The Human Virome in Infectious Diseases: Insights from Chronic and Acute Infections Across Body Sites-A Narrative Review. [PDF]
Feletti R +4 more
europepmc +1 more source
Synergistic engineering of Casδ nuclease for robust genome editing
A hierarchical engineering strategy was used to enhance the editing activity of Casδ, yielding an optimized variant termed enCasδ. This variant enables robust genome editing in animal cells and plants, with overall editing performance comparable to that of SpCas9 and other Cas12 nucleases.
Fanghui Ge +16 more
wiley +1 more source
Erratum for Levesque et al., "Complete genome sequence of bacteriophages Merry and Sunny infecting <i>Microbacterium chocolatum</i> strain GAI20246-6 isolated from an outdoor commercial algal pond". [PDF]
Levesque AV +8 more
europepmc +1 more source
SIB1‐SEC23A undergo ER to chloroplast relocalization to mediate immunity in Arabidopsis thaliana
SEC23A mediates membrane trafficking between the endoplasmic reticulum (ER) and Golgi apparatus and interacts with the immunity protein SIGMA FACTOR‐BINDING PROTEIN1 in Arabidopsis. Under stress, both proteins relocate from the ER to chloroplasts, suppressing photosynthesis genes and enhancing defense genes.
Jialin Peng +7 more
wiley +1 more source
Complete genome sequence of a <i>Streptococcus equi</i> subsp. <i>equi</i> bacteriophage isolated from raw sewage water in Tokyo. [PDF]
Shirakawa K +13 more
europepmc +1 more source
20th Anniversary of human‐induced pluripotent stem cells and the role of microscopy
Abstract It has been 20 years since the pioneering work of Shinya Yamanaka and Kazutoshi Takahashi at Kyoto University led to the first successful generation of induced pluripotent stem cells (iPSCs) from mouse embryonic and adult fibroblast cells. iPSCs have the capacity to differentiate into any type of cell in the human body, and as such, they have ...
Philomena Hallford +3 more
wiley +1 more source
Species-level virome profiling reveals compositional differences in the gut prokaryotic DNA virome of people with HIV-1 on antiretroviral therapy. [PDF]
Zhang J +3 more
europepmc +1 more source
The Role of Viruses in the Pathogenesis of Periodontitis
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte +2 more
wiley +1 more source
From structure to therapy: two novel bacteriophages from swine wastewater with divergent genomes converge in combating <i>Escherichia coli</i> and <i>Salmonella</i> infections. [PDF]
Zhang L +11 more
europepmc +1 more source
CRISPR spacer profiling and prophage mining reveal diverse bacteriophages associated with <i>Streptococcus Mutans</i>. [PDF]
Chen X +8 more
europepmc +1 more source

