Results 71 to 80 of about 159,800 (296)

Blood-brain barrier breach after acute cerebral hypoxia in infants

Реабилитология
Background. Neuronal lesion, including hypoxic-ischemic damage to the central nervous system (CNS) in perinatal period, leads to the release of neuron-specific enolase (NSE) into peripheral bloodstream. Consequently, NSE can be considered as a biological
A. G. Aleksandrov, D. V. Blinov
doaj   +1 more source

Counting subgroups of the groups ${\Bbb Z}_{n_1} \times \cdots \times {\Bbb Z}_{n_k}$: a survey [PDF]

We present a survey of exact and asymptotic formulas on the number of cyclic subgroups and total number of subgroups of the groups ${\Bbb Z}_{n_1} \times \cdots \times {\Bbb Z}_{n_k}$, where $k\ge 2$ and $n_1,\ldots,n_k$ are arbitrary positive integers ...
Tóth, László
core   +1 more source

Logistic Regression predictions for TDC BBB-Martins Leaderboard

, 2023
Logistic Regression predictions for a drugs ability to penetrate the blood brain barrier using Therapeutic Data Commons BBB-Martins dataset. Includes .tsv files with the actual and predicted classifications of BBB permeability for each drug in the TDC ...
Rick Fontenot (14855842)
core   +1 more source

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

Advanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang, Hongyu Zhu, Wenqi Wang, Bingqian Shen, Yuanyuan Xin, Xingxing Song, Xuanyi Lu, Lixuan Li, Siting Chen, Xiaochen Zhang, Jialing Zeng, Haodong Zheng, Jianlong Lao, Ke Peng, Yixian Wei, Jiaming Zheng, Chuanhuo Hu, Xiaoye Wang, Xun Li   +18 more
wiley   +1 more source

СURRENT CONCEPTS OF THE ROLE OF ALTERED BLOOD-BRAIN BARRIER RESISTANCE IN THE PATHOGENESIS OF CNS DISORDERS. PART II: FUNCTIONS AND MECHANISMS OF THE BLOOD-BRAIN BARRIER DAMAGE

Эпилепсия и пароксизмальные состояния, 2016
: altered permeability of the blood-brain  barrier (BBB) plays a key role in the pathogenesis of epilepsy as well as vascular, demyelinating, neurodegenerative central neural system (CNS) diseases, head injury, hypoxic-ischemic CNS damage in obstetric ...
D. V. Blinov
doaj  

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

On weighted spaces of functions harmonic in $\Bbb R^n$

, 2006
summary:The paper establishes integral representation formulas in arbitrarily wide Banach spaces $b^p_\omega(\Bbb R^n)$ of functions harmonic in the whole $\Bbb R^n$
Petrosyan, A. I.
core   +1 more source

Innovations in Breaking Barriers: Liposomes as Near-Perfect Drug Carriers in Ischemic Stroke Therapy

International Journal of Nanomedicine
Qiankun Zhang,* Songze Huang,* Xiaowen Liu, Wei Wang, Zhihan Zhu, Lukui Chen Department of Neurosurgery, Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine, Southern Medical University, Guangzhou, Guangdong ...
Zhang Q, Huang S, Liu X, Wang W, Zhu Z, Chen L   +5 more
doaj  

PATIENTS WITH NEUROLOGICAL DISEASES: RATIONALE FOR PHARMACOECONOMIC EVALUATION OF COST OPTIMIZATION FOR MANAGEMENT WITH NEURON-SPECIFIC PROTEINS ASSESSMENT AS MARKERS OF INCREASED BLOOD-BRAIN-BARRIER PERMEABILITY

Фармакоэкономика, 2015
becoming increasingly widespread evaluation of the blood-brain barrier (BBB) resistance to predict severity and outcome of epilepsy, stroke, traumatic brain injury (TBI) and other neurological disorders by assessment of neuron-specific proteins (NSP ...
D. V. Blinov
doaj  

Deep Neural Network predictions for TDC BBB-Martins Leaderboard

, 2023
Deep Neural Network predictions for a drugs ability to penetrate the blood brain barrier using Therapeutic Data Commons BBB-Martins dataset. Includes .tsv files with the actual and predicted classifications of BBB permeability for each drug in the TDC ...
Rick Fontenot (14855842)
core   +1 more source