Results 1 to 10 of about 113,312 (290)

Basophil-derived exosomes exacerbate systemic lupus erythematosus by regulating B-cell proliferation via miR-24550 [PDF]

BMC Medicine
Background Systemic lupus erythematosus (SLE) is a complex autoimmune disease where B-cell proliferation and activation play a pivotal role in pathogenesis.
Jiaxuan Chen, Shuzhen Liao, Jiaqi Lun, Xing Lu, Bitang Huang, Xiaoxian Liu, Xiaowei Xu, Lawei Yang, Fengbiao Guo, Liuyong You, Haiyan Xiao, Hua-Feng Liu, Qingjun Pan   +12 more
doaj   +2 more sources

What Basophil Testing Tells Us About CSU Patients – Results of the CORSA Study

Frontiers in Immunology, 2021
Basophil testing is the most effective single approach for diagnosing type-IIb autoimmune chronic spontaneous urticaria (TIIbaiCSU). A positive basophil test has been linked to long disease duration, higher disease activity, a poor response to ...
João Marcelino, Katrine Baumann, Katrine Baumann, Katrine Baumann, Per Stahl Skov, Per Stahl Skov, Maria Conceição Pereira Santos, Inga Wyroslak, Jörg Scheffel, Jörg Scheffel, Sabine Altrichter, Sabine Altrichter, Anders Woetmann, Anders Woetmann, Manuel Pereira-Barbosa, Célia Costa, Marcus Maurer, Marcus Maurer   +17 more
doaj   +1 more source

Immunological Changes of Basophil Hyperreactivity to Sweat in Patients With Well-Controlled Atopic Dermatitis

Frontiers in Immunology, 2022
BackgroundSweat aggravates atopic dermatitis (AD). In patients with AD, type-I hypersensitivity to sweat may be shown by histamine release from patients’ basophils in response to the semi-purified sweat antigen (QR), and the presence of specific ...
Tomofumi Numata, Shunsuke Takahagi, Kaori Ishii, Satoshi Morioke, Takanobu Kan, Hayato Mizuno, Yuhki Yanase, Tomoko Kawaguchi, Akio Tanaka, Michihiro Hide   +9 more
doaj   +1 more source

Basophils from allergy to cancer

Frontiers in Immunology, 2022
Human basophils, first identified over 140 years ago, account for just 0.5-1% of circulating leukocytes. While this scarcity long hampered basophil studies, innovations during the past 30 years, beginning with their isolation and more recently in the ...
Remo Poto, Remo Poto, Remo Poto, Adriana Rosa Gambardella, Adriana Rosa Gambardella, Gianni Marone, Gianni Marone, Gianni Marone, Gianni Marone, John T. Schroeder, Fabrizio Mattei, Giovanna Schiavoni, Gilda Varricchi, Gilda Varricchi, Gilda Varricchi, Gilda Varricchi   +15 more
doaj   +1 more source

Findings of in vitro Analyses of Basophil Functions May Help Us Better Understand Drug Desensitization

Frontiers in Allergy, 2022
Drug hypersensitivity can be an important problem during pharmacological management of various diseases. Patients diagnosed as having a drug allergy usually need to avoid the offending drug, either temporarily or for life.
Masao Yamaguchi, Akiko Komiya, Maho Suzukawa, Rikiya Koketsu, Risa Shiragami, Motoyasu Iikura, Hiroyuki Nagase   +6 more
doaj   +1 more source

Basophil Production [PDF]

Journal of Clinical Investigation, 1980
Factors influencing basophil production from the bone marrow of ovalbumin (OA)-sensitized guinea pigs have been examined in vitro. Autologous co-cultures of marrow and spleen cells from OA-immune animals contained significantly higher numbers of basophils after 7 d of liquid culture in the presence of OA, compared with control co-cultures or with ...
J A, Denburg, M, Davison, J, Bienenstock
openaire   +2 more sources

Eosinophils Are More Strongly Relevant to Allergic Sensitization Than Basophils in Pediatric Adenotonsillar Hypertrophy

Frontiers in Pediatrics, 2021
The relationship between eosinophils/basophils and allergic sensitization is not clear in pediatric adenotonsillar hypertrophy (ATH). The objective of this study is to investigate the relationship between eosinophil/basophil counts and peripheral ...
Juanjuan Zou, Yan Yang, Qiang Fu, Huayang Liu, Chao Zhang, Lili Liu, Yan Wang, Yanzhong Li   +7 more
doaj   +1 more source

Exposure of the Basophilic Cell Line KU812 to Liposomes Reveals Activation Profiles Associated with Potential Anaphylactic Responses Linked to Physico-Chemical Characteristics

Pharmaceutics, 2022
Lipidic nanoparticles (LNP), particularly liposomes, have been proven to be a successful and versatile platform for intracellular drug delivery for decades.
Alexander J. Plant-Hately, Burcu Eryilmaz, Christopher A. W. David, Danielle E. Brain, Bethany J. Heaton, Yvonne Perrie, Neill J. Liptrott   +6 more
doaj   +1 more source

Basophil Count, Percentage of Basophil and Basophil Lymphocyte Ratio in Psychiatry Practice: Current Approaches and Future Directions

Journal of Contemporary Medicine, 2020
It is an easy and inexpensive method to utilize hematologic parameters in cases where we cannot get clear information from the patients. The basophils are definitely involved in immunopathologic responses to parasites, and in this respect, there may be a
Mehmet Hamdi Orum
doaj   +1 more source

Plasmacytoid dendritic cells diminution in peripheral blood is prevalent in drug reaction with eosinophilia and systemic symptoms and may precede human herpesvirus 6 reactivation

Dermatologica Sinica, 2021
Background: Plasmacytoid dendritic cells (pDCs) are implicated in the reactivation of human herpesvirus 6 (HHV-6) in drug reaction with eosinophilia and systemic symptoms (DRESS).
Shao-Hsuan Hsu, Che-Wen Yang, Yi-Chun Hsieh, Kai-Lung Chen, Yung-Tsu Cho, Jau-Yu Liau, Chia-Yu Chu   +6 more
doaj   +1 more source