Results 1 to 10 of about 3,073 (104)

Bacterioruberin extract from Haloarchaea Haloferax marinum: Component identification, antioxidant activity and anti-atrophy effect in LPS-treated C2C12 myotubes. [PDF]

Microb Biotechnol
The composition of C50 carotenoid bacterioruberin and its derivatives were identified in halophilic archaea Haloferax marinum MBLA0078, which exhibit potent antioxidant properties and protect against lipopolysaccharide‐induced C2C12 myotube atrophy, possibly through Akt/mTOR pathway activation, indicating their potential as natural antioxidants and ...
Lee H, Cho ES, Hwang CY, Cao L, Kim MB, Lee SG, Seo MJ.   +6 more
europepmc   +5 more sources

Characterization and Functional Evaluation of Carotenoids From Haloarcula rubripromontorii BS2. [PDF]

Microbiologyopen
Fractionation and comprehensive characterization of C50 carotenoids from Haloarcula rubripromontorii BS2, identified all‐trans bacterioruberin as the predominant isomer. The haloarchaeal carotenoid exhibited strong antioxidant activity, photostability in oil and was biocompatible with human keratinocytes, highlighting their potential as sustainable ...
Nagar DN, Das D, Aduri R, Braganca JM.
europepmc   +2 more sources

Nebulized Bacterioruberin/Astaxanthin-Loaded Nanovesicles: Antitumoral Activity and Beyond. [PDF]

Int J Mol Sci
The membranes of halophilic archaea are a source of novel biomaterials, mainly of isoprenoid nature, with therapeutic properties practically unraveled. Here, we explored the antitumoral activity of neutral archaeolipids (NAs, such as bacterioruberin, astaxanthin, and dihydrosqualene) present in the total archaeolipids (TAs) (a fraction from the first ...
González Epelboim VRD, Lamas DG, Huck-Iriart C, Caputo EN, Altube MJ, Jerez HE, Simioni YR, Ghosal K, Morilla MJ, Higa LH, Romero EL.   +10 more
europepmc   +3 more sources

Recovery of bacterioruberin and proteins using aqueous solutions of surface-active compounds. [PDF]

RSC Adv, 2022
Bacterioruberin and proteins were recovered from a marine bacterium by using aqueous solutions of surface-active compounds.
Vaz BMC, Kholany M, Pinto DCGA, Macário IPE, Veloso T, Caetano T, Pereira JL, Coutinho JAP, Ventura SPM.   +8 more
europepmc   +4 more sources

Microbial Bacterioruberin: A Comprehensive Review. [PDF]

Indian J Microbiol
Bacterioruberin (BR) is a fat-soluble, dipolar, reddish pigment predominantly found in halophilic archaea. BR is a rare C50 carotenoid from the xanthophyll family, and it has been extensively studied for its potent antioxidant properties, such as its ability to protect cells from oxidative stress.
Palanisamy M, Ramalingam S.
europepmc   +3 more sources

Effects of Bacterioruberin-Rich Haloarchaeal Carotenoid Extract on the Thermal and Oxidative Stabilities of Fish Oil. [PDF]

Molecules, 2023
This study aimed to assess the efficacy of a bacterioruberin-rich carotenoid extract (HAE) derived from the halophilic archaea Halorubrum ezzemoulense DSM 19316 in protecting crude fish oil against thermal oxidation. The research used fish oil derived from anchovies, which had a peroxide value (PV) of 6.44 ± 0.81 meq O2 kg−1.
Kesbiç FI, Metin H, Fazio F, Parrino V, Kesbiç OS.   +4 more
europepmc   +4 more sources

The biosynthesis mechanism of bacterioruberin in halophilic archaea revealed by genome and transcriptome analysis. [PDF]

Appl Environ Microbiol
ABSTRACT Halophilic archaea are promising microbial cell factories for bacterioruberin (BR) production. BR is a natural product with multi-bioactivities, allowing potential application in many fields. In the previous work, a haloarchaeon Halorubrum sp.
Ma Y, Sun Z, Yang H, Xie W, Song M, Zhang B, Sui L.   +6 more
europepmc   +3 more sources

Bacterioruberin: Biosynthesis, Antioxidant Activity, and Therapeutic Applications in Cancer and Immune Pathologies. [PDF]

Mar Drugs
Halophilic archaea, also termed haloarchaea, are a group of moderate and extreme halophilic microorganisms that constitute the major microbial populations in hypersaline environments. In these ecosystems, mainly aquatic, haloarchaea are constantly exposed to ionic and oxidative stress due to saturated salt concentrations and high incidences of UV ...
Giani M, Pire C, Martínez-Espinosa RM.
europepmc   +5 more sources

Optimization of bacterioruberin production from Halorubrum ruber and assessment of its antioxidant potential. [PDF]

Microb Cell Fact
AbstractHaloarchaea produce bacterioruberin, a major C50 carotenoid with antioxidant properties that allow for its potential application in the food, cosmetic, and pharmaceutical industries. This study aimed to optimize culture conditions for total carotenoid, predominantly comprising bacterioruberin, production using Halorubrum ruber MBLA0099.
Hwang CY, Cho ES, Kim S, Kim K, Seo MJ.
europepmc   +4 more sources

Optimized production of bacterioruberin from "Haloferax marinum" using one-factor-at-a-time and central composite design approaches. [PDF]

Bioresour Bioprocess
AbstractHaloarchaea represents a unique group of microorganisms that have adapted to thrive in high-salt environments. These microbes produce distinctive biomolecules, some of which exhibit extraordinary properties. One such biomolecule is bacterioruberin, a prominent red-pigmented C50 carotenoid commonly found in halophilic archaea, renowned for its ...
Cho ES, Hwang CY, Seo MJ.
europepmc   +4 more sources