Results 21 to 30 of about 34,333 (275)
Crystal structure of the α-racemate of methohexital
Acta Crystallographica Section E: Crystallographic Communications, 2015 Molecules of the title compound, C14H18N2O3 [systematic name: 5-allyl-5-(hex-3-yn-2-yl)-1-methylpyrimidine-2,4,6(1H,3H,5H)-trione in the (RbSh)/(SbRh) racemic form], are connected by mutual N—H...O=C hydrogen bonds in which the carbonyl group at the 2 ...
Thomas Gelbrich, Ulrich J. Griesser
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Acta Crystallographica Section E: Crystallographic Communications, 2015 The title molecular salt, C5H12NO+·C12H8N5O9− [common name: 4-methylmorpholin-4-ium 1,3-dimethyl-5-(2,4,6-trinitrophenyl)barbiturate], possesses noticeable anticonvulsant and hypnotic activity.
Jeganathan Gomathi +1 more
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Update on medication-overuse headache and its treatment [PDF]
, 2015 OPINION STATEMENT: Medication-overuse headache-i.e., a too-frequent consumption of acute headache medications leading to increased headache frequency and reduced effectiveness of acute and preventive treatments-is a serious medical condition whose ...
Giamberardino MA +2 more
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Barbiturate-refractory epilepsy: safe schedule for therapeutic substitution
Arquivos de Neuro-Psiquiatria, 1986 Barbiturates are considered first line antiepileptic drugs in third world countries due to traditional and economic reasons. This prospective uncontrolled study of 52 patients aged 15 to 64 years (mean 24) demonstrates that patients who become refractory
Ana Maria Gorz +2 more
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Enamine Barbiturates and Thiobarbiturates as a New Class of Bacterial Urease Inhibitors
Applied Sciences, 2020 Urease is a therapeutic target associated with several important diseases and health problems. Based on our previous work on the inhibition of glucosidase and other enzymes and exploiting the privileged structure assigned to the (thio)barbiturate ...
M. Ali +9 more
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Neonatal abstinence syndrome: Pharmacologic strategies for the mother and infant. [PDF]
, 2016 Opioid use in pregnancy has increased dramatically over the past decade. Since prenatal opioid use is associated with numerous obstetrical and neonatal complications, this now has become a major public health problem.
Davis, Jonathan M. +2 more
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N,N-Diethylanilinium 2,4-dioxo-5-(2,4,6-trinitrophenyl)-1,2,3,4-tetrahydropyrimidin-6-olate
Acta Crystallographica Section E, 2011 In the crystal structure of the title molecular salt, C10H16N+·C10H4N5O9−, the components are linked through a N—H...O hydrogen bonds. R22(8) ring motifs are formed between inversion-related barbiturate residues.
Manickam Buvaneswari +1 more
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Sleep disorders related to index and comorbid mental disorders and psychotropic drugs
Annals of General Psychiatry, 2023 Purpose Mental disorders positively associate with sleep disorders. This study will explore the moderating influence of comorbid mental disorders and whether selected psychotropic drugs correlate with sleep disorders after adjusting for mental disorders.
Ray M. Merrill +2 more
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5,5-Dihydroxybarbituric acid 1,4-dioxane hemisolvate
Acta Crystallographica Section E, 2010 The asymmetric unit of the title compound,, C4H4N2O5·0.5C4H8O2, contains one molecule of 5,5-dihydroxybarbituric acid with a nearly planar barbiturate ring and half a molecule of 1,4-dioxane.
Thomas Gelbrich +2 more
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ChemElectroChem, 2023 A highly efficient, fast, catalyst‐free, and atom economical method was developed for the synthesis of 5‐benzylidenebarbiturates. Thus, reacting barbituric acid and aldehydes in water as a green solvent under electrochemical conditions afforded the ...
Dr. Yara S. El‐Dash +3 more
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