Results 51 to 60 of about 249,047 (357)

Temperate Bacteriophages—The Powerful Indirect Modulators of Eukaryotic Cells and Immune Functions

Viruses, 2021
Bacteriophages are natural biological entities that limit the growth and amplification of bacteria. They are important stimulators of evolutionary variability in bacteria, and currently are considered a weapon against antibiotic resistance of bacteria ...
Martyna Cieślik, Natalia Bagińska, Ewa Jończyk-Matysiak, Alicja Węgrzyn, Grzegorz Węgrzyn, Andrzej Górski   +5 more
doaj   +1 more source

Direct comparison of nick-joining activity of the nucleic acid ligases from bacteriophage T4 [PDF]

, 2006
The genome of bacteriophage T4 encodes three polynucleotide ligases, which seal the backbone of nucleic acids during infection of host bacteria. The T4Dnl (T4 DNA ligase) and two RNA ligases [T4Rnl1 (T4 RNA ligase 1) and T4Rnl2] join a diverse array of ...
Amitsur, Arabshahi, Bebenek, Begley, Bellacosa, Blondal, Blondal, Cherepanov, Cherepanov, Clepet, Della, Desmond R. Bullard, Doherty, Engler, Fareed, Higgins, Ho, Ho, Kaufmann, Keppetipola, Kornberg, Kuhn, Lavesa-Curto, Lehman, Markham, Martins, Martins, Miller, Moore, Nandakumar, Nandakumar, Nandakumar, Nick McElhinny, Omari, Pascal, Pitcher, Pitcher, Richard P. Bowater, Rossi, Ruiz, Runnels, Rydberg, Sambrook, Sekiguchi, Shuman, Shuman, Snopek, Sriskanda, Stuart, Timson, Tomkinson, Wang, Wang, Weiss, Wilkinson, Wilkinson, Wilkinson, Wood, Wood, Worthey, Yin, Yin   +61 more
core   +4 more sources

Spreading dynamics of an infection in a growing population [PDF]

arXiv, 2021
Bacteriophages spreading through populations of bacteria offer relatively simple, tuneable systems for testing mathematical models of range expansion. However, such models typically assume a static state into which to expand, which is not generally valid for bacterial-bacteriophage populations, where both the host (bacteria) and the infectious agent ...
arxiv  

Application of bacteriophages [PDF]

Microbiology Australia, 2017
The emergence of antibiotic-resistant bacteria and decrease in the discovery rate of novel antibiotics takes mankind back to the ‘pre-antibiotic era' and search for alternative treatments. Bacteriophages have been one of promising alternative agents which can be utilised for medicinal and biological control purposes in agriculture and related fields ...
Aminov, Rustam, Caplin, Jonathan, Chanishvili, Nina, Coffey, Aidan, Cooper, Ian, De Vos, Daniel, Doskar, Jiri, Friman, Ville-Petri, Kurtboke, Ipek, Pantucek, Roman, Pirnay, Jean-Paul, Resch, Gregory, Rohde, Christine, Sybesma, Wilbert, Wittmann, Johannes   +14 more
openaire   +4 more sources

Phage-Phagocyte Interactions and Their Implications for Phage Application as Therapeutics

Viruses, 2017
Phagocytes are the main component of innate immunity. They remove pathogens and particles from organisms using their bactericidal tools in the form of both reactive oxygen species and degrading enzymes—contained in granules—that are potentially toxic ...
Ewa Jończyk-Matysiak, Beata Weber-Dąbrowska, Barbara Owczarek, Ryszard Międzybrodzki, Marzanna Łusiak-Szelachowska, Norbert Łodej, Andrzej Górski   +6 more
doaj   +1 more source

Phage therapy: An alternative to antibiotics in the age of multi-drug resistance. [PDF]

, 2017
The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice.
Koskella, Britt, Lin, Derek, Lin, Henry
core   +1 more source

A Single-Molecule Hershey-Chase Experiment [PDF]

Current Biology (2012), Volume 22, Issue 14, 1339-1343, 2012
Ever since Hershey and Chase used phages to establish DNA as the carrier of genetic information in 1952, the precise mechanisms of phage DNA translocation have been a mystery. While bulk measurements have set a time scale for in vivo DNA translocation during bacteriophage infection, measurements of DNA ejection by single bacteriophages have only been ...
arxiv   +1 more source

Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process [PDF]

, 2017
Bacteriophages are bacterial viruses that infect the host after successful receptor recognition and adsorption to the cell surface. The irreversible adherence followed by genome material ejection into host cell cytoplasm must be preceded by the passage ...
Briers, Yves, Drulis-Kawa, Zuzanna, Maciejewska, Barbara, Majkowska-Skrobek, Grazyna, Łątka, Agnieszka   +4 more
core   +1 more source

Architecture of viral genome-delivery molecular machines. [PDF]

, 2014
From the abyss of the ocean to the human gut, bacterial viruses (or bacteriophages) have colonized all ecosystems of the planet earth and evolved in sync with their bacterial hosts. Over 95% of bacteriophages have a tail that varies greatly in length and
Bhardwaj, Anshul, Cingolani, Gino, Olia, Adam S.   +2 more
core   +3 more sources

Highly Sensitive Bacteriophage-Based Detection of Brucella abortus in Mixed Culture and Spiked Blood

Viruses, 2017
For decades, bacteriophages (phages) have been used for Brucella species identification in the diagnosis and epidemiology of brucellosis. Traditional Brucella phage typing is a multi-day procedure including the isolation of a pure culture, a step that ...
Kirill V. Sergueev, Andrey A. Filippov, Mikeljon P. Nikolich   +2 more
doaj   +1 more source