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Microbial links to Alzheimer's disease. [PDF]
PLoS PathogCornitius CP, Perez EK, Lee SC.
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Expanding the amyloid landscape: structural plasticity of antimicrobial peptides
Landau M +7 more
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Bacterial Amyloids: Biogenesis and Biomaterials
2019Functional amyloid (FuBA) is produced by a large fraction of all bacterial species and represents a constructive use of the stable amyloid fold, in contrast to the pathological amyloid seen in neurodegenerative diseases. When assembled into amyloid, FuBA is unusually robust and withstands most chemicals including denaturants and SDS.
Line Friis Bakmann Christensen +4 more
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Characterization of Bacterial Amyloids by Nano-infrared Spectroscopy
2022Atomic force microscopy has been used for decades to study the topography of proteins during aggregation but with a lack of information on the secondary structure. On the contrary, infrared spectroscopy was able to study structural changes during the aggregation, but this analysis is complicated due to the presence of different species in mixtures and ...
Raussens, Vincent, Waeytens, Jehan
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Amyloid-like Properties of Bacterial Inclusion Bodies
Journal of Molecular Biology, 2005Bacterial inclusion bodies are major bottlenecks in protein production, narrowing the spectrum of relevant polypeptides obtained by recombinant DNA. While regarded as amorphous deposits formed by passive and rather unspecific precipitation of unfolded chains, we prove here that they are instead organized aggregates sharing important structural and ...
Mar, Carrió +4 more
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Functional Bacterial Amyloids in Biofilms
2011Functional bacterial amyloids constitute a group of important proteinaceous surface structures. Most amyloids are highly insoluble in water and resistant to most enzymes and thermal and chemical denaturants. Their functions in bacteria are still not well described but seem to include fimbriae and other cell appendages for adhesion and biofilm formation,
Nielsen, Per Halkjær +4 more
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Molecular architecture of bacterial amyloids in Bacillus biofilms
The FASEB Journal, 2019The formation of biofilms provides structural and adaptive bacterial response to the environment. In Bacillus species, the biofilm extracellular matrix is composed of exopolysaccharides, hydrophobins, and several functional amyloid proteins.
Mammeri, Nadia El +16 more
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