Results 121 to 130 of about 4,580,472 (190)

Therapeutic base editing alleviates restrictive cardiomyopathy. [PDF]

Cell Rep Med
Chang C, Zhang X, Fan X, Chang Y, Feng Y, Li G, Jia H, Wen S, Zhang N, Hua X, Cui H, Chen X, Song J, Chang X.   +13 more
europepmc   +1 more source

Overcoming the cytosine base editing barrier: Virus-like particles with uracil-DNA glycosylase inhibition unlocking the clinical potential. [PDF]

Clin Transl Med
Wu Y, Zhu X, Zhu J, Chen J, Hong J.
europepmc   +1 more source

Precision base-editing of the cryptic 3' acceptor site to correct the RNA splicing defect of β⁶⁵⁴-thalassemia. [PDF]

Mol Biomed
Lu D, Gong X, Guo X, Cai Q, Li W, Chen Y, Li D, Zeng F.   +7 more
europepmc   +1 more source

Base editing rescues a hereditary motor neuron disease in mouse and patient-derived iPSC organoid models. [PDF]

Mol Ther Adv
Imamura K, Yoshioka S, Kamizato K, Oki R, Hioki H, Tsukita K, Inoue I, Shimizu R, Takiguchi M, Sakasai T, Okusa A, Shibukawa R, Niki T, Sakurai S, Okunomiya T, Kondo T, Kato T, Miyanohara A, Kakinohana M, Yamamoto T, Marsala M, Nishida K, Izumi Y, Inoue H.   +23 more
europepmc   +1 more source

Boosting cytosine base editing in potato through synergistic optimization. [PDF]

Hortic Res
Zhang Y, Zhang L, Deng J, Zhou H, Xiao E, Zhu G, Zhang C, Chen K.   +7 more
europepmc   +1 more source

Pharmacological readthrough and base editing for <i>ANK1</i> nonsense mutations in an erythroid model of hereditary spherocytosis. [PDF]

Mol Ther Nucleic Acids
Li S, Li J, Shi W, Nie Z, Zhang S, Ding X, Hu J, Li P, Xie X.   +8 more
europepmc   +1 more source

BASELINE: a CRISPR base editing platform for mammalian-scale single-cell lineage tracing. [PDF]

Nucleic Acids Res
Winter E, Emiliani F, Cook A, Abderrahim A, McKenna A.   +4 more
europepmc   +1 more source

BEstimate: a computational tool for the design and interpretation of CRISPR base editing experiments. [PDF]

Genome Biol
Dinçer C, Fussing B, Garnett MJ, Coelho MA.   +3 more
europepmc   +1 more source

AI-designed OpenCRISPR-1 performs robust knockout, base editing, and prime editing in rice. [PDF]

New Phytol
Das P, Saha R, Panda D, Ghosh C, Avinash SP, Panda S, Baig MJ, Molla KA.   +7 more
europepmc   +1 more source

Balancing personalized medicine and scalability in base editing for phenylketonuria. [PDF]

Mol Ther Nucleic Acids
Nicosia L.
europepmc   +1 more source