Results 151 to 160 of about 4,351,772 (298)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Can Double-Negative B Cells and Marginal Zone B Cells Have a Potential Impact on the Outcome of Kidney Transplantation? [PDF]

open access: yesJ Clin Med
Fouza A   +8 more
europepmc   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Early-life homeostatic differentiation of thymus-resident B cells into memory B cells. [PDF]

open access: yesFront Immunol
Castañeda J   +6 more
europepmc   +1 more source

Cell cycle analysis of F'lac replication in Escherichia coli B/r [PDF]

open access: bronze, 1977
Martin S. Finkelstein   +1 more
openalex   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

NFATc1 deficiency in B cells ameliorates atopic dermatitis. [PDF]

open access: yesSci Rep
Kader HA   +11 more
europepmc   +1 more source

A Human Leukemia Cell with Both B and T Cell Surface Receptors [PDF]

open access: green, 1974
Ethan M. Shevach   +4 more
openalex   +1 more source

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