Results 101 to 110 of about 261,858 (336)
Process of infection with bacteriophage phi X 174 XXXVIII. Replication of phi chi 174 replicative form in vivo [PDF]
The replication of bacteriophage phi X 174 replicative-form DNA has been studied by structural analysis of pulse-labeled replicative-intermediate molecules.
Fukuda, Akio, Sinsheimer, Robert L.
core
Supported lipid bilayers coupled with multielectrode array devices offer significant promise for pathogen–host cell membrane interaction studies. This work demonstrates, for the first time, the compatibility of this platform with biological fluids, in this case whole human blood, essential for any future point‐of‐care applications; as well as its ...
Alexandra Wheeler+4 more
wiley +1 more source
Antibiotics targeting bacterial protein synthesis reduce the lytic activity of bacteriophages
Combination therapy of bacteriophages and antibiotics requires careful selection of specific antibiotics as it is crucial towards determining the success of phage therapy to treat multiple drug-resistant bacterial infections.
Medhavi Vashisth+5 more
doaj
Although phage discovery is an unquestionable merit of the English bacteriologist Frederick W. Twort and the Canadian–French microbiologist Félix d’Hérelle, who both discovered phages over 100 years ago, the Polish history of phage studies also dates ...
Maciej Żaczek+8 more
doaj +1 more source
Osmotic pressure: resisting or promoting DNA ejection from phage [PDF]
Recent in vitro experiments have shown that DNA ejection from bacteriophage can be partially stopped by surrounding osmotic pressure when ejected DNA is digested by DNase I on the course of ejection.
Castelnovo, Martin+4 more
core +3 more sources
A novel approach enables facile and reproducible fabrication of gold nanoparticle arrays with tunable near‐infrared plasmonic properties and enhanced sensing accuracy. Using advanced lithography and ion milling, combined with innovative surface chemistry, the approach minimizes ohmic losses and non‐specific sorption, improving biomolecular detection ...
Dario Cattozzo Mor+12 more
wiley +1 more source
Digital Bioassays on the Slipchip Microfluidic Devices
This review summarizes recent advances in SlipChip‐based digital bioassays, highlighting their simple “load and slip” operation for fluid partitioning which eliminate the need for sophisticated fluidic systems. Applications include digital nucleic acid analysis, digital protein analysis and single‐cell analysis, demonstrating the platform‘s potential ...
Qingqing Luo+5 more
wiley +1 more source
Direction of Translation and Size of Bacteriophage [var phi]X174 Cistrons [PDF]
Translation of the bacteriophage [var phi]X174 genome follows cistron order D-E-F-G-H-A-B-C. To establish this, the position of a nonsense mutation on the genetic map was compared with the physical size (molecular weight) of the appropriate protein ...
Benbow, Robert M.+3 more
core
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu+7 more
wiley +1 more source
Isolation of GAL Tularemia Bacteriophage and its Characteristics
Temperate tularemia bacteriophage was for the first time isolated from the organs of guinea-pig infected with live tularemia vaccine strain N 15 of RIEH line.
A. A. Grigor’ev+9 more
doaj +1 more source