Results 201 to 210 of about 8,030,933 (262)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Pentanoate modulates B cells to suppress allergic contact hypersensitivity. [PDF]

open access: yesSci Rep
Alhmoudi S   +9 more
europepmc   +1 more source

The Increased Secretion of Lactate Observed in Obesity and Aging Leads to the Generation of Pathogenic B Cells. [PDF]

open access: yesEur J Immunol
Romero M   +7 more
europepmc   +1 more source

Stratification of systemic lupus erythematosus with IGHV4-34 in unswitched memory B cells. [PDF]

open access: yesRheumatology (Oxford)
Ushijima TS   +6 more
europepmc   +1 more source

Promoting APC function of B cells via reprogramming the fatty acid metabolism enhances anticancer immunity in metastatic ovarian cancer. [PDF]

open access: yesCancer Immunol Immunother
Zhang H   +17 more
europepmc   +1 more source

B cells

The International Journal of Biochemistry & Cell Biology, 2005
B cells are an important component of adaptive immunity. They produce and secrete millions of different antibody molecules, each of which recognizes a different (foreign) antigen. The fact that humans express a very large repertoire of antibodies is due to the complex mechanism of V(D)J recombination of immunoglobulin (Ig) genes as well as other ...
Juha, Ollila, Mauno, Vihinen
openaire   +4 more sources

Memory B cells

Nature Reviews Immunology, 2023
Recent advances in studies of immune memory in mice and humans have reinforced the concept that memory B cells play a critical role in protection against repeated infections, particularly from variant viruses. Hence, insights into the development of high-quality memory B cells that can generate broadly neutralizing antibodies that bind such variants ...
Takeshi Inoue, Tomohiro Kurosaki
openaire   +2 more sources

CD5 B cells and B-cell malignancies

Current Opinion in Hematology, 1999
Over the past year, progress has been made in understanding of the physiology and disease associations of CD5+ (B1) B cells, although their exact role in pathogenesis remains unclear. Earlier studies on the negative function of CD5 within the B-cell receptor complex have been substantiated, and it seems likely that soon the signaling pathways used by ...
P M, Lydyard   +3 more
openaire   +2 more sources

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