Results 131 to 140 of about 4,580,472 (190)

Mutation-agnostic base editing of the progerin farnesylation site rescues Hutchinson-Gilford progeria syndrome phenotypes in neuromuscular organoids. [PDF]

Nat Commun
Kim DW, Kwon EJ, Jeon BJ, Kwon DH, Jang G, Yoon Y, Hwang Y, Lee H, Cha HJ.   +8 more
europepmc   +1 more source

Feature representation for explainable CRISPR off-target prediction and base editing efficiency. [PDF]

Front Bioinform
Hasin F, Minervini M, Mencar C, Ventrella G, Consiglio A, Orro A, Selmi T.   +6 more
europepmc   +1 more source

Come together: The BE-TILs-Efficient multiplex base editing of tumor-infiltrating lymphocytes. [PDF]

Mol Ther Oncol
Glaser V, Wagner DL, Bexte T.
europepmc   +1 more source

In vivo base editing of Chd3 rescues behavioural abnormalities in mice. [PDF]

Nature
Yang K, Li WK, Geng YX, Zhang SQ, Wu SH, Cheng YB, Wang JW, Xu ZK, Wang WX, Zhang TY, Wang PY, Yuan YT, Fan J, Wu J, Xu RC, Zhang YF, Tao GJ, Li ZH, Lin CX, Li TS, Zhang XY, Li J, Zhang R, Yang WX, Wen JS, Yang ZY, Gong L, Zeng W, Du AL, Li JS, Li F, Cheng TL, Qiu Z.   +32 more
europepmc   +1 more source

Long-term restoration of auditory function in a DFNA2 mouse model by adenine base editing. [PDF]

EMBO Mol Med
Kong Y, Zhang Y, Xie E, Li X, Peng Z, Zhang J, Zhao Y, Yuan H.   +7 more
europepmc   +1 more source

Harnessing nucleotide metabolism to control glycosylase base editing outcomes. [PDF]

Theranostics
Tao R, Li M, Fei J, Tang M, Yang Z, Hu Y, Jiao Y, Hu Z, Yao S.   +8 more
europepmc   +1 more source

Base editing and nanoparticle transfection of airway cell types essential for treatment of cystic fibrosis. [PDF]

JCI Insight
Kavanagh EW, Joynt AT, Pion AR, Eastman AC, Parr AI, Starego KL, Jain M, Shannon SR, Yoo EJ, Newby GA, Tzeng SY, Sharma N, Green JJ, Cutting GR.   +13 more
europepmc   +1 more source

Cytosine base editing of LPA in transgenic mice averts large deletions. [PDF]

Mol Ther
Chuecos MA, Park SH, Bhakta MM, Too-Chiobi U, Betancourth D, Cao M, De Giorgi M, Walkey CJ, Tiwari A, Godin B, Assini JM, Palmer DJ, Ng P, Boffa MB, Koschinsky ML, Bao G, Lagor WR.   +16 more
europepmc   +1 more source

Author Correction: Effective in vivo RNA base editing via engineered cytidine deaminase APOBECs fused with PUF proteins. [PDF]

Nat Commun
Han W, Yuan B, Fan X, Li W, Yuan Y, Zhang Y, Wang S, Shan S, Hafner M, Wang Z, Qiu Z.   +10 more
europepmc   +1 more source

In Vivo Base Editing for Neonatal Inborn Errors of Metabolism: Clinical Progress, N-of-1 Therapy, and the Ethics of Bespoke Genetic Medicine. [PDF]

Cureus
Li OM, Li Y, Li SXT.
europepmc   +1 more source