Results 101 to 110 of about 131,877 (321)

Over two decades of research on the marine RNA virosphere

iMeta, Volume 1, Issue 4, December 2022., 2022
Advances in meta‐omics provide a surge of marine RNA virus information. Deep marine virus discovery contributes greatly to the megataxonomy of RNA viruses. Understanding diversity and biogeography helps reveal the significance of marine RNA viruses, including evolutionary trajectories, hierarchical taxonomy, and ecological importance.
Meng‐en Liao, Yunyi Xie, Mang Shi, Jie Cui   +3 more
wiley   +1 more source

Structure and Antigenicity of Kaposi's Sarcoma‐Associated Herpesvirus Glycoprotein B

Advanced Science, EarlyView.
Kaposi's sarcoma‐associated herpesvirus (KSHV) causes severe cancers without effective treatments. This study presents an atomic model of KSHV's critical infection protein, gB, revealing a unique structure shared with related herpesviruses like Epstein‐Barr virus (EBV). The structural similarity highlights vulnerable targets for antibodies, guiding the
Xin‐Yan Fang, Cong Sun, Chu Xie, Bing‐Zhen Cheng, Zheng‐Zhou Lu, Ge‐Xin Zhao, Sen‐Fang Sui, Mu‐Sheng Zeng, Zheng Liu   +8 more
wiley   +1 more source

Isolation of GAL Tularemia Bacteriophage and its Characteristics

Проблемы особо опасных инфекций, 2008
Temperate tularemia bacteriophage was for the first time isolated from the organs of guinea-pig infected with live tularemia vaccine strain N 15 of RIEH line.
A. A. Grigor’ev, I. V. Borisevich, I. V. Darmov, V. P. Bondarev, S. L. Kuznetsov, A. V. Mironin, I. P. Pogorelsky, A. V. Letarov, E. E. Koulikov, A. A. Manykin   +9 more
doaj   +1 more source

Recent advances in bacteriophage-based therapeutics: Insight into the post-antibiotic era

Acta Pharmaceutica Sinica B, 2022
Antibiotic resistance is one of the biggest threats to global health, as it can make the treatment of bacterial infections in humans difficult owing to their high incidence rate, mortality, and treatment costs.
Hao Ling, Xinyu Lou, Qiuhua Luo, Zhonggui He, Mengchi Sun, Jin Sun   +5 more
doaj  

The effect of genome length on ejection forces in bacteriophage lambda [PDF]

arXiv, 2005
A variety of viruses tightly pack their genetic material into protein capsids that are barely large enough to enclose the genome. In particular, in bacteriophages, forces as high as 60 pN are encountered during packaging and ejection, produced by DNA bending elasticity and self-interactions. The high forces are believed to be important for the ejection
arxiv  

High‐fidelity in vitro packaging of diverse synthetic cargo into encapsulin protein cages

Angewandte Chemie International Edition, Accepted Article.
Cargo‐filled protein cages are powerful tools in biotechnology with demonstrated potential as catalytic nanoreactors and vehicles for targeted drug delivery. While endogenous biomolecules can be packaged into protein cages during their expression and self‐assembly inside cells, synthetic cargo molecules are typically incompatible with live cells and ...
Taylor Szyszka, Rezwan Siddiquee, Alex Loustau, Lachlan S. R. Adamson, Claire Rennie, Tiancheng Huang, Reginald Young, Andrew Care, Yu Heng Lau   +8 more
wiley   +1 more source

Functional Ambidexterity of an Ancient Nucleic Acid‐Binding Domain

Angewandte Chemie International Edition, Accepted Article.
The helix‐hairpin‐helix (HhH) motif is an ancient and ubiquitous nucleic acid‐binding element that has emerged as a model system for studying the evolution of dsDNA‐binding domains from simple peptides that phase separate with RNA. We analyzed the entire putative evolutionary trajectory of the HhH motif – from a flexible peptide to a folded domain ...
Liam Longo, Orit Weil-Ktorza, Segev Naveh-Tassa, Yael Fridmann-Sirkis, Dragana Despotović, Kesava Phaneendra Cherukuri, Tatsuya Corlett, Yaakov Levy, Norman Metanis   +8 more
wiley   +1 more source

Stability study in selected conditions and biofilm-reducing activity of phages active against drug-resistant Acinetobacter baumannii

Scientific Reports
Acinetobacter baumannii is currently a serious threat to human health, especially to people with immunodeficiency as well as patients with prolonged hospital stays and those undergoing invasive medical procedures.
Natalia Bagińska, Ilona Grygiel, Filip Orwat, Marek Adam Harhala, Adam Jędrusiak, Elżbieta Gębarowska, Sławomir Letkiewicz, Andrzej Górski, Ewa Jończyk-Matysiak   +8 more
doaj   +1 more source

THE MULTIPLICATION OF BACTERIOPHAGE IN VIVO AND ITS PROTECTIVE EFFECT AGAINST AN EXPERIMENTAL INFECTION WITH SHIGELLA DYSENTERIAE [PDF]

, 1943
René Dubos, June Hookey Straus, Cynthia Pierce   +2 more
openalex   +1 more source

Genomic Insights Into a Strong Biofilm‐Forming Enterococcus faecalis MTR_EFS01 Strain Isolated From a Shrimp in Bangladesh

Animal Research and One Health, EarlyView.
This study characterizes a multidrug‐resistant and strong biofilm‐forming Enterococcus faecalis strain obtained from a shrimp sample in Bangladesh. ABSTRACT Enterococcus faecalis is known for its ability to form strong biofilms and its role as an opportunistic pathogen. In this study, we screened and characterized a multidrug‐resistant (MDR) and strong
Md. Ashek Ullah, Md. Saiful Islam, Md. Liton Rana, Jayedul Hassan, Md. Tanvir Rahman   +4 more
wiley   +1 more source