Results 21 to 30 of about 35,038 (278)

Evaluation of feline renal perfusion with contrast-enhanced ultrasonography and scintigraphy [PDF]

, 2016
Contrast-enhanced ultrasound (CEUS) is an emerging technique to evaluate tissue perfusion. Promising results have been obtained in the evaluation of renal perfusion in health and disease, both in human and veterinary medicine. Renal scintigraphy using Tc-
Bosmans, Tim, Dobbeleir, André, Duchateau, Luc, Hesta, Myriam, Lybaert, Lien, Peremans, Kathelijne, Saunders, Jimmy, Stock, Emmelie, Vandermeulen, Eva, Vanderperren, Katrien   +9 more
core   +4 more sources

Therapeutic profile of antiepileptics in patients from the Wilaya of Batna. A retrospective study on 106 cases. [PDF]

Batna Journal of Medical Sciences
Introduction. Therapeutic monitoring of conventional antiepileptic drugs is an essential approach to optimize the management of epileptic patients.
Soumaya BOUDJEMAA, Ikram BOUDJELLAL, Rayane BOUZID, Said NADJI, Ines BOULEKROUNE, Mohamed Tahar BENMOUSSA, Rafika LAICHE, Chahrazed RAJAI, Maha REZKI, Samira BOUKHERBECHE   +9 more
doaj   +1 more source

Delayed post−hypoxic leukoencephalopathy following barbiturate overdose: A case report

Journal of Acute Disease, 2022
Rationale: Delayed post-hypoxic leukoencephalopathy (DPHL) is usually an overlooked condition, which arises as a result of a multitude of reversible and irreversible conditions.
Arshi Syal, Samiksha Gupta, Monica Gupta, Gautam Jesrani, Yajur Arya   +4 more
doaj   +1 more source

Crystal structure of the α-racemate of methohexital

Acta Crystallographica Section E: Crystallographic Communications, 2015
Molecules of the title compound, C14H18N2O3 [systematic name: 5-allyl-5-(hex-3-yn-2-yl)-1-methylpyrimidine-2,4,6(1H,3H,5H)-trione in the (RbSh)/(SbRh) racemic form], are connected by mutual N—H...O=C hydrogen bonds in which the carbonyl group at the 2 ...
Thomas Gelbrich, Ulrich J. Griesser
doaj   +1 more source

Crystal structure and biological evaluation of 4-methylmorpholin-4-ium 1,3-dimethyl-2,6-dioxo-5-(2,4,6-trinitrophenyl)-1,2,3,6-tetrahydropyrimidin-4-olate

Acta Crystallographica Section E: Crystallographic Communications, 2015
The title molecular salt, C5H12NO+·C12H8N5O9− [common name: 4-methylmorpholin-4-ium 1,3-dimethyl-5-(2,4,6-trinitrophenyl)barbiturate], possesses noticeable anticonvulsant and hypnotic activity.
Jeganathan Gomathi, Doraisamyraja Kalaivani   +1 more
doaj   +1 more source

Barbiturate-refractory epilepsy: safe schedule for therapeutic substitution

Arquivos de Neuro-Psiquiatria, 1986
Barbiturates are considered first line antiepileptic drugs in third world countries due to traditional and economic reasons. This prospective uncontrolled study of 52 patients aged 15 to 64 years (mean 24) demonstrates that patients who become refractory
Ana Maria Gorz, Carlos E. S. Silvado, Paulo Rogério M. Bittencourt   +2 more
doaj   +1 more source

Enamine Barbiturates and Thiobarbiturates as a New Class of Bacterial Urease Inhibitors

Applied Sciences, 2020
Urease is a therapeutic target associated with several important diseases and health problems. Based on our previous work on the inhibition of glucosidase and other enzymes and exploiting the privileged structure assigned to the (thio)barbiturate ...
M. Ali, Assem Barakat, Ayman El-Faham, Abdullah Mohammed Al-Majid, Sammer Yousuf, Sajda Ashraf, Zaheer Ul-Haq, M. Iqbal Choudhary, Beatriz G. de la Torre, Fernando Albericio   +9 more
doaj   +1 more source

Neuroactive steroids in depression and anxiety disorders: Clinical studies [PDF]

, 2006
Certain neuroactive steroids modulate ligand-gated ion channels via non-genomic mechanisms. Especially 3 alpha-reduced pregnane steroids are potent positive allosteric modulators of the gamma-aminobutyric acid type A (GABA(A)) receptor.
Akwa Y, Baghai TC, Baker ER, Barrett-Connor E, Bicikova M, Bitran D, Bloch M, Brambilla F, Brambilla F, Brambilla F, Cornelius Schüle, Crawley JN, Dalton K, Daniela Eser, Dennerstein L, Dong E, Elena Romeo, Eser D, Evans RM, Fabian TJ, Freeman E, Freeman EW, Friess E, George MS, Goodyer IM, Guidotti A, Heydari B, Heydary B, Kita A, Koszycki D, Lawrie TA, Maayan R, Magill PJ, Majewska MD, Majewska MD, Majewska MD, Matsumoto K, Meieran SE, Melchior CL, Melchior CL, Mensah-Nyagan AG, Mienville JM, Monnet FP, Padberg F, Papadopoulos V, Paul SM, Purdy RH, Rainer Rupprecht, Reddy DS, Reddy DS, Reddy DS, Rodgers RJ, Romeo E, Rupprecht R, Rupprecht R, Schmidt PJ, Schule C, Schule C, Semeniuk T, Serra M, Serra M, Strohle A, Strohle A, Strohle A, Strous RD, Takebayashi M, Thomas C. Baghai, Tollefson GD, Trauger JW, Urani A, Uzunov DP, Uzunova V, Uzunova V, Uzunova V, Vanselow W, Wieland S, Wolkowitz OM, Wolkowitz OM, Wu FS, Zwanzger P   +79 more
core   +1 more source

Update on medication-overuse headache and its treatment [PDF]

, 2015
OPINION STATEMENT: Medication-overuse headache-i.e., a too-frequent consumption of acute headache medications leading to increased headache frequency and reduced effectiveness of acute and preventive treatments-is a serious medical condition whose ...
Giamberardino MA, MARTELLETTI, Paolo, Mitsikostas DD   +2 more
core   +1 more source

Voltage imaging of waking mouse cortex reveals emergence of critical neuronal dynamics. [PDF]

, 2014
Complex cognitive processes require neuronal activity to be coordinated across multiple scales, ranging from local microcircuits to cortex-wide networks.
Fagerholm, ED, Knöpfel, T, Leech, R, Mutoh, H, Scott, G, Sharp, DJ, Shew, WL   +6 more
core   +2 more sources