Base-Pairing and Base-Stacking Contributions to Double-Stranded DNA Formation.
Journal of Physical Chemistry B, 2020 Double-stranded (ds)DNA formation and dissociation are of fundamental biological importance. The negative DNA charge influences the dsDNA stability. However, the base pairing and the stacking between neighboring bases are responsible for the sequence ...
M. Zacharias
semanticscholar +1 more source
Base Pairing and Functional Insights into N3-methylcytidine (m3C) in RNA
bioRxiv, 2020 N3-methylcytidine (m3C) is present in both eukaryotic tRNA and mRNA and plays critical roles in many biological processes. We report the synthesis of the m3C phosphoramidite building block and its containing RNA oligonucleotides.
S. Mao +5 more
semanticscholar +1 more source
Journal of the American Chemical Society, 2020 Allosteric regulation is gaining increasing attention as a basis for production of stimuli-responsive materials in many research areas including DNA nanotechnology.
Takahiro Nakama +3 more
semanticscholar +1 more source
Aromatic N versus aromatic F : bioisosterism discovered in RNA base pairing interactions leads to a novel class of universal base analogs [PDF]
, 2010 The thermodynamics of base pairing is of fundamental importance. Fluorinated base analogs are valuable tools for investigating pairing interactions. To understand the influence of direct base–base interactions in relation to the role of water, pairing ...
Alrun N. Koller +74 more
core +1 more source
Hoogsteen base pairs proximal and distal to echinomycin binding sites on DNA [PDF]
, 1987 Forms of the DNA double helix containing non-Watson-Crick base-pairing have been discovered recently based on x-ray diffraction analysis of quinoxaline antibiotic-oligonucleotide complexes.
Dervan, Peter B., Mendel, David
core +2 more sources
The effect of RNA stiffness on the self-assembly of virus particles [PDF]
, 2017 Under many in vitro conditions, some small viruses spontaneously encapsidate a single stranded (ss) RNA into a protein shell called the capsid. While viral RNAs are found to be compact and highly branched because of long distance base-pairing between ...
Erdemci-Tandogan, Gonca +3 more
core +3 more sources
Genome-wide double-stranded RNA sequencing reveals the functional significance of base-paired RNAs in Arabidopsis. [PDF]
PLoS Genetics, 2010 The functional structure of all biologically active molecules is dependent on intra- and inter-molecular interactions. This is especially evident for RNA molecules whose functionality, maturation, and regulation require formation of correct secondary ...
Qi Zheng +8 more
doaj +1 more source
TurboFold: Iterative probabilistic estimation of secondary structures for multiple RNA sequences
BMC Bioinformatics, 2011 Background The prediction of secondary structure, i.e. the set of canonical base pairs between nucleotides, is a first step in developing an understanding of the function of an RNA sequence.
Sharma Gaurav +2 more
doaj +1 more source
Triplet Superconductors from the Viewpoint of Basic Elements for Quantum Computers [PDF]
, 2002 We discuss possibilities of utilizing superconductors with Cooper condensates in triplet pairing states (where the spin of condensate pairs is S=1) for practical realization of quantum computers.
Gulian, Armen M., Wood, Kent S.
core +3 more sources
Identification of the base-pairing requirements for repression of hctA translation by the small RNA IhtA leads to the discovery of a new mRNA target in Chlamydia trachomatis. [PDF]
PLoS ONE, 2015 The non-coding small RNA, IhtA expressed by the obligate intracellular human pathogen Chlamydia trachomatis modulates the translation of HctA, a key protein involved in replicative to infectious cell type differentiation.
Nicole A Grieshaber +5 more
doaj +1 more source