Butallylonal 1,4-dioxane hemisolvate [PDF]
Acta Crystallographica Section E, 2010The asymmetric unit of the title compound [systematic name: 5-(1-bromoprop-2-en-1-yl)-5-sec-butylpyrimidine-2,4,6-trione 1,4-dioxane hemisolvate], C11H15BrN2O3·0.5C4H8O2, contains one half-molecule of 1,4-dioxane and one molecule of butallylonal,
Ulrich J. Griesser+2 more
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N,N-Diethylanilinium 2,4-dioxo-5-(2,4,6-trinitrophenyl)-1,2,3,4-tetrahydropyrimidin-6-olate [PDF]
Acta Crystallographica Section E, 2011In the crystal structure of the title molecular salt, C10H16N+·C10H4N5O9−, the components are linked through a N—H...O hydrogen bonds. R22(8) ring motifs are formed between inversion-related barbiturate residues.
Manickam Buvaneswari+1 more
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N,N-Diethyl-2-hydroxyethanaminium 2,6-dioxo-5-(2,4,6-trinitrophenyl)-1,2,3,6-tetrahydropyrimidin-4-olate dihydrate [PDF]
Acta Crystallographica Section E, 2011In the title molecular salt, C6H16NO+·C10H4N5O9−·2H2O, which crystallizes as a dihydrate, O—H...O hydrogen bonds link the barbiturate anion, the ethanaminium cation and the water molecules of crystallization.
Manickam Buvaneswari+1 more
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Trimethylammonium 2,6-dioxo-5-(2,4,6-trinitrophenyl)-1,2,3,6-tetrahydropyrimidin-4-olate [PDF]
Acta Crystallographica Section E, 2012In the title barbiturate salt (trivial name: trimethylammonium 2,4,6-trinitrophenylbarbiturate), C3H10N+·C10H4N5O9−, the asymmetric unit contains two sets of anion–cation moieties.
D. Kalaivani+2 more
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The thermodynamics of general and local anesthesia [PDF]
Biophys. J. 2014, 106: 2143-2156, 2014General anesthetics are known to cause depression of the freezing point of transitions in biomembranes. This is a consequence of ideal mixing of the anesthetic drugs in the membrane fluid phase and exclusion from the solid phase. Such a generic law provides physical justification of the famous Meyer-Overton rule.
Graesboll, Kaare+2 more
arxiv +4 more sources
Sleep disorders related to index and comorbid mental disorders and psychotropic drugs [PDF]
Annals of General Psychiatry, 2023Purpose Mental disorders positively associate with sleep disorders. This study will explore the moderating influence of comorbid mental disorders and whether selected psychotropic drugs correlate with sleep disorders after adjusting for mental disorders.
Ray M. Merrill+2 more
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The Sensitivity of Structure to Ionic Radius and Reaction Stoichiometry: A Crystallographic Study of Metal Coordination and Hydrogen Bonding in Barbiturate Complexes of All Five Alkali Metals Li–Cs [PDF]
MoleculesA systematic study has been conducted on barbiturate complexes of all five alkali metals, Li–Cs, prepared from metal carbonates or hydroxides in an aqueous solution without other potential ligands present, varying the stoichiometric ratio of metal ion to
William Clegg, Gary S. Nichol
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Efficacy and safety of intravenous thiamylal in sedation for colonoscopy in children. [PDF]
DEN OpenAbstract Objectives Since a standard sedation protocol for pediatric colonoscopy (CS) has not been established, evidence on optimal sedative agents is needed. This study aimed to evaluate the efficacy and safety of thiamylal in sedation for pediatric CS compared to midazolam.
Ozaka S+12 more
europepmc +2 more sources
Parkinson’s disease (PD) is one of the most common neurodegenerative disorders, and is caused by the death of dopamine neurons and neuroinflammation in the striatum and substantia nigra.
Seulah Lee+11 more
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