Results 211 to 220 of about 29,942,317 (406)

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Regulatory B Cells in Tumor Microenvironment. [PDF]

Curr Issues Mol Biol
Cai Z, Xie L.
europepmc   +1 more source

Clinical Features and Prognostic Significance of NOTCH1 Mutations in Diffuse Large B-Cell Lymphoma

, 2021
Zhongqi Li, Fang Yu, Wenle Ye, Liping Mao, Jiansong Huang, Yang Shao, Junrong Yan, Wenjuan Yu, Jie Jin, Jinghan Wang   +9 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Editorial: Community series in trends in neuroimmunology: cross-talk between brain-resident and peripheral immune cells in both health and disease, volume II

Frontiers in Immunology
Suryanarayan Biswal, Janina E. Borgonovo, Carlos L. Freites, Verónica Martínez-Cerdeño, Rajnikant Mishra, Shashank K. Maurya, Estela M. Muñoz   +6 more
doaj   +1 more source

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review). [PDF]

Int J Mol Med
Li Y, Gong Y, Zhao J, Ran R.
europepmc   +1 more source

Clinical characteristics and outcomes of patients with diffuse large B cell lymphoma treated with R-CHOP-like or CHOP-like regimens: an 8-year experience from a single center [PDF]

, 2020
Haobo Huang, Liping Fan, Danhui Fu, Qiuyan Lin, Jianzhen Shen   +4 more
openalex   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Importance of B cells (Review). [PDF]

Int J Mol Med
Liu Z, Dai H, Cui X, Liu Y, Dong Z.
europepmc   +1 more source

Netrin-1 inducing antiapoptotic effect of acute myeloid leukemia cells in a concentration-dependent manner through the Unc-5 netrin receptor B-focal adhesion kinase axis

, 2023
Kai-Nan Zhang, Xizhou An, Yao Zhu, Lan Huang, Xinyuan Yao, Xing Zeng, Shaoyan Liang, Jie Yu   +7 more
openalex   +1 more source