Results 81 to 90 of about 113,312 (290)
Immunobiology of Acquired Resistance to Ticks
Frontiers in Immunology, 2020 Ticks are blood-sucking arthropods of great importance in the medical and veterinary fields worldwide. They are considered second only to mosquitos as vectors of pathogenic microorganisms that can cause serious infectious disorders, such as Lyme ...
Hajime Karasuyama +2 more
doaj +1 more source
Age-dependent sensitization to the 7S-vicilin-like protein Cor a 11 from hazelnut (Corylus avellana) in a birch-endemic region [PDF]
, 2012 Background: Hazelnut (Corylus avellana) allergy exhibits age and geographically distinct sensitization patterns that have not yet been fully resolved. Objective: To study sensitization to Cor a 11 in different age groups of hazelnut-allergic patients and
Bridts, CH +8 more
core +1 more source
Navigating adverse immunostimulation: A practical guide for clinical researchers
British Journal of Clinical Pharmacology, EarlyView.Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort +3 more
wiley +1 more source
When is a mouse basophil not a basophil?
Blood, 2006 AbstractThe identification and characterization of mouse basophils have historically been hampered by the extreme rarity of this cell type. Virtually no photomicrographs of hematologically stained (eg, Wright-Giemsa) examples of mouse basophils exist in the literature. However, 4 recent studies in the past 2 years have used flow cytometry and a defined
James J, Lee, Michael P, McGarry
openaire +3 more sources
気管支喘息患者における細胞性免疫,ガンジダ抗原に対する遅延型反応の抑制 [PDF]
, 1992 Delayed cutaneous hypersensitivity towards Candida albicans was examined in 200 patients with bronchial asthma in relation to patient age and the level of total IgE. 1.
Harada, Hideo +7 more
core +1 more source
Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases
BMEMat, EarlyView.This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou +6 more
wiley +1 more source
SLAP Is a Negative Regulator of FcεRI Receptor-Mediated Signaling and Allergic Response
Frontiers in Immunology, 2019 Binding of antigen to IgE-high affinity FcεRI complexes on mast cells and basophils results in the release of preformed mediators such as histamine and de novo synthesis of cytokines causing allergic reactions.
Namit Sharma +12 more
doaj +1 more source
Cytometry Part B: Clinical Cytometry, EarlyView.Abstract Basophils are effector cells in type I hypersensitivity reactions. Upon cross‐linking of surface‐bound (allergen‐specific) IgE, basophils release a variety of mediators. Determining the activation of basophils ex vivo with anti‐IgE (a basophil activation test or BAT) can be achieved using flow cytometry.
T. C. Pelgrim +7 more
wiley +1 more source
IgE Autoreactivity in Atopic Dermatitis: Paving the Road for Autoimmune Diseases?
Antibodies, 2020 Atopic dermatitis (AD) is a common skin disease affecting 20% of the population beginning usually before one year of age. It is associated with the emergence of allergen-specific IgE, but also with autoreactive IgE, whose function remain elusive.
Christophe Pellefigues
doaj +1 more source
, 1992 Skin tests, serum total IgE levels, specific IgE antibodies against each allergen, bronchial reactions provoked by allergens and histamine release from basophils are well known as prameters of immediate allergic reactions.
Kitani, Hikaru +4 more
core +1 more source