Results 211 to 220 of about 159,800 (296)

Role of the Blood-Brain Barrier in the Pathophysiology of Major Depressive Disorder, Bipolar Disorder, and Schizophrenia: A Comparative Review. [PDF]

Pharmaceuticals (Basel)
Rostevanov IS, Damri O, Azab AN, Agam G.
europepmc   +1 more source

Pharmacogenetics Governance for Youth Mental Health: A Scoping Review of Policy Across 13 Countries

Clinical Pharmacology &Therapeutics, EarlyView.
Pharmacogenetics (PGx) testing could improve psychotropic prescribing for children and young people, yet youth‐specific policy guidance remains scarce. This review characterizes the international PGx policy landscape for youth mental health across 13 countries.
Prosper Mandela Amaltinga Awuni, Bishnu B. Bajgain, Diane L. Lorenzetti, Gina Dimitropoulos, Paul D. Arnold, Jennifer Zwicker, Chad Bousman   +6 more
wiley   +1 more source

Streptococcus suis-induced mitophagy via Eno-HSP90AA1 interaction disrupts the blood-brain barrier. [PDF]

Vet Res
Xiao X, Zhou Y, Fang Y, van der Veen S, Lin XA, Lou Y, Gao S.   +6 more
europepmc   +1 more source

Quantitative Insights into Atomic Scale Oil–Clay Adhesion Governing Shale Oil Retention and Mobility

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Atomic force microscopy reveals a clear adhesion hierarchy between shale oil and clay minerals, governed by nanoscale surface chemistry. Strong interactions on chlorite and illite arise from abundant polar sites and cation bridging, whereas weaker coupling on montmorillonite limits interfacial binding.
Chen Lv, Guanwen Lu, Guandong Su
wiley   +1 more source

Changes in Core Temperature Following Administration of FC5, a Blood-Brain Carrier Fused with Neurotensin in Mice, Rats and Non-Human Primates. [PDF]

Cells
Yogi A, Lessard E, Brunette E, Delaney CE, Haqqani AS, Robotham A, Alata W, Moreno MJ, Stanimirovic DB.   +8 more
europepmc   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

Adeno‐associated virus‐mediated restoration of NaV1.1 in targeted brain regions ameliorates epilepsy in symptomatic Dravet syndrome mice

Epilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a developmental and epileptic encephalopathy primarily caused by haploinsufficiency of the SCN1A gene, which encodes the alpha subunit of NaV1.1 voltage‐gated sodium channel. The disease manifests with febrile and spontaneous seizures, developmental delay, cognitive impairment, and increased risk of sudden ...
Martina Mainardi, Simone Brusco, Serena Gea Giannelli, Vania Broccoli, Gaia Colasante   +4 more
wiley   +1 more source

The A-FABP Nexus in the Neurovascular Unit: Bridging Endothelial Barrier Breakdown and Microglial Lipotoxicity in Ischemic Stroke. [PDF]

J Inflamm Res
Ma WY, Yao L, Lan W.
europepmc   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source