Results 261 to 270 of about 967,825 (378)

Base excision repair and double strand break repair cooperate to modulate the formation of unrepaired double strand breaks in mouse brain. [PDF]

Nat Commun
Polyzos AA, Cheong A, Yoo JH, Blagec L, Toprani SM, Nagel ZD, McMurray CT.   +6 more
europepmc   +1 more source

Base excision repair of the N-(2-deoxy-d-erythro-pentofuranosyl)-urea lesion by the hNEIL1 glycosylase. [PDF]

Nucleic Acids Res, 2023
Tomar R, Minko IG, Sharma P, Kellum AH, Lei L, Harp JM, Iverson TM, Lloyd RS, Egli M, Stone MP.   +9 more
europepmc   +1 more source

Quantitation of intracellular NAD(P)H can monitor an imbalance of DNA single strand break repair in base excision repair deficient cells in real time [PDF]

, 2003
Jun Nakamura
openalex   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Effect of kynurenic acid on enzymatic activity of the DNA base excision repair pathway in specific areas of the sheep brain. [PDF]

Sci Rep
Młotkowska P, Misztal T, Kowalczyk P, Marciniak E.   +3 more
europepmc   +1 more source

A mechanism for the exclusion of low-fidelity human Y-family DNA polymerases from base excision repair [PDF]

, 2003
Lajos Haracska, Louise Prakash, Satya Prakash   +2 more
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Unfilled gaps by polβ lead to aberrant ligation by LIG1 at the downstream steps of base excision repair pathway. [PDF]

Nucleic Acids Res
Gulkis M, Martinez E, Almohdar D, Çağlayan M.   +3 more
europepmc   +1 more source

Single-Nucleotide Polymorphisms in Base-Excision Repair-Related Genes Involved in the Risk of an Occurrence of Non-Alcoholic Fatty Liver Disease. [PDF]

Int J Mol Sci, 2023
Ziółkowska S, Kosmalski M, Kołodziej Ł, Jabłkowska A, Szemraj JZ, Pietras T, Jabłkowski M, Czarny PL.   +7 more
europepmc   +1 more source

Oxidative DNA damage is epigenetic by regulating gene transcription via base excision repair

Proceedings of the National Academy of Sciences of the United States of America, 2016
A. Fleming, Yun Ding, C. Burrows
semanticscholar   +1 more source