Results 81 to 90 of about 34,333 (275)
Neuronal activity and stress differentially regulate hippocampal and hypothalamic corticotropin-releasing hormone expression in the immature rat. [PDF]
, 2000 Corticotropin-releasing hormone, a major neuromodulator of the neuroendocrine stress response, is expressed in the immature hippocampus, where it enhances glutamate receptor-mediated excitation of principal cells. Since the peptide influences hippocampal
Baram, TZ +4 more
core +1 more source
Journal of Sleep Research, EarlyView.ABSTRACT The 2019 coronavirus (COVID‐19) pandemic and associated lockdowns significantly disrupted healthcare systems, including access to pharmacological treatments such as sleep medication. This study investigated the number of first‐time dispensed hypnotic drugs during the first COVID‐19 lockdown in the Netherlands, using data from the Dutch ...
Dana M. Dijkgraaf +5 more
wiley +1 more source
Dreaming of Better Treatments: Advances in Drug Development for Sleep Medicine and Chronotherapy
Journal of Sleep Research, Volume 34, Issue 5, October 2025.ABSTRACT Throughout history, the development of new sleep medicines has been driven by progress in our understanding of the mechanisms underlying sleep. Ancient civilisations used their understanding of the sedative nature of natural herbs and compounds to induce sleep.
Brooke A. Prakash +5 more
wiley +1 more source
Triethylammonium 2,4-dinitrophenylbarbiturate
Acta Crystallographica Section E, 2009 In the title molecular salt [systematic name: triethylammonium 5-(2,4-dinitrophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-olate], C6H16N+·C10H5N4O7−, the cation and anion are linked by an N—H...O hydrogen bond.
Doraisamyraja Kalaivani +1 more
doaj +1 more source
Specialized neurocritical care, severity grade, and outcome of patients with aneurysman subarachnoid hemorrhage [PDF]
, 2018 Introduction: To evaluate the impact of specialized neurocritical care on the population admitted to a neurovascular center and on the outcome of patients with severe aneurysmal subarachnoid hemorrhage (aSAH). Methods: After exclusion of patients treated
Bjeljac, Miroslava +4 more
core
Sleep and Dreams as Reflected by Science Fiction Literature and Films—Anything to Learn From?
Journal of Sleep Research, Volume 34, Issue 5, October 2025.ABSTRACT Sleep and dreams are frequent themes in science fiction (Sci‐Fi) literature and films, often used to explore questions about consciousness, reality, technology and the human experience. Sci‐Fi authors and filmmakers utilise the enigmatic nature of sleep and dreams to blur the boundaries between reality and imagination, raising philosophical ...
Dieter Riemann +4 more
wiley +1 more source
Food Science &Nutrition, Volume 13, Issue 9, September 2025.Our study suggested that chitin and chitosan could inhibit MRGPRX2/MrgprB2‐mediated mast cells degranulation in vitro and in vivo. Chitosan showed stronger inhibition effect on MRGPRX2 activation than chitin. RNA‐seq analysis indicated that it may affect the activity of structural molecules, chromatin structural components and protein ...
Tao Jia +8 more
wiley +1 more source
Cerebral and cardiovascular effects of analgesic doses of ketamine during a target controlled general anesthesia: a prospective randomized study [PDF]
, 2017 Introduction: Ketamine is increasingly being used in various pain settings. The purpose of this study was to assess the effect of an analgesic dose of ketamine in the bispectral index (BIS), spectral edge frequency (SEF-95), density spectral array (DSA),
Araujo, A. M. +3 more
core +1 more source
Food Science &Nutrition, Volume 13, Issue 9, September 2025.In this paper, we have investigated the in vitro antioxidant as well as in vivo analgesic, anxiolytic, and antidepressant activities of the methanolic extract of Boehmeria caudata leaves, alongside a phytochemical evaluation using FT‐IR and GC‐MS analysis.
Md. Liakot Ali +9 more
wiley +1 more source