Results 31 to 40 of about 29,942,317 (406)
Bystander B cells rapidly acquire antigen receptors from activated B cells by membrane transfer: a novel mechanism for enhancing specific antigen presentation [PDF]
, 2007 The B cell antigen receptor (BCR) efficiently facilitates the capture and processing of a specific antigen for presentation on MHC class II molecules to antigen specific CD4+ T cells (1).
Ben J. C. Quah +5 more
core +2 more sources
Blimp-1-dependent and -independent natural antibody production by B-1 and B-1-derived plasma cells. [PDF]
, 2017 Natural antibodies contribute to tissue homeostasis and protect against infections. They are secreted constitutively without external antigenic stimulation.
Baumgarth, Nicole +5 more
core +1 more source
The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas.
Physiological Research, 2001 Alloxan and streptozotocin are widely used to induce experimental diabetes in animals. The mechanism of their action in B cells of the pancreas has been intensively investigated and now is quite well understood.
T. Szkudelski
semanticscholar +1 more source
Cancer Biology & Medicine, 2021 Tertiary lymphoid structures (TLSs) are ectopic immune cell aggregations that develop in peripheral tissues in response to a wide range of chronic inflammatory conditions, including infection, autoimmune disease, and cancer. In the tumor microenvironment
Hua Zhao +3 more
doaj +1 more source
Artery tertiary lymphoid organs control multi-layered territorialized atherosclerosis B cell responses in aged ApoE-/- mice [PDF]
, 2016 Objective: Explore aorta B cell immunity in aged ApoE-/- mice. Approach and Results: Transcript maps, FACS, immunofluorescence analyses, cell transfers, and Ig-ELISPOT assays showed multi-layered atherosclerosis B cell responses in artery tertiary ...
Andreas J.R. Habenicht +13 more
core +1 more source
B cells and cancer: To B or not to B?
Journal of Experimental Medicine, 2020 Tertiary lymphoid structures, adjacent to tumor nests, are sites where antitumor adaptive T and B cell immune responses are generated. Fridman et al.
W. Fridman +6 more
semanticscholar +1 more source
The Journal of Immunology, 2006 AbstractCD5+ B cells have attracted considerable interest because of their association with self-reactivity, autoimmunity, and leukemia. In mice, CD5+ B cells are readily generated from fetal/neonatal precursors, but inefficiently from precursors in adult.
openaire +2 more sources
Immunological Reviews, 2020 Tumorigenesis proceeds through discrete steps where acquisition of genetic lesions and changes in the surrounding microenvironment combine to drive unrestricted neoplastic proliferation and metastasis.
D. Michaud +3 more
semanticscholar +1 more source
Integrate CRISPR/Cas9 for protein expression of HLA-B*38:68Q via precise gene editing. [PDF]
, 2019 The determination of null- or low-expressed HLA alleles is clinically relevant in both hematopoietic stem cell transplantation and solid organ transplantation.
Reed, Elaine F +2 more
core +1 more source
Clinical case of primary immunodeficiency: X-linked agammaglobulinemia
Медицинская иммунология, 2020 Aclinical case ofprimary immunodeficiency state (PIDS) is described: X-linked agammaglobulinemia in the boy of 8 years old. The results of molecular genetic studies: gene btk (ex 1-19) genome version GRCh38.p5, transcript version ENST00000308731 single ...
E. V. Kuvschinova +4 more
doaj +1 more source