Results 111 to 120 of about 36,341 (274)
Leg Sympathetic Response to Noxious Skin Stimuli is Similar in High and Low Level Human Spinal Cord Injury [PDF]
, 2008 Objective To determine if sympathetically mediated vasoconstriction in the lower extremities is injury level dependent. Although sympathetic responses have been measured in the limbs of people with high and low level SCI using blood flow measurements ...
Garrison, M. Kevin +2 more
core +1 more source
Journal of Sleep Research, EarlyView.ABSTRACT This prospective multi‐method study was performed to assess the feasibility and validity of an unattended home‐based sleep screening test (HBSST) in the detection of sleep‐related breathing disorders (SRBDs) among individuals with spinal cord injury (SCI).
Julio C. Furlan +6 more
wiley +1 more source
Research in Pharmaceutical Sciences, 2017 Memory impairment is one of the greatest concerns when it comes to long-term CNS-affecting drug administration. Drugs like gabapentin, pregabalin and baclofen are administered in a long-term period in conditions such as epilepsy, neuropathic pain ...
Asma Salimzade +2 more
doaj +1 more source
An autocrine role for pituitary GABA: Activation of GABA-B receptors and regulation of growth hormone levels [PDF]
, 2002 There is increasing evidence suggesting that the neurotransmitter gamma-aminobutyric acid (GABA) is a local factor involved in the regulation of endocrine organs.
Corsi, C. +5 more
core +1 more source
Flexor Reflex Decreases during Sympathetic Stimulation in Chronic Human Spinal Cord Injury [PDF]
, 2009 A better understanding of autonomic influence on motor reflex pathways in spinal cord injury is important to the clinical management of autonomic dysreflexia and spasticity in spinal cord injured patients.
Garrison, Mark Kevin, Schmit, Brian D.
core +2 more sources
Current and Future Issues in the Development of Spinal Agents for the Management of Pain. [PDF]
, 2017 Targeting analgesic drugs for spinal delivery reflects the fact that while the conscious experience of pain is mediated supraspinally, input initiated by high intensity stimuli, tissue injury and/or nerve injury is encoded at the level of the spinal ...
Fisher, Casey J +3 more
core +2 more sources
Experimental Physiology, EarlyView.Abstract Chronic visceral pain is a key symptom of irritable bowel syndrome. Modulation of voltage‐gated calcium and potassium channels by G protein‐coupled receptors plays a key role in dampening nociceptive transmission. Both baclofen and the analgesic peptide α‐conotoxin Vc1.1 activate GABAB receptors (GABABR), resulting in inhibition of CaV2.2 and ...
Mariana Brizuela +4 more
wiley +1 more source
Treatment of recalcitrant cough with baclofen
Italian Journal of Medicine, 2013 Background: Chronic dry cough is a debilitating symptom often refractory to standard antitussive therapy. It may result from increased sensitivity of the cough reflex. Baclofen, an agonist of gamma-aminobutyric acid (GABA), has been shown, in animals, to
Paolo Agostinis +9 more
doaj +1 more source
Histologi Dorsal Horn Dari Spinal Cord Mencit Yang Mengalami Nyeri Inflamasi Akibat Induksi Cfa (Completed Freuds Adjuvant) Setelah Pemberian Gabapentin Dan Baclofen [PDF]
, 2013 Pain is a multidimentional experience, generally most of chronic disease followed by pain incidence. Chronic pain can be caused by inflammation or neuropathic condition and change the imbalance of N-methyl-D-aspartate receptor 2B (NR2B) subunit.
Fajrin, F. A. (Fifteen) +2 more
core
The Journal of Physiology, EarlyView.Abstract figure legend With ageing and age‐related neurodegenerative diseases, the amount of GABA and GABAergic inhibition as well as the modulation (indicated by sine wave) of GABAergic inhibition is reduced, whereas excitation is increased. In many parts of the brain, this leads to a mismatch of facilitatory (green neurons) and inhibitory (red ...
Wolfgang Taube, Benedikt Lauber
wiley +1 more source