Results 171 to 180 of about 4,351,772 (298)

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

B Cells as a Host of Persistent Salmonella Typhimurium. [PDF]

Immunology
Cruz-Cruz AD, Pérez-Lara JC, Velázquez DZ, Hernández-Galicia G, Ortiz-Navarrete V.   +4 more
europepmc   +1 more source

B Lymphocyte Differentiation from Fetal Liver Stem Cells In89 Sr-Treated Mice [PDF]

, 1975
Paul W. Kincade, Malcolm A.S. Moore, Robert Schlegel, J. Pye   +3 more
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Polyclonal B cells acquire LCMV antigens in a GP1-dependent manner. [PDF]

PLoS Pathog
Chamberlain G, Lopez GL, Bourguignon L, Laulhé X, Adda-Bouchard Y, Charpentier T, Honce R, Botten JW, Lamarre A.   +8 more
europepmc   +1 more source

Proceedings: B and T cells in canine lymphosarcoma [PDF]

, 1975
David Onions
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

CD27 on IgD-CD38-B Cells Mediates the Coprococcus-COPD Link. [PDF]

Int J Chron Obstruct Pulmon Dis
Gao Y, Chen L, Zhang J, Wen Z.
europepmc   +1 more source

A Correlation Between Nuclear Diameters of Oral Epithelial Squamous Cells and Blood Vitamin B₁₂ Levels of Children with Nutritional Dystrophy

, 1960
Hiromichi Oyake, Zenichiro Kudo, Tsuneo Arakawa   +2 more
openalex   +2 more sources

INDUCTION OF GUINEA PIG B-CELL LYMPHOKINE SYNTHESIS BY MITOGENIC AND NONMITOGENIC SIGNALS TO Fc, Ig, AND C3 RECEPTORS [PDF]

, 1974
Sharon M. Wahl, G. Michael Iverson, Joost J. Oppenheim   +2 more
openalex   +1 more source