility of diffuse large B-cell lymphoma cell lines. [PDF]

Front Immunol
Bedi A, Choi K, Iskierski A, Gold MR.
europepmc   +1 more source

Prognostic outcome of extranodal marginal zone B-cell lymphoma: a nationwide cohort. [PDF]

Sci Rep
Nam SY, Jo J.
europepmc   +1 more source

A Validated Scoring Model to Predict the Relapse in the Central Nervous System of Pediatric Acute B-Cell Lymphoblastic Leukemia

Jiacheng Li, Tao Yu, Wenjing Shu, Yali Shen, Xianhao Wen, Yuxia Guo, Xianmin Guan, Jie Yu, Hua You   +8 more
openalex   +1 more source