Results 151 to 160 of about 4,580,472 (190)

Plant base editing: a decade of progress and future applications. [PDF]

aBIOTECH
Zhang R, Zheng Z, Li G, Zheng X, Su L, Yuan X, Li T, Tan J, Zeng D, Zhang S, Liu J, Shen H, Chai N, Liu YG, Zhu Q.   +14 more
europepmc   +1 more source

Therapeutic base editing to generate a gain-of-function F9 variant for hemophilia B.

Blood
Baatartsogt N, Kashiwakura Y, Hiramoto T, Ito R, Sato R, Nagao Y, Naruoka H, Takata H, Hayakawa M, Batjargal K, Togashi T, Hoshino A, Shimizu T, Sato Y, Ishida T, Nureki O, Ohmori T.   +16 more
europepmc   +1 more source

Dissecting multi-gene virulence phenotypes with base editing requires consideration of target-independent mutagenesis

Newson JPM, Gawlitt S, Sundar S, Regoes RR, Beisel CL, Hardt W.   +5 more
europepmc   +1 more source

CRISPR-Cas9 DNA Base-Editing and Prime-Editing [PDF]

International Journal of Molecular Sciences, 2020
Many genetic diseases and undesirable traits are due to base-pair alterations in genomic DNA. Base-editing, the newest evolution of clustered regularly interspaced short palindromic repeats (CRISPR)-Cas-based technologies, can directly install point-mutations in cellular DNA without inducing a double-strand DNA break (DSB).
Michelle E McClements, Robert MacLaren, Mark Hassall   +2 more
exaly   +4 more sources

Some of the next articles are maybe not open access.

Related searches:

Base Editing in Progeria

New England Journal of Medicine, 2021
Extending Life Span in a Mouse Model of Progeria The Hutchinson–Gilford progeria syndrome is an autosomal dominant disease caused by a single point mutation in LMNA, which encodes the lamin A and C...
Jin-Soo, Kim, Maria, Eriksson
openaire   +2 more sources

A Review on Advanced CRISPR-Based Genome-Editing Tools: Base Editing and Prime Editing

Molecular Biotechnology, 2022
In the field of medicine, it is axiomatic that the need of a precise gene-editing tool is critical to employ therapeutic approaches toward pathogenic mutations, occurring in human genome. Today we know that most of genetic defects are caused by single-base pair substitutions in genomic DNA.
Ali Saber Sichani, Maryam Ranjbar, Maryam Baneshi, Farid Torabi Zadeh, Jafar Fallahi   +4 more
openaire   +2 more sources

Symmetry-based photo-editing

Pattern Recognition, 2003
In this paper, we demonstrate how to edit digital photos based on the understanding of high-level geometric knowledge imposed upon objects in the photos. This is achieved by the correct recovery of the 3-D shape and relationships of the objects, without explicitly performing full 3-D reconstruction.
Kun Huang 0001, Wei Hong 0003, Yi Ma 0001   +2 more
openaire   +3 more sources

Base editing on the rise

Nature Biotechnology, 2017
Research on base editing leads to new enzymes, genome-wide specificity measurements, and edited plants and animals.
openaire   +2 more sources

Cytosine Base Editing in Bacteria

2023
Base editing is a new genome editing technology that enables DNA base mutations without requiring double-stranded DNA backbone cleavage or a donor template. It has been widely used for genome engineering of eukaryotic and prokaryotic microorganisms.
Ye, Liu, Yang, Liu, Ping, Zheng, Yu, Wang, Meng, Wang   +4 more
openaire   +2 more sources

Current knowledge of base editing and prime editing

Molekulârnaâ biologiâ
Modern genetic engineering technologies, such as base editing (BE) and prime editing (PE), have proven to be effective and reliable genome editing tools that do not require the introduction of double-strand breaks in DNA and the presence of donor templates.
O A, Averina, S A, Kuznetsova, O A, Permyakov, P V, Sergiev   +3 more
openaire   +2 more sources