Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Pentanoate modulates B cells to suppress allergic contact hypersensitivity. [PDF]
Alhmoudi S +9 more
europepmc +1 more source
B-Cells and Plasmablasts as Architects of Autoimmune Disease: From Molecular Footprints to Precision Therapeutics. [PDF]
Sarrand J, Soyfoo M.
europepmc +1 more source
The Increased Secretion of Lactate Observed in Obesity and Aging Leads to the Generation of Pathogenic B Cells. [PDF]
Romero M +7 more
europepmc +1 more source
Stratification of systemic lupus erythematosus with IGHV4-34 in unswitched memory B cells. [PDF]
Ushijima TS +6 more
europepmc +1 more source
B cells in acquired aplastic anemia and the exploratory role of rituximab: considerations in pediatric and female patients. [PDF]
Pan L +5 more
europepmc +1 more source
Promoting APC function of B cells via reprogramming the fatty acid metabolism enhances anticancer immunity in metastatic ovarian cancer. [PDF]
Zhang H +17 more
europepmc +1 more source
Related searches:
B cells are an important component of adaptive immunity. They produce and secrete millions of different antibody molecules, each of which recognizes a different (foreign) antigen. The fact that humans express a very large repertoire of antibodies is due to the complex mechanism of V(D)J recombination of immunoglobulin (Ig) genes as well as other ...
Juha, Ollila, Mauno, Vihinen
openaire +4 more sources
Recent advances in studies of immune memory in mice and humans have reinforced the concept that memory B cells play a critical role in protection against repeated infections, particularly from variant viruses. Hence, insights into the development of high-quality memory B cells that can generate broadly neutralizing antibodies that bind such variants ...
Takeshi Inoue, Tomohiro Kurosaki
openaire +2 more sources
CD5 B cells and B-cell malignancies
Current Opinion in Hematology, 1999Over the past year, progress has been made in understanding of the physiology and disease associations of CD5+ (B1) B cells, although their exact role in pathogenesis remains unclear. Earlier studies on the negative function of CD5 within the B-cell receptor complex have been substantiated, and it seems likely that soon the signaling pathways used by ...
P M, Lydyard +3 more
openaire +2 more sources

