Results 51 to 60 of about 434,771 (384)

Phages in Therapy and Prophylaxis of American Foulbrood – Recent Implications From Practical Applications

Frontiers in Microbiology, 2020
American foulbrood is one of the most serious and yet unsolved problems of beekeeping around the world, because it causes a disease leading to the weakening of the vitality of honey bee populations and huge economic losses both in agriculture and ...
Ewa Jończyk-Matysiak, Ewa Popiela, Barbara Owczarek, Katarzyna Hodyra-Stefaniak, Kinga Świtała-Jeleń, Norbert Łodej, Dominika Kula, Joanna Neuberg, Paweł Migdał, Natalia Bagińska, Filip Orwat, Beata Weber-Dąbrowska, Beata Weber-Dąbrowska, Adam Roman, Andrzej Górski, Andrzej Górski   +15 more
doaj   +1 more source

Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease

Nature, 2019
Chronic liver disease due to alcohol-use disorder contributes markedly to the global burden of disease and mortality1–3. Alcoholic hepatitis is a severe and life-threatening form of alcohol-associated liver disease.
Yi Duan, C. Llorente, S. Lang, K. Brandl, H. Chu, Lu Jiang, Richard C. White, Thomas H. Clarke, K. Nguyen, M. Torralba, Yan Shao, Jinyuan Liu, A. Hernandez-Morales, L. Lessor, Imran R. Rahman, Y. Miyamoto, Melissa Ly, Bei Gao, Weizhong Sun, Roman Kiesel, Felix Hutmacher, Suhan Lee, M. Ventura-Cots, F. Bosques-Padilla, E. Verna, J. Abraldes, Robert S. Brown, Victor Vargas, J. Altamirano, J. Caballería, D. Shawcross, S. Ho, A. Louvet, M. Lucey, P. Mathurin, G. Garcia‐Tsao, R. Bataller, Xin M. Tu, L. Eckmann, W. A. van der Donk, R. Young, T. Lawley, P. Stärkel, D. Pride, D. Fouts, B. Schnabl   +45 more
semanticscholar   +1 more source

Application of bacteriophages [PDF]

Microbiology Australia, 2017
The emergence of antibiotic-resistant bacteria and decrease in the discovery rate of novel antibiotics takes mankind back to the ‘pre-antibiotic era' and search for alternative treatments. Bacteriophages have been one of promising alternative agents which can be utilised for medicinal and biological control purposes in agriculture and related fields ...
Aminov, Rustam, Caplin, Jonathan, Chanishvili, Nina, Coffey, Aidan, Cooper, Ian, De Vos, Daniel, Doskar, Jiri, Friman, Ville-Petri, Kurtboke, Ipek, Pantucek, Roman, Pirnay, Jean-Paul, Resch, Gregory, Rohde, Christine, Sybesma, Wilbert, Wittmann, Johannes   +14 more
openaire   +4 more sources

Phage-Phagocyte Interactions and Their Implications for Phage Application as Therapeutics

Viruses, 2017
Phagocytes are the main component of innate immunity. They remove pathogens and particles from organisms using their bactericidal tools in the form of both reactive oxygen species and degrading enzymes—contained in granules—that are potentially toxic ...
Ewa Jończyk-Matysiak, Beata Weber-Dąbrowska, Barbara Owczarek, Ryszard Międzybrodzki, Marzanna Łusiak-Szelachowska, Norbert Łodej, Andrzej Górski   +6 more
doaj   +1 more source

Direct comparison of nick-joining activity of the nucleic acid ligases from bacteriophage T4 [PDF]

, 2006
The genome of bacteriophage T4 encodes three polynucleotide ligases, which seal the backbone of nucleic acids during infection of host bacteria. The T4Dnl (T4 DNA ligase) and two RNA ligases [T4Rnl1 (T4 RNA ligase 1) and T4Rnl2] join a diverse array of ...
Amitsur, Arabshahi, Bebenek, Begley, Bellacosa, Blondal, Blondal, Cherepanov, Cherepanov, Clepet, Della, Desmond R. Bullard, Doherty, Engler, Fareed, Higgins, Ho, Ho, Kaufmann, Keppetipola, Kornberg, Kuhn, Lavesa-Curto, Lehman, Markham, Martins, Martins, Miller, Moore, Nandakumar, Nandakumar, Nandakumar, Nick McElhinny, Omari, Pascal, Pitcher, Pitcher, Richard P. Bowater, Rossi, Ruiz, Runnels, Rydberg, Sambrook, Sekiguchi, Shuman, Shuman, Snopek, Sriskanda, Stuart, Timson, Tomkinson, Wang, Wang, Weiss, Wilkinson, Wilkinson, Wilkinson, Wood, Wood, Worthey, Yin, Yin   +61 more
core   +4 more sources

Antibiotics targeting bacterial protein synthesis reduce the lytic activity of bacteriophages

Virus Research, 2022
Combination therapy of bacteriophages and antibiotics requires careful selection of specific antibiotics as it is crucial towards determining the success of phage therapy to treat multiple drug-resistant bacterial infections.
Medhavi Vashisth, Shikha Yashveer, Taruna Anand, Nitin Virmani, Bidhan Chand Bera, Rajesh Kumar Vaid   +5 more
doaj   +1 more source

Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multicentre, multinational, retrospective observational study

Nature Microbiology
In contrast to the many reports of successful real-world cases of personalized bacteriophage therapy (BT), randomized controlled trials of non-personalized bacteriophage products have not produced the expected results.
J. Pirnay, S. Djebara, Griet Steurs, Johann Griselain, C. Cochez, Steven De Soir, T. Glonti, An Spiessens, Emily Vanden Berghe, Sabrina Green, J. Wagemans, C. Lood, Eddie Schrevens, N. Chanishvili, M. Kutateladze, Mathieu de Jode, P. Ceyssens, J. Draye, G. Verbeken, D. De Vos, T. Rose, J. Onsea, Brieuc Van Nieuwenhuyse, P. Soentjens, R. Lavigne, M. Merabishvili   +25 more
semanticscholar   +1 more source

Bacteriophage therapy against Pseudomonas aeruginosa biofilms: a review

Annals of Clinical Microbiology and Antimicrobials, 2020
Multi-Drug Resistant (MDR) Pseudomonas aeruginosa is one of the most important bacterial pathogens that causes infection with a high mortality rate due to resistance to different antibiotics.
Z. Chegini, Amin Khoshbayan, Majid Taati Moghadam, Iman Farahani, Parham Jazireian, A. Shariati   +5 more
semanticscholar   +1 more source

Innovating on Well Biofouling Remediation: A Bacteriophage Cocktail Approach [PDF]

, 2014
Waller Creek Working ...
Bae, Sungwoo, Kirisits, Mary Jo, Maestre, Juan Pedro, Ochoa, Gustavo   +3 more
core   +1 more source

Recent advances in bacteriophage-based therapeutics: Insight into the post-antibiotic era

Acta Pharmaceutica Sinica B, 2022
Antibiotic resistance is one of the biggest threats to global health, as it can make the treatment of bacterial infections in humans difficult owing to their high incidence rate, mortality, and treatment costs.
Hao Ling, Xinyu Lou, Qiuhua Luo, Zhonggui He, Mengchi Sun, Jin Sun   +5 more
doaj   +1 more source