Results 71 to 80 of about 34,094 (267)

The human photosensitive epilepsy model for clinical proof‐of‐principle trials of novel antiseizure medications: 2. Analysis of drug trials and predictive value of the model

Epilepsia, EarlyView.
Abstract Clinical development of novel antiseizure medications (ASMs) would benefit from an early proof of principle (POP) model. The photosensitivity model, which uses the photoparoxysmal electroencephalographic response (PPR) as a surrogate of seizures, is currently the only human model that allows POP trials of investigational compounds after a ...
Wolfgang Löscher, Dorothée Kasteleijn‐Nolst Trenité   +1 more
wiley   +1 more source

Drugs analysis using latex agglutination tests

Тонкие химические технологии, 2011
The method of latex agglutination was used to develop express diagnostics of the most extended groups of drugs (opiates, cannabinoides and barbiturates).
N. М. Solodukhina, Т. V. Abramenko, М. А. Myagkova, I. А. Gritskova   +3 more
doaj  

Status epilepticus in older adults: A critical review

Epilepsia, EarlyView.
Abstract Older adults (≥60 years of age) have the highest incidence of status epilepticus (SE) among adults and experience the highest morbidity and mortality. SE incidence increases with age in adulthood. A recent study from Austria estimated an incidence of 89.6/100 000 and 67.6/100 000 person‐years adjusted for age and sex in women and men aged >60 ...
Matthew R. Woodward, Michael J. Armahizer, Tina I. Wang, Neeraj Badjatia, Emily L. Johnson, Emily J. Gilmore   +5 more
wiley   +1 more source

Graphene oxide enhances SBA-15 ability towards preconcentration as well as determination of barbiturate drug in real samples

Kuwait Journal of Science, 2019
In this study, a simple, sensitive, and high performance method was employed to extract and preconcentration of trace amount of sodium barbiturate drug by using mesoporous silica (SBA-15) modified by graphene oxide (GO).
Ali Shokuhi Rad, Ali Mirabi, Sadaf Ahmadizadeh   +2 more
doaj  

Coma Blisters

Case Reports in Dermatology, 2009
Coma blisters are lesions that occur in the setting of a variety of neurological diseases. Although most commonly associated with barbiturate overdose, they can be seen in the setting of coma due to other etiologies.
Joana Rocha, Teresa Pereira, Filipa Ventura, Fernando Pardal, Celeste Brito   +4 more
doaj   +1 more source

Response Dynamics of Entorhinal Cortex in Awake, Anesthetized, and Bulbotomized Rats. Brain Research 911(2) [PDF]

, 2001
The generation of oscillatory activity may be crucial to brain function. The coordination of individual neurons into rhythmic and coherently active populations is thought to result from interactions between excitatory and inhibitory cells mediated by ...
Ahrens, Kurt F., Freeman, Walter J.
core  

Optimizing phenobarbital dosing in critically ill patients with refractory and superrefractory status epilepticus using a population pharmacokinetic model

Epilepsia, EarlyView.
Abstract Objective Current weight‐based dosing fails to account for pharmacokinetic variability in refractory and superrefractory status epilepticus (RSE, SRSE). However, understanding pharmacokinetics in critically ill patients with varying degrees of organ dysfunction can improve both safety and efficacy.
Maximilian Stoschus, Moritz L. Schmidbauer, Johannes Starp, Stefan Kunst, Georgios Gakis, Michael Paal, Michael Vogeser, Christina Scharf‐Janssen, Uwe Liebchen, Konstantinos Dimitriadis   +9 more
wiley   +1 more source

Triethylammonium 1,3-dimethyl-5-(2,4,6-trinitrophenyl)barbiturate

Acta Crystallographica Section E, 2012
In the title molecular salt [systematic name: triethylammonium 1,3-dimethyl-2,6-dioxo-5-(2,4,6-trinitrophenyl)-1,2,3,6-tetrahydropyrimidin-4-olate], C6H16N+·C12H8N5O9−, the dihedral angle between the aromatic rings in the anion is 46 ...
Kulandaiya Rajamani, Doraisamyraja Kalaivani   +1 more
doaj   +1 more source

Nurses\u27 Alumnae Association Bulletin, May 1956 [PDF]

, 1956
Alumnae Notes Anesthesiology at Jefferson Committee Reports Digest of Alumnae Meetings Graduation Awards - 1955 Marriages Necrology New Arrivals Physical Advances at Jefferson President\u27s Message School of Nursing Report Thomas A.
Edgar, Dorothy J, Heverly, Isabelle Kevel, Prevost, Mabel C, Rake, Paul F   +3 more
core   +1 more source

Evaluation of the central activity of the ethanolic extract of Acosmium subelegans (Mohlenbr) in mice [PDF]

, 2002
The ethanolic extract (EE) of Acosmium subelegans (Mohlenbr) Yakovl (perobinha-do-campo) was tested to behavioral paradigms in mice to investigate its putative central depressant effect.
Lapa, Antonio José, Lima, Thereza Cristina Monteiro de, Vieira, Ricardo A.   +2 more
core   +2 more sources