Results 141 to 150 of about 4,580,472 (190)

In vivo adenine base editing of mutant Galc gene ameliorates Krabbe disease progression. [PDF]

Genome Med
Nam BG, Seo JH, Hong SA, Kim JH, Kang M, Notario GR, Hong Y, Cho S, Bae S, Cho SR.   +9 more
europepmc   +1 more source

sgRNA amount is a limiting factor in adenine base editing using RNA LNPs. [PDF]

Mol Ther Nucleic Acids
Birkenshaw A, Thomson T, Truong MP, Komaki Y, Ramsden N, Timpano A, Huang C, Blakney AK, Kurek DZ, Kulkarni J, Ross CJD.   +10 more
europepmc   +1 more source

Advances in CRISPR Base Editing: From Molecular Evolution to Therapeutic Applications in Genomic Medicine. [PDF]

J Cell Mol Med
Aliciaslan M, Erbasan E, Erendor F, Sanlioglu S.   +3 more
europepmc   +1 more source

Precise Generation of High-β-Carotene Watermelon via Visualised Base Editing. [PDF]

Plant Biotechnol J
Tian S, Zhang X, Wang J, Guo S, Zhang H, Gong G, Ren Y, Li M, Yu Y, Liao S, Xu Y, Zhang J.   +11 more
europepmc   +1 more source

Base editing of Artemis mutations ex vivo sheds light on gene therapy for Artemis-deficient SCID. [PDF]

Adv Biotechnol (Singap)
Huang Z, Cai Z, Yan P, Hu Y, Wang Y, Zhou G, Deng L, Wang X, Li Z, Chen W, Tao X, Xu A, Yuan S.   +12 more
europepmc   +1 more source

Multiplexed CRISPR base editing enables pulse-activated irreversible biocontainment of engineered bacteria. [PDF]

Nucleic Acids Res
Cho SW, Kim T, Yang J, Byun G, Seo SW.
europepmc   +1 more source

Ablation of PKCα Phosphorylation by CRISPR-Cas9 Base Editing Rescues Heart Failure. [PDF]

Circ Res
Tadokoro T, Li H, Gan P, Xu Z, Tan W, Alzhanov D, Sánchez-Ortiz E, McAnally JR, Guo L, Xu L, Ruan P, Liu N, Olson EN.   +12 more
europepmc   +1 more source

In vivo base editing rescues ADPKD in a humanized mouse model. [PDF]

Nat Commun
Cheng AS, Li LX, Zhou JX, Harris PC, Calvet JP, Li X.   +5 more
europepmc   +1 more source

Targeted mutagenesis and base editing using engineered <i>Brevibacillus laterosporus</i> Cas9 with expanded target scope in rice. [PDF]

Plant Biotechnol (Tokyo)
Negishi K, Nishimasu H, Nureki O, Toki S, Endo M.   +4 more
europepmc   +1 more source

A self-iterative orthogonal base-editing platform enables multiplex N-to-N diversification and genome-scale functional screening in Escherichia coli. [PDF]

Nucleic Acids Res
Fan X, Liang L, Wang H, Liu G, Tan H, Zhang F, Liu L, Liu R.   +7 more
europepmc   +1 more source