Results 201 to 210 of about 92,288 (249)

Origin of class B J-domain proteins involved in amyloid transactions. [PDF]

open access: yesProc Natl Acad Sci U S A
Domanski P   +13 more
europepmc   +1 more source

Move beyond free radical theory of aging

open access: yesiMetaOmics, Volume 3, Issue 1, March 2026.
Free radicals play a dual, dose‐dependent role in aging. Low levels activate the key sensor adenosine 5'‐monophosphate‐activated protein kinase (AMPK), promoting cell survival mechanisms like autophagy and enhancing mitochondrial health. High levels, however, push AMPK to initiate cell death pathways, such as apoptosis. This positions AMPK as a central
Xiaofeng Dai, Meilan Hu, Ruohan Lyu
wiley   +1 more source

Chondroitin Sulfate Proteoglycans in CNS Development and Pathophysiology

open access: yesJournal of Neuroscience Research, Volume 104, Issue 3, March 2026.
Chondroitin sulfate proteoglycans (CSPGs) are critical components of the extracellular matrix in the central nervous system (CNS). In the developing CNS, CSPGs regulate neural precursor cells, neuronal migration, axon guidance, synapse organization, and peri‐neuronal net assembly.
Seyed Mojtaba Hosseini   +1 more
wiley   +1 more source

Recent Advancements in the Characterization of D‐Amino Acid and Isoaspartate Post‐Translational Modifications

open access: yesMass Spectrometry Reviews, Volume 45, Issue 2, Page 218-230, March/April 2026.
ABSTRACT One of the great triumphs of mass spectrometry‐based peptide and protein characterization is the characterization of their modifications as most modifications have a characteristic mass shift. What happens when the modification does not change the mass of the peptide?
Samuel Okyem, Jonathan V. Sweedler
wiley   +1 more source

Oral Dysbiosis and Neuroinflammation: Implications for Alzheimer's, Parkinson's and Mood Disorders. [PDF]

open access: yesMicroorganisms
Zavala-Medina LC   +8 more
europepmc   +1 more source

Bidirectional relationship between the biofilm of <i>Porphyromonas gingivalis</i> and the amyloid-beta peptide. [PDF]

open access: yesMicrobiol Spectr
Dumoulin D   +7 more
europepmc   +1 more source

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