Bacterial Adaptor Membrane Fusion Proteins and the Structurally Dissimilar Outer Membrane Auxiliary Proteins Have Exchanged Central Domains in α-Proteobacteria [PDF]
International Journal of Microbiology, 2010 Transport systems frequently include auxiliary proteins that perform subfunctions within the transporter protein complex. Two such proteins found in Gram-negative bacteria are the Membrane Fusion Proteins (MFPs) and the Outer Membrane Auxiliary (OMA ...
Anthony Y. Xiao +2 more
doaj +2 more sources
Protein oligomerization in the bacterial outer membrane (Review) [PDF]
Molecular Membrane Biology, 2009 The formation of homo-oligomeric assemblies is a well-established characteristic of many soluble proteins and enzymes. Oligomerization has been shown to increase protein stability, allow allosteric cooperativity, shape reaction compartments and provide multivalent interaction sites in soluble proteins. In comparison, our understanding of the prevalence
Guoyu Meng +4 more
openalex +4 more sources
Living on the edge: Simulations of bacterial outer-membrane proteins.
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2016 Gram-negative bacteria are distinguished in part by a second, outer membrane surrounding them. This membrane is distinct from others, possessing an outer leaflet composed not of typical phospholipids but rather large, highly charged molecules known as lipopolysaccharides.
A. Pavlova +4 more
semanticscholar +4 more sources
The translocation assembly module (TAM) catalyzes the assembly of bacterial outer membrane proteins in vitro. [PDF]
Nat CommunWang X, Nyenhuis SB, Bernstein HD.
europepmc +3 more sources
The Assembly of Beta-Barrel Proteins into Bacterial Outer Membranes [PDF]
Biophysical Journal, 2017 In order to cause disease, bacterial pathogens must (i) avoid immune detection, (ii) inhibit immune responses, and (iii) induce pathology favoring bacterial replication. In gram-negative bacteria, pathogenesis depend on structures assembled in the bacterial outer membrane.
Trevor Lithgow
openalex +3 more sources
Bacterial Outer Membranes and Interactions with Membrane Proteins [PDF]
Biophysical Journal, 2015 Because the bacteria's outer membrane (OM) acts as an effective barrier against the permeation of both hydrophobic and hydrophilic compounds, gram-negative cell permeation is one of the biggest challenges to the discovery of novel antibiotics for bacterial infections and antibiotic resistance worldwide.
W. Im
semanticscholar +3 more sources
Selectivity in Lipid Binding to the Bacterial Outer Membrane Protein OmpF [PDF]
Biophysical Journal, 2000 The outer membrane porin OmpF from Escherichia coli has been reconstituted into lipid bilayers of defined composition, and fluorescence spectroscopy is used to characterize its interaction with the surrounding lipid. OmpF is a trimer within the membrane.
Aisling H. O’Keeffe +2 more
openalex +6 more sources
Frontiers in Microbiology, 2022 The Ton complex is a molecular motor at the inner membrane of Gram-negative bacteria that uses a proton gradient to apply forces on outer membrane (OM) proteins to permit active transport of nutrients into the periplasmic space.
Anna C. Ratliff +2 more
doaj +1 more source
Display of Recombinant Proteins on Bacterial Outer Membrane Vesicles by Using Protein Ligation [PDF]
Applied and Environmental Microbiology, 2018 ABSTRACT The Escherichia coli virulence factor hemoglobin protease (Hbp) has been engineered into a surface display system that can be expressed to high density on live E. coli and Salmonella enterica serovar Typhimurium cells or derived outer membrane ...
H. B. van den Berg van Saparoea +4 more
semanticscholar +6 more sources
Outer Membrane Vesicles Released From Aeromonas Strains Are Involved in the Biofilm Formation
Frontiers in Microbiology, 2021 Aeromonas spp. are Gram-negative rod-shaped bacteria ubiquitously distributed in diverse water sources. Several Aeromonas spp. are known as human and fish pathogens.
Soshi Seike +5 more
doaj +1 more source