Results 171 to 180 of about 4,576,202 (266)

Tumor infiltrating B cells and tertiary lymphoid structures in pancreatic cancer prognosis and therapy. [PDF]

iScience
Pan Z, Zhang F, Zhang C, Li X, Ma Y, Yang Y, Tian X.   +6 more
europepmc   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The Role of B Cells and Antibodies in Eosinophilic Esophagitis. [PDF]

Inflamm Intest Dis
Bel Imam M, Du H, Ardicli Ö, Meinema J, van de Veen W.   +4 more
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

IgD in nucleus of pro-B cells promotes pro-B cells proliferation by regulating E2F3 expression. [PDF]

Cell Biosci
Zhang Y, Hou Y, Yu M, Zhang X, Zhang S, Zhu Z, Xu W, Huang J, Qiu X.   +8 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Single-cell transcriptomic landscape of intrahepatic B Cells in MASH. [PDF]

BMC Gastroenterol
Lu JC, Xiong ML, Cai ZQ, Mao T, Tang L, Li HY, Xu MY, Luo SZ.   +7 more
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

A stromal platform for robust expansion of functional IL-10-producing B cells for immune regulation. [PDF]

JCI Insight
Kawakami R, Imabayashi K, Baba A, Saito Y, Kawata K, Yada Y, Shibata A, Ito R, Kurasawa R, Higuchi R, Park S, Niiro H, Tanaka S, Baba Y.   +13 more
europepmc   +1 more source