Physical Linkage of Naturally Complexed Bacterial Outer Membrane Proteins Enhances Immunogenicity [PDF]
ABSTRACTThe outer membrane proteins (OMPs) of bacterial pathogens are essential for their growth and survival and especially for attachment and invasion of host cells. Since the outer membrane is the interface between the bacterium and the host cell, outer membranes and individual OMPs are targeted for development of vaccines against many bacterial ...
H. Macmillan +4 more
semanticscholar +4 more sources
The Ton complex is a molecular motor at the inner membrane of Gram-negative bacteria that uses a proton gradient to apply forces on outer membrane (OM) proteins to permit active transport of nutrients into the periplasmic space.
Anna C. Ratliff +2 more
doaj +1 more source
Outer Membrane Vesicles Released From Aeromonas Strains Are Involved in the Biofilm Formation
Aeromonas spp. are Gram-negative rod-shaped bacteria ubiquitously distributed in diverse water sources. Several Aeromonas spp. are known as human and fish pathogens.
Soshi Seike +5 more
doaj +1 more source
Antimicrobial peptides (AMPs) are a unique and diverse group of molecules endowed with a broad spectrum of antibiotics properties that are being considered as new alternative therapeutic agents.
Angela Di Somma +13 more
doaj +1 more source
TonB-Dependent Transport Across the Bacterial Outer Membrane.
TonB-dependent transporters (TBDTs) are present in all gram-negative bacteria and mediate energy-dependent uptake of molecules that are too scarce or large to be taken up efficiently by outer membrane (OM) diffusion channels. This process requires energy
Augustinas Silale, B. van den Berg
semanticscholar +1 more source
The role and mechanisms of gram-negative bacterial outer membrane vesicles in inflammatory diseases
Outer membrane vesicles (OMVs) are spherical, bilayered, and nanosized membrane vesicles that are secreted from gram-negative bacteria. OMVs play a pivotal role in delivering lipopolysaccharide, proteins and other virulence factors to target cells ...
Shuoling Chen +3 more
semanticscholar +1 more source
Mechanisms of Protein Export across the Bacterial Outer Membrane [PDF]
Gram-negative bacteria secrete a wide range of proteins whose functions include biogenesis of organelles, such as pili and flagella; nutrient acquisition; virulence; and efflux of drugs and other toxins. Export of these proteins to the bacterial surface involves transport across the inner membrane (IM), periplasm, and outer membrane (OM) of the cell ...
Maria, Kostakioti +3 more
openaire +2 more sources
HELICOBACTER PYLORI OIPA VIRULENCE GENE AS A MOLECULAR MARKER OF SEVERE GASTROPATHIES [PDF]
Background: Helicobacter pylori is an etiologic agent of gastroduodenal diseases. The microorganism, considered a type I carcinogen, affects about 50% of the global population. H.
Diogo Nery MACIEL +4 more
doaj +1 more source
Subdominant antigens in bacterial vaccines: AM779 is subdominant in the Anaplasma marginale outer membrane vaccine but does not associate with protective immunity. [PDF]
Identification of specific antigens responsible for the ability of complex immunogens to induce protection is a major goal in development of bacterial vaccines.
Saleh M Albarrak +8 more
doaj +1 more source
Solute channels of the outer membrane: from bacteria to chloroplasts [PDF]
Chloroplasts, unique organelles of plants, originated from endosymbiosis of an ancestor of today's cyanobacteria with a mitochondria-containing host cell. It is assumed that the outer envelope membrane, which delimits the chloroplast from the surrounding
Aljamal J.A. +8 more
core +1 more source

