Results 21 to 30 of about 1,383,161 (168)
Disease Models & Mechanisms, 2020 Skeletal muscle development and regeneration are tightly regulated processes. How the intracellular organization of muscle fibers is achieved during these steps is unclear. Here, we focus on the cellular and physiological roles of amphiphysin 2 (BIN1), a
Ivana Prokic +18 more
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Communicative & Integrative Biology, 2010 The F-BAR domain is emerging as an important player in membrane remodeling pathways. F-BAR domain proteins couple membrane remodeling with actin dynamics associated with endocytic pathways and filopodium formation. Here, we provide a comprehensive analysis of F-BAR domain proteins in terms of their evolutionary relationships and protein function. F-BAR
Sohail, Ahmed +4 more
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Cells, 2020 The budding yeast Saccharomyces cerevisiae has an actin cytoskeleton that comprises a set of protein components analogous to those found in the actin cytoskeletons of higher eukaryotes. Furthermore, the actin cytoskeletons of S.
Zain Akram +8 more
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iScience, 2020 Summary: Membrane curvature has emerged as an intriguing physical principle underlying biological signaling and membrane trafficking. The CIP4/FBP17/Toca-1 F-BAR subfamily is unique in the BAR family because its structurally folded F-BAR domain does not ...
Maohan Su +6 more
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Membrane Curvature: How BAR Domains Bend Bilayers [PDF]
Current Biology, 2004 An important new structure suggests the BAR domain is a membrane-binding module that can both produce and sense membrane curvature. BAR resembles a banana that binds membranes electrostatically through its positively charged, concave surface.
Zimmerberg, Joshua, McLaughlin, Stuart
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The BAR Domain Superfamily: Membrane-Molding Macromolecules [PDF]
Cell, 2009 Membrane-shaping proteins of the BAR domain superfamily are determinants of organelle biogenesis, membrane trafficking, cell division, and cell migration. An upsurge of research now reveals new principles of BAR domain-mediated membrane remodeling, enhancing our understanding of membrane curvature-mediated information processing.
Frost, Adam +2 more
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BAR domain competition during directional cellular migration [PDF]
Cell Cycle, 2010 While directed cellular migration facilitates the coordinated movement of cells during development and tissue repair, the precise mechanisms regulating the interplay between the extracellular environment, the actin cytoskeleton, and the overlying plasma membrane remain inadequately understood.
Gabriel A, Quiñones, Anthony E, Oro
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PLoS Genetics, 2021 Polarized hyphal growth of filamentous pathogenic fungi is an essential event for host penetration and colonization. The long-range early endosomal trafficking during hyphal growth is crucial for nutrient uptake, sensing of host-specific cues, and ...
Manisha Sinha +6 more
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Membrane sculpting by F-BAR domains studied by molecular dynamics simulations. [PDF]
PLoS Computational Biology, 2013 Interplay between cellular membranes and their peripheral proteins drives many processes in eukaryotic cells. Proteins of the Bin/Amphiphysin/Rvs (BAR) domain family, in particular, play a role in cellular morphogenesis, for example curving planar ...
Hang Yu, Klaus Schulten
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Timelike Virtual Compton Scattering from Electron-Positron Radiative Annihilation [PDF]
, 2009 We propose measurements of the deeply virtual Compton amplitude (DVCS), gamma* to H H-bar gamma, in the timelike t = (p_{H} + p_{H-bar})^2 > 0 kinematic domain which is accessible at electron-positron colliders via the radiative annihilation process e+ e-
Andrei Afanasev +5 more
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