Results 51 to 60 of about 8,044,473 (306)
Pediatric Blood &Cancer, EarlyView.Abstract Background Sickle cell disease (SCD) is an autosomal recessive hemoglobinopathy affecting millions of individuals worldwide. The clinical expression and psychosocial burden of SCD vary widely across geographical, cultural, and healthcare system contexts, underscoring the need for setting‐specific approaches to assessment.
Desiré Fantasia +7 more
wiley +1 more source
Features of B cell subsets in primary Sjogren’s syndrome and systemic lupus erythematosus
Научно-практическая ревматологияBackground. Lymphocyte subsets in autoimmune diseases, such as systemic lupus erythematosus (SLE) and primary Sjogren’s syndrome (pSS), have been intensively studied in recent years.
S. S. Benevolenskaya +13 more
doaj +1 more source
Adaptive immunity in the joint of rheumatoid arthritis
Immunological Medicine, 2022 Adaptive immunity plays central roles in the pathogenesis of rheumatoid arthritis (RA), as it is regarded as an autoimmune disease. Clinical investigations revealed infiltrations of B cells in the synovium, especially those with ectopic lymphoid ...
Hisakata Yamada
doaj +1 more source
Современная ревматология, 2022 In the last decade, anti-neutrophil cytoplasmic antibodies (ANCA)-associated systemic vasculitis (SV) has been treated with the anti-B-cell drug, rituximab (RTM) both for induction and maintenance therapy. One of the problems of the treatment with RTM in
T. V. Beketova +2 more
doaj +1 more source
Reversion of anergy signatures in clonal CD21low B cells of mixed cryoglobulinemia after clearance of HCV viremia. [PDF]
, 2017 Hepatitis C virus (HCV) causes mixed cryoglobulinemia (MC) by driving clonal expansion of IgM+CD27+ B cells. These cells display both the features of anergy induced by continual engagement of the B cell receptor (BCR), such as high expression of ...
Casato, Milvia +7 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij +11 more
wiley +1 more source
Functionality of the human antibody response to Candida albicans
Virulence, 2021 Candida albicans is a common commensal on human mucosal surfaces, but can become pathogenic, e.g. if the host is immunocompromised. While neutrophils, macrophages and T cells are regarded as major players in the defense against pathogenic C.
Melissa Wich +8 more
doaj +1 more source
Expression of interleukin 2 receptors on activated human B cells. [PDF]
, 1984 Using anti-Tac, a monoclonal anti-interleukin 2 (IL-2) receptor antibody, we have explored the possibility that certain activated B cells display receptors for IL-2.
Bongiovanni, KF +8 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Chemotherapy‐induced peripheral neuropathy remains a major complication in pediatric cancer, with disrupted somatosensory and nociceptive processing being a key aspect. This review synthesizes empirical studies on alterations in somatosensory and nociceptive processing in children and adolescents with cancer.
Julia Schweiger +4 more
wiley +1 more source
Distinctive growth requirements and gene expression patterns distinguish progenitor B cells from pre-B cells. [PDF]
, 1993 Long-term bone marrow cultures have been useful in determining gene expression patterns in pre-B cells and in the identification of cytokines such as interleukin 7 (IL-7).
Faust, EA +4 more
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