Results 31 to 40 of about 1,657,824 (211)
Baseplate Component TssK and Spatio-Temporal Assembly of T6SS in Pseudomonas aeruginosa
Frontiers in Microbiology, 2019 The Gram-negative bacteria use the contractile multi-molecular structure, called the Type VI Secretion System (T6SS) to inject toxic products into eukaryotic and prokaryotic cells.
David Liebl +5 more
doaj +1 more source
Importance of protein Ser/Thr/Tyr phosphorylation for bacterial pathogenesis [PDF]
, 2020 Protein phosphorylation regulates a large variety of biological processes in all living cells. In pathogenic bacteria, the study of serine, threonine, and tyrosine (Ser/Thr/Tyr) phosphorylation has shed light on the course of infectious diseases, from ...
Bonne Kohler, Julie +18 more
core +1 more source
Staphylococcus aureus and Pseudomonas aeruginosa infectious keratitis: key bacterial mechanisms that mediate pathogenesis and emerging therapeutics [PDF]
, 2023 Bacterial keratitis (bacterial infection of the cornea) is a major cause of vision loss worldwide. Given the rapid and aggressive nature of the disease, immediate broad-spectrum antibiotics are essential to adequately treat this disease.
Rachel A. F. Wozniak, Shalini Shah
core +1 more source
Acetylation of Lysine 243 Inhibits the oriC Binding Ability of DnaA in Escherichia coli
Frontiers in Microbiology, 2017 DNA replication initiation is a central event in the cell cycle, and it is strictly controlled by multiple regulatory mechanisms. Our previous work showed that acetylation of residue lysine (K) 178 prevents DnaA from binding to ATP, which leads to the ...
Yu-Feng Yao +4 more
doaj +1 more source
New roles for glutathione: Modulators of bacterial virulence and pathogenesis
, 2021 Low molecular weight (LMW) thiols contain reducing sulfhydryl groups that are important for maintaining antioxidant defense in the cell. Aside from the traditional roles of LMW thiols as redox regulators in bacteria, glutathione (GSH) has been reported ...
Joanne Wei Kay Ku, Yunn-Hwen Gan
core +1 more source
F1000Research, 2013 Background: Bacterial pathogens can manipulate or subvert host tissue cells to their advantage at different stages during infection, from initial colonization in primary host niches to dissemination. Recently, we have shown that Mycobacterium leprae (ML),
Toshihiro Masaki +4 more
doaj +1 more source
The bacterial pathogenesis and treatment of pouchitis [PDF]
Therapeutic Advances in Gastroenterology, 2010 Restorative proctocolectomy (RPC) with ileal pouch-anal anastomosis is the operation of choice for patients with ulcerative colitis. Pouchitis is the most common cause of pouch dysfunction. Although the pathogenesis of this disease is not well understood, bacteria have been implicated in the disease process.
S.D. McLaughlin +4 more
openaire +3 more sources
Large-scale identification of pathogenicity factors in "Bartonella" by signature-tagged mutagenesis [PDF]
, 2005 Bartonellae are bacterial pathogens uniquely adapted to cause intraerythrocytic infection in their mammalian reservoir hosts. In the case of human-specific Bartonella bacilliformis and Bartonella quintana, the intraerythrocytic bacteremia leads to the ...
Saenz Dürrmeier, Luis-Henri
core +1 more source
F1000Research, 2013 Background: Bacterial pathogens can manipulate or subvert host tissue cells to their advantage at different stages during infection, from initial colonization in primary host niches to dissemination. Recently, we have shown that Mycobacterium leprae (ML),
Toshihiro Masaki +4 more
doaj +1 more source
The Role of Lymphostatin/EHEC Factor for Adherence-1 in the Pathogenesis of Gram Negative Infection
, 2010 Lymphostatin/EHEC factor for adherence-1 is a novel large toxin represented in various Gram negative bacteria, highly associated with the development of infectious diarrhea and hemolytic uremic syndrome.
Klapproth
core +2 more sources