Results 21 to 30 of about 112,601 (234)

Research Advances on Base Excision Repair Factor SmuG1 and Tumor

Zhongliu Fangzhi Yanjiu, 2019
Tumor is one of the diseases that seriously threaten human health. With the deepening of research, it is found that the role of DNA damage in the occurrence and development of tumors is more and more important.
ZHENG Lijiao, PENG Dongxian, WANG Guanfeng, HUANG Jie   +3 more
doaj   +1 more source

DNA demethylation pathways: Additional players and regulators. [PDF]

, 2017
DNA demethylation can occur passively by "dilution" of methylation marks by DNA replication, or actively and independently of DNA replication. Direct conversion of 5-methylcytosine (5mC) to cytosine (C), as originally proposed, does not occur.
Abdouni, An, Arakawa, Barreto, Bellon, Bhutani, Bhutani, Blaschke, Boorstein, Bourc'his, Bransteitter, Brown, Buganim, Chakraborty, Chen, Chen, Chen, Chowdhury, Chung, Cortazar, Cortellino, Costa, Dai, Dai, Dang, Dawlaty, Dawlaty, Dawlaty, Delhommeau, Doege, Dominguez, Engel, Fortini, Foshay, Fousteri, Franchini, Fritz, Fritz, Gao, Ge, Gehring, Gjini, Grin, Gu, Guo, Guo, Habib, Hajkova, Hashimoto, Hashimoto, Hashimoto, Hashimoto, Hata, Hata, He, Henson, Hildrestrand, Hogenbirk, Hollander, Hon, Hu, Hu, Iiams, Inoue, Iqbal, Ito, Iyer, Jin, Jin, Jiricny, Jones, Kagiwada, Kaneda, Kellinger, Ko, Kosmider, Kou, Kriaucionis, Krokan, Kumar, Langemeijer, Larijani, Laukka, Lenz, Li, Li, Li, Li, Liu, Liutkeviciute, Lorsbach, Lu, Ma, Maiti, Maiti, Marusawa, Mayer, Moran-Crusio, Muller, Muramatsu, Muramatsu, Nabel, Nakanishi, Nemec, Niehrs, Nilsen, Ohno, Okano, Ooi, Pais, Pastor, Perez, Petersen-Mahrt, Pfaffeneder, Pollard, Popp, Rai, Raiber, Ramiro, Rangam, Revy, Rommel, Rusmintratip, Sabag, Sajadian, Santos, Schiesser, Schiesser, Schmitz, Schomacher, Sciacovelli, Sejersted, Shen, Shen, Shibutani, Shimamoto, Shimoda, Silverman, Spruijt, Stier, Szulik, Tahiliani, Tamura, Tan, Vartanian, Verdine, Wagner, Wang, Weber, Wijesinghe, Wojciechowski, Wu, Xiao, Xu, Xu, Xu, Xue, Yamazaki, Yin, Young, Zanotti, Zhao, Zhu   +162 more
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Base Flipping in Nucleotide Excision Repair [PDF]

Journal of Biological Chemistry, 2006
UvrB, the ultimate damage-binding protein in bacterial nucleotide excision repair is capable of binding a vast array of structurally unrelated lesions. A beta-hairpin structure in the protein plays an important role in damage-specific binding. In this paper we have monitored DNA conformational alterations in the UvrB-DNA complex, using the fluorescent ...
Malta, E., Moolenaar, G.F., Goosen, N.
openaire   +3 more sources

High-throughput analysis of DNA repair in microplates towards identification of inhibitors

Genes and Environment, 2020
Environmental factors can inhibit DNA repair and cause indirect mutagenic actions. Here the author introduces a recent paper on a novel high-throughput system to analyze the various enzymatic activities involved in base excision repair. Such systems will
Hiroyuki Kamiya
doaj   +1 more source

DNA Base Excision Repair Intermediates Influence Duplex–Quadruplex Equilibrium

Molecules, 2023
Although genomic DNA is predominantly duplex under physiological conditions, particular sequence motifs can favor the formation of alternative secondary structures, including the G-quadruplex.
Mark L. Sowers, James W. Conrad, Bruce Chang-Gu, Ellie Cherryhomes, Linda C. Hackfeld, Lawrence C. Sowers   +5 more
doaj   +1 more source

Viruses with U-DNA: New Avenues for Biotechnology

Viruses, 2021
Deoxyuridine in DNA has recently been in the focus of research due to its intriguing roles in several physiological and pathophysiological situations. Although not an orthodox DNA base, uracil may appear in DNA via either cytosine deamination or thymine ...
Kinga K. Nagy, Mikael Skurnik, Beáta G. Vértessy   +2 more
doaj   +1 more source

DNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection [PDF]

, 2010
Mycobacteria, including most of all MTB (Mycobacterium tuberculosis), cause pathogenic infections in humans and, during the infectious process, are exposed to a range of environmental insults, including the host's immune response.
Adams, Afanasev, Alina E. Gorna, Aly, Arnold, Bacon, Banu, Bergval, Betts, Boshoff, Boshoff, Bostanabad, Burney, Capelli, Chan, Chan, Cheng, Cooper, Cubillos-Ruiz, Darwin, Darwin, Das, Davis, Dos Vultos, Dubnau, Durbach, Farnia, Fennelly, Filliol, Fleischmann, Flint, Fontan, Friedberg, Frischkorn, Fu, Fu, Gaynor, Gordhan, Graham, Grishko, Guthlein, Hampshire, Hazbon, Hughes, Jain, Jaroslaw Dziadek, Jiao, Kapur, Karakousis, Karakousis, Karunkaran, Katti, Kesavan, Kim, Ko, Ko, Korycka-Machala, Krokan, Kurthkoti, Kurthkoti, Lari, Lever, Loudon, MacMicking, Malshetty, Martinez, Mokrousov, Moller, Movahedzadeh, Mulder, Munoz-Elias, Muttucumaru, Nguyen, Niemann, Nikolayevskyy, Nouvel, O'sullivan, Olano, Peccia, Peccia, Pitcher, Rachman, Rachman, Rad, Ramaswamy, Richard P. Bowater, Riley, Saito, Sander, Sassetti, Sassetti, Saunders, Schnappinger, Schwab, Sherman, Sinha, Sinha, Smeulders, Springer, Srivastava, Stephanou, Talaat, Talaat, Tang, Tsai, Venkatesh, Vilcheze, Voskuil, Voskuil, Waddell, Wanner, Warner, Weikert, Wiid, Wiseman, World Health Organization, Zaczek, Zainuddin   +117 more
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DNA repair: Disorders [PDF]

, 2010
No description ...
Bose, Burg, Caldecott, Chu, Digweed, Fernandez-Capetillo, Fousteri, Fousteri, Friedberg, Gudmundsdottir, Hashimoto, Hoeijmakers, Jiricny, Kraemer, Lavin, Lehmann, Lieber, Ma, Masutani, McCulloch, Meindl, Moldovan, Moshous, Nance, Nouspikel, O'Driscoll, O'Driscoll, O'Driscoll, O'Driscoll, Rass, Stefanini, Stewart, Stracker, Taylor, Vaz, Wu, Zlatanou   +36 more
core   +1 more source

The DNA Repair Protein XRCC1 Functions in the Plant DNA Demethylation Pathway by Stimulating Cytosine Methylation (5-meC) Excision, Gap Tailoring, and DNA Ligation [PDF]

, 2013
Background: Active DNA demethylation in plants is initiated by 5-meC DNA glycosylases of the ROS1/DME family and continued through a base excision repair pathway.
Córdoba-Cañero, Dolores, Martínez-Macías, M.I., Rodríguez Ariza, Rafael, Roldán-Arjona, Teresa   +3 more
core   +1 more source

Base excision repair and the role of MUTYH

Hereditary Cancer in Clinical Practice, 2007
The correction of exogenous and endogenous environmental insult to DNA involves a series of DNA repair mechanisms that reduce the likelihood of mutation accumulation and hence an increased probability of tumour development.
Kairupan Carla, Scott Rodney J
doaj   +1 more source