Results 111 to 120 of about 1,155,621 (272)

Molecular-level insights into the surface-induced assembly of functional bacterial amyloid. [PDF]

Biophys J, 2022
Sønderby TV, Zou Y, Wang P, Wang C, Otzen DE.   +4 more
europepmc   +1 more source

Exploring the sequence–structure relationship for amyloid peptides [PDF]

, 2012
Amyloid fibril formation is associated with misfolding diseases, as well as fulfilling a functional role. The cross-β molecular architecture has been reported in increasing numbers of amyloid-like fibrillar systems. The Waltz algorithm is able to predict
Morris, Kyle L., Rousseau, F. (Frederic), Maya Debulpaep (16158989), Rodger, Alison, Frederic Rousseau (5872), Schymkowitz, Joost, Joost Schymkowitz (5868), Serpell, Louise C., Matthew R Hicks (16064381), Louise Serpell (4461124), Rousseau, Frederic, Hicks, Matthew R., Kyle L Morris (9164846), Alison Rodger (282425), Debulpaep, Maya   +14 more
core   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

BACTERIAL AMYLOID IN CYSTIC FIBROSIS [PDF]

Chest, 2020
T. Lazareva, G. Tetz, M. Vecherkovskaya, C. Kardava, N. Artemenko, T. Gembitskaya, V. Tetz   +6 more
openaire   +1 more source

Beyond antimicrobials: Ecological nano‐strategies for rebalancing dysbiotic oral microbial homeostasis

BMEMat, EarlyView.
Oral microbial homeostasis, a dynamic host‐microbe balance, is vital in infectious diseases. Conventional antibiotics often disrupt this homeostasis, spurring interest in nanomaterials for oral microbial homeostasis rebalancing. This review outlines nanomaterial strategies across three ecological levels (population/community, ecosystem, and cross ...
Chen Hu, Aohan Luan, Yujun Yang, Linlin Wang, Huilin Wang, Ning Wang, Guixin He, Yajie Yang, Rabiya Noor, Jawad Hussain, Longquan Shao   +10 more
wiley   +1 more source

Systemic exposure to bacterial amyloid curli alters the gut mucosal immune response and the microbiome, exacerbating <i>Salmonella</i>-induced arthritis. [PDF]

Gut Microbes, 2023
Bessho S, Grando KCM, Kyrylchuk K, Miller A, Klein-Szanto AJ, Zhu W, Gallucci S, Tam V, Tükel Ç.   +8 more
europepmc   +1 more source

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

, 2015
Item does not contain fulltextIMPORTANCE: Cerebral amyloid-beta aggregation is an early pathological event in Alzheimer disease (AD), starting decades before dementia onset. Estimates of the prevalence of amyloid pathology in persons without dementia are
Fagan, A.M., Madsen, K., Prabhakar, S., Alcolea, D., Ramakers, I.H., Nordberg, A., Spiru, L., Waldemar, G., Alexander, M., Scheltens, P., Drzezga, A., Zboch, M., Leon, M., Freund-Levi, Y., Herukka, S.K., Hellwig, S., Kohler, S., Sarazin, M., Chetelat, G., Rodriguez-Rodriguez, E., Aalten, P., Ivanoiu, A., Johannsen, P., Teunissen, C.E., Forster, S., Novak, G.P., Blennow, K., Sanchez-Juan, P., Verhey, F.R.J., van Buchem, M.A., Gkatzima, O., Klunk, W.E., Meulenbroek, O., Mroczko, B., Verhey, F.R., Almdahl, I.S., Bibeau, K., Fladby, T., Møllergård, H.M., Struyfs, H., Vos, S.J., Schütte, C., Camus, V., Lleo, A., Frederiksen, K.S., van der Flier, W.M., Baldeiras, I., Hildebrandt, H., Chen, K., Froelich, L., Koglin, N., Lisetti, V., Gordon, M.F., Rowe, C.C., Foskett, N., Meulenbroek, O.V., Kornhuber, J., Mollergard, H.M., Cavedo, E., Gill, K.D., Rodrigue, K.M., Scheltens, P.J., Aarsland, D., Newberg, A., Wolk, D.A., Hampel, H., Roe, C.M., Vandenberghe, R., Parnetti, L., Peters, O., Verbeek, M.M., Tijms, B.M., Ishihara, L., Kramberger, M.G., Mintun, M.A., Rot, U., Zetterberg, H., Villemagne, V.L., Mattsson, N., Morris, J.C., Soininen, H., Mussele, S. Van der, Laere, K. Van, Brooks, D.J., Ossenkoppele, R., de Mendonça, A., Wallin, Å.K., Grimmer, T., Van Laere, K., Landau, S.M., Sabri, O., Na, D.L., Oliveira, C.R., Rinne, J.O., Soetewey, F., Gomez-Tortosa, E., Rüther, E., van Waalwijk van Doorn, L.J., Fleisher, A.S., Kapaki, E., Buchem, M.A. van, Meyer, P.T., Hausner, L., Schröder, J., Berckel, B.N. van, Rabinovici, G.D., Frisoni, G.B., Ford, L., van Berckel, B.N., Rami, L., Gabryelewicz, T., Mendonca, A. de, et al., Fortea, J., Flier, W.M. van der, Wallin, A., Jansen, W.J., Visser, P.J., Knol, D.L., Maier, W., Cohen, A.D., Lee, D.Y., Wiltfang, J., Paraskevas, G.P., Mok, V., Arnold, S.E., Marcusson, J., Tsolaki, M., Barthel, H., Santana, I., Klimkowicz-Mrowiec, A., Molinuevo, J.L., Engelborghs, S., Resende de Oliveira, C., Nordlund, A., Perera, G., de Leon, M., Kandimalla, R., Popp, J., Jagust, W.J., Seo, S.W., Van der Mussele, S.   +141 more
core   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

BMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li, Yi Wei, Ben Hu, Yafang Song, Xiaojia Chen, Nik Ahmad Nizam Nik Malek, Tongkai Chen   +6 more
wiley   +1 more source

Influence of C-terminal truncation of murine Serum amyloid A on fibril structure

Scientific Reports, 2017
Amyloid A (AA) amyloidosis is a systemic protein misfolding disease affecting humans and other vertebrates. While the protein precursor in humans and mice is the acute-phase reactant serum amyloid A (SAA) 1.1, the deposited fibrils consist mainly of C ...
Matthies Rennegarbe, Inga Lenter, Angelika Schierhorn, Romy Sawilla, Christian Haupt   +4 more
doaj   +1 more source

Purification of the Bacterial Amyloid "Curli" from Salmonella enterica Serovar Typhimurium and Detection of Curli from Infected Host Tissues. [PDF]

Bio Protoc, 2022
Sivaranjani M, Hansen EG, Perera SR, Flores PA, Tükel Ç, White AP.   +5 more
europepmc   +1 more source