Results 171 to 180 of about 282,340 (392)

Basic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes. [PDF]

, 1988
Ruth Halaban, Robert C. Langdon, Nicholas Birchall, Charles B. Cuono, Andrew Baird, Glynis Scott, Gisela Moellmann, Joseph McGuire   +7 more
openalex   +1 more source

Intramyocardial and intracoronary basic fibroblast growth factor in porcine hibernating myocardium: a comparative study

, 2004
ObjectiveTherapeutic angiogenesis is an alternative method of revascularization for end-stage coronary artery disease. We determined the effects of intramyocardial and intracoronary basic fibroblast growth factor 2 on myocardial blood flow and function ...
Smith, Monica L, Landolfo, Carolyn, Carolyn Landolfo, Diodato, Luis, Lowe, James E, Biswas, Shankha S, Patrick W Domkowski, Luis Diodato, G.Chad Hughes, Monica L Smith, James E Lowe, Kevin P Landolfo, Landolfo, Kevin P, Brian H Annex, Hughes, G.Chad, Domkowski, Patrick W, John E Scarborough, Annex, Brian H, Shankha S Biswas, Scarborough, John E   +19 more
core   +1 more source

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

Thromboxane A2 stimulates vascular smooth muscle hypertrophy by up-regulating the synthesis and release of endogenous basic fibroblast growth factor

, 1993
Safdar Ali, Michael G. Davis, Michael W. Becker, G W Dorn   +3 more
openalex   +1 more source

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

Advanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia, Chenfei Kong, Xiaoming Zhao, Naixu Shi, Jinlan Jiang, Ping Li   +5 more
wiley   +1 more source

Effect of recombinant bovine basic fibroblast growth factor gel on repair of rosacea skin lesions: A randomized, single‑blind and vehicle‑controlled study

, 2019
Yang Luo, Xiu‐Li Luan, Yujiao Sun, Li Zhang, Jian‐Hong Zhang   +4 more
openalex   +2 more sources

Mice expressing a bovine basic fibroblast growth factor transgene in the brain show increased resistance to hypoxemic-ischemic cerebral damage.

, 1993
Cerebral intraventricular infusion of acidic or basic fibroblast growth factor has been shown to attenuate ischemic damage to hippocampal CA1 neurons in the gerbil.
A Wiseman, D Settles, D Judge, J Davis, V MacMillan, J Swain   +5 more
core   +1 more source

DOT1L Drives Endothelial‐to‐Mesenchymal Transition and Fibrotic Vascular Remodeling via H3K79 Methylation

Advanced Science, EarlyView.
DOT1L as a central epigenetic regulator of EndoMT and pulmonary fibrosis. Acting as an early epigenetic switch, it translates TGFβ–SMAD signaling into H3K79me2‐mediated chromatin remodeling, selectively activates fibrosis‐related genes, and primes ECs for rapid mesenchymal transition.
Yaofeng Wang, Xing Peng, Jingjing Chen, Yun Zhang, Tinghong Zhang, Jingyuan Zhang, Jiaying Fan, Hui Zheng, Qiaoyuan Liu, Zhimin Song, Zhan‐Peng Huang, Shu Meng   +11 more
wiley   +1 more source

Basic Fibroblast Growth Factor (bFGF) Incorporating Gelatin Hydrogel Accelerates Wound Healing in Refractory Ulcers in the 2 Dogs

, 2011
Keisuke Kudo, Masaaki Miyamoto, Yasuhiko Tabata, Masahiro TAGAWA   +3 more
openalex   +2 more sources

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source