Type I-E CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition. [PDF]
PLoS Genetics, 2013 Discriminating self and non-self is a universal requirement of immune systems. Adaptive immune systems in prokaryotes are centered around repetitive loci called CRISPRs (clustered regularly interspaced short palindromic repeat), into which invader DNA ...
Edze R Westra +6 more
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Hoogsteen base pairs proximal and distal to echinomycin binding sites on DNA [PDF]
, 1987 Forms of the DNA double helix containing non-Watson-Crick base-pairing have been discovered recently based on x-ray diffraction analysis of quinoxaline antibiotic-oligonucleotide complexes.
Dervan, Peter B., Mendel, David
core +2 more sources
Effect of Molecular Crowding on DNA Polymerase Reactions along Unnatural DNA Templates
Molecules, 2020 Unnatural nucleic acids are promising materials to expand genetic information beyond the natural bases. During replication, substrate nucleotide incorporation should be strictly controlled for optimal base pairing with template strand bases. Base-pairing
Shuntaro Takahashi +2 more
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Genome-wide double-stranded RNA sequencing reveals the functional significance of base-paired RNAs in Arabidopsis. [PDF]
PLoS Genetics, 2010 The functional structure of all biologically active molecules is dependent on intra- and inter-molecular interactions. This is especially evident for RNA molecules whose functionality, maturation, and regulation require formation of correct secondary ...
Qi Zheng +8 more
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The effect of RNA stiffness on the self-assembly of virus particles [PDF]
, 2017 Under many in vitro conditions, some small viruses spontaneously encapsidate a single stranded (ss) RNA into a protein shell called the capsid. While viral RNAs are found to be compact and highly branched because of long distance base-pairing between ...
Erdemci-Tandogan, Gonca +3 more
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Triplet Superconductors from the Viewpoint of Basic Elements for Quantum Computers [PDF]
, 2002 We discuss possibilities of utilizing superconductors with Cooper condensates in triplet pairing states (where the spin of condensate pairs is S=1) for practical realization of quantum computers.
Gulian, Armen M., Wood, Kent S.
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The 5-chlorouracil:7-deazaadenine base pair as an alternative to the dT:dA base pair [PDF]
Organic & Biomolecular Chemistry, 2017 The 5-Cl-dU:7-deaza-dA base pair can be a substitute for the dT:dA base pair in an enzymatic replication process of 2 kb DNA.
Mikhail Abramov +4 more
openaire +6 more sources
TurboFold: Iterative probabilistic estimation of secondary structures for multiple RNA sequences
BMC Bioinformatics, 2011 Background The prediction of secondary structure, i.e. the set of canonical base pairs between nucleotides, is a first step in developing an understanding of the function of an RNA sequence.
Sharma Gaurav +2 more
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Base Pairs to Populations [PDF]
Clinical Cancer Research, 2017 “There is much work to be done and many challenges exist in our mission to end the suffering that breast cancer brings.” So conclude Guest Editors Ann Partridge and Lisa Carey in their overview for this CCR Focus on breast cancer.
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Schiff base-mediated base pairing [PDF]
Nucleic Acids Symposium Series, 2005 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Chikara Dohno +2 more
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