Results 1 to 10 of about 35,038 (278)

Efficacy of Step-down Infusion Method of a Novel Barbiturate Therapy for Severe Subarachnoid Hemorrhage with Intracerebral Hematoma [PDF]

Neurologia Medico-Chirurgica
Currently, there is no effective treatment for elevated intracranial pressure in the acute phase of subarachnoid hemorrhage. Recently, we developed “step-down infusion of barbiturate,” a therapeutic strategy for severe traumatic brain injury, which ...
Jin KIKUCHI, Yu HASEGAWA, Sosho KAJIWARA, Yusuke OTSU, Tetsuya NEGOTO, Kimihiko ORITO, Osamu TAKASU, Masaru HIROHATA, Motohiro MORIOKA   +8 more
doaj   +2 more sources

Sodium Amytal – No Longer Prescribed, but Still Relevant (And Dangerous!) [PDF]

BJPsych Open
Aims: Sodium amytal is a barbiturate medication, first synthesised in Germany in the 1920s to treat anxiety and sleep disorders; as well as being used as an anaesthetic.
Conor Brown
doaj   +2 more sources

Barbiturates and fractures. [PDF]

BMJ, 1977
Thelma B. Dunn
openalex   +4 more sources

Anti-Inflammatory Effects of the Novel Barbiturate Derivative MHY2699 in an MPTP-Induced Mouse Model of Parkinson’s Disease

Antioxidants, 2021
Parkinson’s disease (PD) is one of the most common neurodegenerative disorders, and is caused by the death of dopamine neurons and neuroinflammation in the striatum and substantia nigra.
Seulah Lee, Yeon Ji Suh, Yujeong Lee, Seonguk Yang, Dong Geun Hong, Dinakaran Thirumalai, Seung-Cheol Chang, Ki Wung Chung, Young-Suk Jung, Hyung Ryong Moon, Hae Young Chung, Jaewon Lee   +11 more
doaj   +1 more source

Cocrystal of Codeine and Cyclopentobarbital

Molbank, 2023
The two-component compound formed by codeine and cyclopentobarbital was produced using grinding techniques and through evaporation from alcoholic solutions.
Thomas Gelbrich, Jascha Schinke, Ulrich J. Griesser   +2 more
doaj   +1 more source

A novel step‐down infusion method of barbiturate therapy: Its safety and effectiveness for intracranial pressure control

Pharmacology Research & Perspectives, 2021
Intracranial pressure (ICP) has to be maintained quite constant, because increased ICP caused by cerebrovascular disease and head trauma is fatal. Although controlling ICP is clinically critical, only few therapeutic methods are currently available ...
Yukako Yamakawa, Motohiro Morioka, Tetsuya Negoto, Kimihiko Orito, Munetake Yoshitomi, Yukihiko Nakamura, Nobuyuki Takeshige, Masafumi Yamamoto, Yasuharu Takeuchi, Kazutaka Oda, Hirofumi Jono, Hideyuki Saito   +11 more
doaj   +1 more source

Narcotics Addiction and Its Treatment [PDF]

, 1957
The ongoing mythologizing of the poet in both criticism and, as recently in a play produced by Wasa teater (Vasa), is reductive, and needs to be confronted.
Winick, Charles
core   +4 more sources

Survival after pentobarbitone overdose confirmed through Prescription, Recreational and Illicit Substance Evaluation (PRISE) programme in Australia

Forensic Sciences Research, 2021
Deaths caused by barbiturate overdoses have increased in the past decade, especially as a result of suicide attempts. Pentobarbitone is a central nervous system depressant used for sedation and euthanasia in veterinary medicine.
Thanjira Jiranantakan, Sarah Ritchie, Cristy Rowe, Jason Tran, Catherine McDonald, Santiago Vazquez, Robin Auld, Jared Brown   +7 more
doaj   +1 more source

Combination of antiseizure medications phenobarbital, ketamine, and midazolam reduces soman‐induced epileptogenesis and brain pathology in rats

Epilepsia Open, 2021
Objective Cholinergic‐induced status epilepticus (SE) is associated with a loss of synaptic gamma‐aminobutyric acid A receptors (GABAAR) and an increase in N‐methyl‐D‐aspartate receptors (NMDAR) and amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid ...
Lucille A. Lumley, Brenda Marrero‐Rosado, Franco Rossetti, Caroline R. Schultz, Michael F. Stone, Jerome Niquet, Claude G. Wasterlain   +6 more
doaj   +1 more source

Supramolecular Assemblies of Melamine-2-Thiobarbiturate and Melamine-Barbiturate-2-Thiobarbiturate: Experimental and Theoretical Studies

Crystals, 2023
In this work, we considered the formation of supramolecular assemblies of melamine-thiobarbiturate and melamine-barbiturate-thiobarbiturate. It is known that thiobarbituric acid can form many tautomers, as well as different motifs due to the change of C2=
Ivan V. Moskalenko, Vladimir V. Shilovskikh, Pavel V. Nesterov, Alexander S. Novikov, Malika Omarova, Roman V. Sadovnichii, Vladislav V. Gurzhiy, Nikita D. Orekhov, Ekaterina V. Skorb   +8 more
doaj   +1 more source