Results 91 to 100 of about 1,246,132 (248)
Coordination of membrane and actin cytoskeleton dynamics during filopodia protrusion. [PDF]
PLoS ONE, 2009 Leading edge protrusion of migrating cells involves tightly coordinated changes in the plasma membrane and actin cytoskeleton. It remains unclear whether polymerizing actin filaments push and deform the membrane, or membrane deformation occurs ...
Changsong Yang +4 more
doaj +1 more source
A Hybrid Segmentation and D-bar Method for Electrical Impedance Tomography [PDF]
, 2015 The Regularized D-bar method for Electrical Impedance Tomography provides a rigorous mathematical approach for solving the full nonlinear inverse problem directly, i.e. without iterations.
Hamilton, Sarah +3 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Regulation of actin-Spectrin cytoskeleton by ICA69 at the Drosophila neuromuscular junction
Communicative & Integrative Biology, 2018 Bin-Amphiphysin-Rvs (BAR) domain containing proteins with their membrane deforming properties have emerged as key players in shaping up neuronal morphology and regulating cytoskeletal dynamics.
Bhagaban Mallik, Vimlesh Kumar
doaj +1 more source
GRAF1 forms a complex with MICAL-L1 and EHD1 to cooperate in tubular recycling endosome vesiculation
Frontiers in Cell and Developmental Biology, 2014 The biogenesis of tubular recycling endosomes (TREs) and their subsequent vesiculation after cargo-sorting has occurred, is essential for receptor and lipid recycling to the plasma membrane.
Bishuang eCai +3 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Frontiers in Immunology, 2020 Anti-drug antibody formation poses tremendous obstacles for optimal treatment of hemophilia A (HA). In this study, we sought to utilize chimeric receptor-modified natural regulatory T cells (Tregs) to target FVIII-specific memory B cells, which are ...
Alessandra De Paula Pohl +3 more
doaj +1 more source
SNX9: An Unconventional Bar Domain Protein? [PDF]
Biophysical Journal, 2021 Feng-Ching Tsai +3 more
openaire +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
PLoS ONE, 2012 Cell motility, adhesion and phagocytosis are controlled by actin and membrane remodelling processes. Bridging integrator-2 (Bin2) also called Breast cancer-associated protein 1 (BRAP1) is a predicted N-BAR domain containing protein with unknown function ...
María José Sánchez-Barrena +6 more
doaj +1 more source