Results 61 to 70 of about 26,251,282 (347)

B cells and cancer

open access: yesCancer Cell, 2021
Tumor-infiltrating B cells complement T cell-mediated antitumor immunity. A panel of experts share their views on the complexity of B cells within the tumor microenvironment, the variety of mechanisms by which these cells control tumor growth, their organization in tertiary lymphoid structures, and their association with immunotherapy response.
Engelhard, Victor   +6 more
openaire   +3 more sources

Memory B Cells of Mice and Humans.

open access: yesAnnual Review of Immunology, 2017
We comprehensively review memory B cells (MBCs), covering the definition of MBCs and their identities and subsets, how MBCs are generated, where they are localized, how they are maintained, and how they are reactivated.
Florian J. Weisel, M. Shlomchik
semanticscholar   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

B cells and atherosclerosis [PDF]

open access: yesAmerican Journal of Physiology-Heart and Circulatory Physiology, 2017
B cells have emerged as important immune cells in cardiovascular disease. Initial studies have suggested that B cells protect against atherosclerosis development. However, subsequent studies demonstrating aggravation of atherosclerosis by B-2 cells have shed light on the subset-dependent effects of B cells.
Coleen A. McNamara, Prasad Srikakulapu
openaire   +3 more sources

Targeting B Cells and Plasma Cells in Autoimmune Diseases

open access: yesFrontiers in Immunology, 2018
Success with B cell depletion using rituximab has proven the concept that B lineage cells represent a valid target for the treatment of autoimmune diseases, and has promoted the development of other B cell targeting agents.
K. Hofmann, Ann-Katrin Clauder, R. Manz
semanticscholar   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Structural Analysis of Avian Encephalomyelitis Virus Polyprotein for Development of Multi Epitopes Vaccine Using Immunoinformatics Approach

open access: yesJournal of Pure and Applied Microbiology, 2021
Avian Encephalomyelitis (AE) is the disease caused by avian encephalomyelitis virus (AEV). The disease mainly affects young birds nervous system worldwide causing high morbidity and variable mortality rate in chicks and noticed egg dropping and ...
Fatima Khalid Elhassan   +4 more
doaj   +1 more source

B Cell Immunosenescence

open access: yesAnnual Review of Cell and Developmental Biology, 2020
Innate and adaptive immune responses decline with age, leading to greater susceptibility to infectious diseases and reduced responses to vaccines. Diseases are more severe in old than in young individuals and have a greater impact on health outcomes such as morbidity, disability, and mortality.
Bonnie B. Blomberg   +4 more
openaire   +4 more sources

B cells and autoimmunity [PDF]

open access: yesCurrent Opinion in Immunology, 2011
There is a growing appreciation for the role for B cells in autoimmune disorders in which inflammation is driven by T cells, in addition to the well-established role for B cells in autoimmune disorders characterized by pathogenic auto-antibodies. Current information on tolerance checkpoints in B cells, B cell depletion, BAFF blockade, regulatory B ...
Annaiah Cariappa   +2 more
openaire   +2 more sources

GSK3 is a metabolic checkpoint regulator in B cells

open access: yesNature Immunology, 2016
B cells predominate in a quiescent state until an antigen is encountered, which results in rapid growth, proliferation and differentiation of the B cells.
J. Jellusova   +10 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy