Results 111 to 120 of about 36,785 (263)

Orthopedic surgery in children with intrathecal baclofen pumps

Journal of Pediatric Rehabilitation Medicine, 2013
AIMS: Children with cerebral palsy often have severe spasticity leading to deformity that requires multiple orthopedic surgeries. Intrathecal baclofen pump implantation effectively decreases severe spasticity. The objective of this study was to determine
Judith L. Gooch, Molly McFadden, Wende Oberg   +2 more
doaj   +1 more source

A randomized, open-label, standard controlled, parallel group study of efficacy and safety of baclofen, and chlordiazepoxide in uncomplicated alcohol withdrawal syndrome

Biomedical Journal, 2016
Background: Alcohol withdrawal syndrome (AWS) is a distressing condition, generally controlled by benzodiazepines (BZD's). Baclofen, a gamma-aminobutyric acid-B (GABAB) agonist, has also shown promising results in controlling AWS.
K. Girish, K. Vikram Reddy, Lakshmi V. Pandit, H.P. Pundarikaksha, R. Vijendra, K. Vasundara, R. Manjunatha, Moulya Nagraj, R. Shruthi   +8 more
doaj   +1 more source

Distinct fos-expressing neuronal ensembles in the ventromedial prefrontal cortex mediate food reward and extinction memories [PDF]

, 2016
In operant learning, initial reward-associated memories are thought to be distinct from subsequent extinction-associated memories. Memories formed during operant learning are thought to be stored in “neuronal ensembles.” Thus, we hypothesize that ...
Bossert, Jennifer M., Caprioli, Daniele, Cruz, Fabio C., Hope, Bruce T., Leao, Rodrigo M., Mcpherson, Kylie B., Mendoza, Michael P., Rubio, F. Javier, Shaham, Yavin, Warren, Brandon L., Whitaker, Leslie R.   +10 more
core   +2 more sources

Effectiveness and safety of abobotulinumtoxinA in pediatric lower limb spasticity: A phase IV, prospective, observational, multicenter study

Developmental Medicine &Child Neurology, Volume 68, Issue 2, Page 227-239, February 2026.
Abstract Aim To assess the longitudinal attainment of patient‐centered, function‐related Goal Attainment Scaling Total (GAS T)‐score after repeated abobotulinumtoxinA (AboBoNT‐A) injections over a period of up to 30 months and up to 10 cycles. Method In this prospective observational study, the investigators' clinical practices recruited patients aged ...
Mark E. Gormley, Edward Dabrowski, Mauricio R. Delgado, Ann Tilton, Asare Christian, Sarah Helen Evans, Anne‐Sophie Grandoulier, Jumaah Goldberg   +7 more
wiley   +1 more source

GABA\u3csub\u3eB\u3c/sub\u3e Receptors Couple to Gα\u3csub\u3eq\u3c/sub\u3e to Mediate Increases in Voltage-Dependent Calcium Current During Development [PDF]

, 2015
Metabotropic GABAB receptors are known to modulate the activity of voltage-dependent calcium channels. Previously, we have shown that GABAB receptors couple to a non-Gi/o G-protein to enhance calcium influx through L-type calcium channels by activating ...
Karls, Andrew S., Mynlieff, Michelle
core   +1 more source

Outcomes of selective dorsal rhizotomy in ambulatory children and young people with cerebral palsy: A scoping review

Developmental Medicine &Child Neurology, Volume 68, Issue 2, Page 175-186, February 2026.
This scoping review highlights that in the selective dorsal rhizotomy (SDR) literature, the emphasis still remains on impairment‐based outcomes in the body function and structure domain of the ICF. However, there has been a small shift towards participation and quality‐of‐life outcomes in the last decade.
Deepti Chugh, Eleanor Main, Gillian Waite, Lucy Alderson, Kristian Aquilina, Cherry Kilbride, Tim Theologis, Hortensia Gimeno   +7 more
wiley   +1 more source

Histologi Dorsal Horn Dari Spinal Cord Mencit Yang Mengalami Nyeri Inflamasi Akibat Induksi Cfa (Completed Freuds Adjuvant) Setelah Pemberian Gabapentin Dan Baclofen [PDF]

, 2013
Pain is a multidimentional experience, generally most of chronic disease followed by pain incidence. Chronic pain can be caused by inflammation or neuropathic condition and change the imbalance of N-methyl-D-aspartate receptor 2B (NR2B) subunit.
Fajrin, F. A. (Fifteen), Khotib, J. (Junaidi), Susilo, I. (Imam)   +2 more
core  

Feasibility, Validity and Economic Impact of a Home‐Based Sleep Screening Test in the Detection of Sleep‐Related Breathing Disorders in Individuals Living With Spinal Cord Injury: A Multi‐Method Study and Cost‐Minimisation Analysis

Journal of Sleep Research, Volume 35, Issue 1, February 2026.
ABSTRACT This prospective multi‐method study was performed to assess the feasibility and validity of an unattended home‐based sleep screening test (HBSST) in the detection of sleep‐related breathing disorders (SRBDs) among individuals with spinal cord injury (SCI).
Julio C. Furlan, Julia I. Coschignano, Sarah Berger, Sander L. Hitzig, James Milligan, Peter Athanasopoulos, Mark I. Boulos   +6 more
wiley   +1 more source

Comparative effects of chronic administrations of gabapentin, pregabalin and baclofen on rat memory using object recognition test

Research in Pharmaceutical Sciences, 2017
Memory impairment is one of the greatest concerns when it comes to long-term CNS-affecting drug administration. Drugs like gabapentin, pregabalin and baclofen are administered in a long-term period in conditions such as epilepsy, neuropathic pain ...
Asma Salimzade, Ali Hosseini-Sharifabad, Mohammad Rabbani   +2 more
doaj   +1 more source

Effects of baclofen on swallow motor pattern

Frontiers in Neurology
Baclofen is a GABAB receptor agonist used clinically to manage spasticity. It has also been associated with increased duration of mechanical ventilation and rates of aspiration pneumonitis. We hypothesized that baclofen would impair pharyngeal swallow, a
Nathan W. Fielder, Michael Frazure, Ivan Poliacek, Ivan Poliacek, Donald C. Bolser, Kimberly E. Iceman, Teresa Pitts   +6 more
doaj   +1 more source