Results 11 to 20 of about 13,750 (173)

Medicines for Anxiety: A Hundred Years of Tranquillity and More to Come? [PDF]

Hum Psychopharmacol
Human Psychopharmacology: Clinical and Experimental, Volume 41, Issue 2, March 2026.
Nutt D.
europepmc   +2 more sources

Evaluation of Potentially Inappropriate Medications Prescribed to Older Adults Upon Emergency Department Discharge. [PDF]

Acad Emerg Med
ABSTRACT Background Older adults are susceptible to adverse drug effects due to age‐related changes, a higher prevalence of comorbidities, and complexities in medication management. Nearly half of geriatric patients are prescribed at least one new medication at ED discharge.
Schowe J, North AM, Schuchter K, Hunold KM, Rozycki E.   +4 more
europepmc   +2 more sources

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Butallylonal 1,4-dioxane hemisolvate

Acta Crystallographica Section E, 2010
The asymmetric unit of the title compound [systematic name: 5-(1-bromoprop-2-en-1-yl)-5-sec-butylpyrimidine-2,4,6-trione 1,4-dioxane hemisolvate], C11H15BrN2O3·0.5C4H8O2, contains one half-molecule of 1,4-dioxane and one molecule of butallylonal,
Ulrich J. Griesser, Denise Rossi, Thomas Gelbrich   +2 more
doaj   +1 more source

Crystal structure of the α-racemate of methohexital

Acta Crystallographica Section E: Crystallographic Communications, 2015
Molecules of the title compound, C14H18N2O3 [systematic name: 5-allyl-5-(hex-3-yn-2-yl)-1-methylpyrimidine-2,4,6(1H,3H,5H)-trione in the (RbSh)/(SbRh) racemic form], are connected by mutual N—H...O=C hydrogen bonds in which the carbonyl group at the 2 ...
Thomas Gelbrich, Ulrich J. Griesser
doaj   +1 more source

Novel Barbiturate-Nitrate Compounds Inhibit the Upregulation of Matrix Metalloproteinase-9 Gene Expression in Intestinal Inflammation through a cGMP-Mediated Pathway

Biomolecules, 2020
Matrix metalloproteinase-9 is upregulated in inflammatory bowel disease. Barbiturate nitrate hybrid compounds have been designed to inhibit MMP secretion and enzyme activity.
Shane O’Sullivan, Jun Wang, Marek W. Radomski, John F. Gilmer, Carlos Medina   +4 more
doaj   +1 more source

Quantitative burst suppression on serial intermittent EEG in refractory status epilepticus

Clinical Neurophysiology Practice, 2021
Objectives: In refractory status epilepticus (RSE), the optimal degree of suppression (EEG burst suppression or merely suppressing seizures) remains unknown.
Joseph Peedicail, Neil Mehdiratta, Shenghua Zhu, Paulina Nedjadrasul, Marcus C. Ng   +4 more
doaj   +1 more source

Crystal structure and biological evaluation of 4-methylmorpholin-4-ium 1,3-dimethyl-2,6-dioxo-5-(2,4,6-trinitrophenyl)-1,2,3,6-tetrahydropyrimidin-4-olate

Acta Crystallographica Section E: Crystallographic Communications, 2015
The title molecular salt, C5H12NO+·C12H8N5O9− [common name: 4-methylmorpholin-4-ium 1,3-dimethyl-5-(2,4,6-trinitrophenyl)barbiturate], possesses noticeable anticonvulsant and hypnotic activity.
Jeganathan Gomathi, Doraisamyraja Kalaivani   +1 more
doaj   +1 more source

Delayed post−hypoxic leukoencephalopathy following barbiturate overdose: A case report

Journal of Acute Disease, 2022
Rationale: Delayed post-hypoxic leukoencephalopathy (DPHL) is usually an overlooked condition, which arises as a result of a multitude of reversible and irreversible conditions.
Arshi Syal, Samiksha Gupta, Monica Gupta, Gautam Jesrani, Yajur Arya   +4 more
doaj   +1 more source

Barbiturat dan Obat Pelumpuh Otot: Masih Bermanfaat untuk Menangani Hipertensi Intrakranial?

Jurnal Neuroanestesi Indonesia, 2013
Hipertensi intrakranial dapat menyebabkan cedera otak sekunder dan meningkatkan morbiditas serta mortalitas. Untuk mempertahankan tekanan intrakranial agar senantiasa dalam batas normal, maka cairan serebrospinal dan darah mempunyai kemampuan untuk ...
M. Sofyan Harahap
doaj   +1 more source