Results 1 to 10 of about 92,119 (95)
Identification and characterization of the Hfq bacterial amyloid region DNA interactions [PDF]
BBA Advances, 2021 Nucleic acid amyloid proteins interactions have been observed in the past few years. These interactions often promote protein aggregation. Nevertheless, molecular basis and physiological consequences of these interactions are still poorly understood ...
Florian Turbant +6 more
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Accelerated Amyloid Beta Pathogenesis by Bacterial Amyloid FapC [PDF]
Advanced Science, 2020 The gut–brain axis has attracted increasing attention in recent years, fueled by accumulating symptomatic, physiological, and pathological findings. In this study, the aggregation and toxicity of amyloid beta (Aβ), the pathogenic peptide associated with ...
Ibrahim Javed +10 more
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In Situ Characterization of Hfq Bacterial Amyloid: A Fourier-Transform Infrared Spectroscopy Study [PDF]
Pathogens, 2019 Hfq is a bacterial protein that regulates gene expression at the post-transcriptional level in Gram-negative bacteria. We have previously shown that Escherichia coli Hfq protein, and more precisely its C-terminal region (CTR), self-assembles into an ...
David Partouche +5 more
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Functional bacterial amyloid increases Pseudomonas biofilm hydrophobicity and stiffness [PDF]
Frontiers in Microbiology, 2015 The success of Pseudomonas species as opportunistic pathogens derives in great part from their ability to form stable biofilms that offer protection against chemical and mechanical attack.
Guanghong eZeng +8 more
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Amyloid β-peptide multimer expressed in green algae efficiently inhibits bacteria growth by disrupting cell membrane permeability [PDF]
Scientific ReportsAmyloid β-peptide, traditionally associated with Alzheimer’s disease pathology, has recently been identified as a potential antimicrobial peptide (AMP) with broad-spectrum antibacterial activity.
Ying-Ying Hu +3 more
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Molecules, 2022 Functional amyloid is produced by many organisms but is particularly well understood in bacteria, where proteins such as CsgA (E. coli) and FapC (Pseudomonas) are assembled as functional bacterial amyloid (FuBA) on the cell surface in a carefully ...
Thorbjørn Vincent Sønderby +2 more
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QRB Discovery, 2022 Interactions between proteins and single-stranded DNA (ssDNA) are crucial for many fundamental biological processes, including DNA replication and genetic recombination.
Krzysztof Kubiak +10 more
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The Amyloid Region of Hfq Riboregulator Promotes DsrA:rpoS RNAs Annealing
Biology, 2021 Hfq is a bacterial RNA chaperone which promotes the pairing of small noncoding RNAs to target mRNAs, allowing post-transcriptional regulation. This RNA annealing activity has been attributed for years to the N-terminal region of the protein that forms a ...
Florian Turbant +3 more
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Apomorphine Targets the Pleiotropic Bacterial Regulator Hfq
Antibiotics, 2021 Hfq is a bacterial regulator with key roles in gene expression. The protein notably regulates translation efficiency and RNA decay in Gram-negative bacteria, thanks to its binding to small regulatory noncoding RNAs. This property is of primary importance
Florian Turbant +6 more
doaj +1 more source
BBA Advances, 2022 Functional amyloids (FA) are proteins which are evolutionarily optimized to form highly stable fibrillar structures that strengthen the bacterial biofilm matrix. FA such as CsgA (E. coli) and FapC (Pseudomonas) are secreted to the bacterial surface where
Zahra Najarzadeh +6 more
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