Results 21 to 30 of about 18,005 (233)

Association of BCAAs/BCKAs with pancreatic steatosis in patients with type 2 diabetes mellitus: A cross-sectional study. [PDF]

J Diabetes Investig
ABSTRACT Aims To examine the association between branched‐chain α‐keto acids (BCKAs) and pancreatic steatosis in patients with type 2 diabetes (T2DM). Methods This cross‐sectional study was conducted from January 2023 to March 2025. Upper abdominal computerized tomography was performed, pancreatic volume (PV), PV index (PVI), CT attenuation of pancreas
Gao J, Cheng P, Jiang F, Li W, Shi Y, Wang W, Wang L, Lei T, Zang Y, Lu J.   +9 more
europepmc   +2 more sources

Adipose Tissue Branched Chain Amino Acid (BCAA) Metabolism Modulates Circulating BCAA Levels [PDF]

Journal of Biological Chemistry, 2010
Whereas the role of adipose tissue in glucose and lipid homeostasis is widely recognized, its role in systemic protein and amino acid metabolism is less well-appreciated. In vitro and ex vivo experiments suggest that adipose tissue can metabolize substantial amounts of branched chain amino acids (BCAAs).
Mark A, Herman, Pengxiang, She, Odile D, Peroni, Christopher J, Lynch, Barbara B, Kahn   +4 more
openaire   +2 more sources

The KRAS-BCAA-BCAT2 axis in PDAC development [PDF]

Nature Cell Biology, 2020
Understanding the metabolic rewiring of pancreatic ductal adenocarcinoma is an emerging strategy for identifying cancer-associated liabilities and improving treatment. A new study now elucidates the function of the transaminase BCAT2 in the early stages of tumor development, providing insights that could stimulate novel therapeutic strategies.
Falcone, Mattia, Maddocks, Oliver D.K.
openaire   +2 more sources

Omega-3 fatty acids enhance the beneficial effect of BCAA supplementation on muscle function following eccentric contractions

Journal of the International Society of Sports Nutrition, 2022
Background This study investigated the combined effect of branched-chain amino acids (BCAA) and fish oil (FO) on muscle damage caused by eccentric contractions (ECCs) of the elbow flexors, with a special focus on muscular function.
Yosuke Tsuchiya, Kenichi Yanagimoto, Norihiko Sunagawa, Hisashi Ueda, Katsunori Tsuji, Eisuke Ochi   +5 more
doaj   +1 more source

BCAA manuscript Table S3

, 2022
Enrichment in β-hydroxybutyrate isotopomers, determined following 5 and 10 minutes of incubation of the liver mitochondria in a respiration buffer containing 20µM [13C16]palmitate, following BCAA supplemetation to mice. 
Vaishna Muralidaran (12438189), David Zhao (14070269), Nishanth Sunny (14124747), Kruti Patel (5484875), Chaitra Surugihalli (2627731), Caitlin E. Ryan (14134648)   +5 more
core   +1 more source

Bioregional Alterations in Gut Microbiome Contribute to the Plasma Metabolomic Changes in Pigs Fed with Inulin

Microorganisms, 2020
Inulin (INU) is a non-digestible carbohydrate, known for its beneficial properties in metabolic disorders. However, whether and how gut microbiota in its regulation contributes to host metabolism has yet to be investigated.
Weida Wu, Li Zhang, Bing Xia, Shanlong Tang, Lei Liu, Jingjing Xie, Hongfu Zhang   +6 more
doaj   +1 more source

Rates of liver related decompensations according to quartiles of BCAA intake derived from average daily BCAA intake (measured in grams of BCAA per 1000 kcal of daily energy intake).

, 2023
Rates of liver related decompensations according to quartiles of BCAA intake derived from average daily BCAA intake (measured in grams of BCAA per 1000 kcal of daily energy intake).
Lei Yu (70258), Jennifer Dodge (15353996), Kiran Bambha (15353999), Scott W. Biggins (15354002), Shirley C. Paski (15353993), George N. Ioannou (8792069)   +5 more
core   +1 more source

Crude and adjusted hazard ratios of liver-related death or transplantation according to quartiles of BCAA intake derived from average daily energy adjusted BCAA intake (measured in grams of BCAA per 1000 kcal of daily energy intake).

, 2023
Crude and adjusted hazard ratios of liver-related death or transplantation according to quartiles of BCAA intake derived from average daily energy adjusted BCAA intake (measured in grams of BCAA per 1000 kcal of daily energy intake).
Lei Yu (70258), Jennifer Dodge (15353996), Kiran Bambha (15353999), Scott W. Biggins (15354002), Shirley C. Paski (15353993), George N. Ioannou (8792069)   +5 more
core   +1 more source

Action of leucine in heart hypertrophy induced by thyroid hormone in rats

Bioscience Journal, 2016
Leucine is a regulator of protein metabolism in vivo, but there is little information regarding its effect on hyperthyroidism-induced cardiac hypertrophy.
Thiago Montes Fidale, Alexandre Gonçalves, Eduardo Gaspareto Haddad, Fernanda Rodrigues de Souza, Beatriz Montes Fidale, Fernando Cézar Veloso, Elmiro Santos Resende   +6 more
doaj   +1 more source

Role of branched-chain amino acid metabolism in the pathogenesis of obesity and type 2 diabetes-related metabolic disturbances BCAA metabolism in type 2 diabetes

Nutrition & Diabetes, 2022
Branched-chain amino acid (BCAA) catabolism has been considered to have an emerging role in the pathogenesis of metabolic disturbances in obesity and type 2 diabetes (T2D).
Froukje Vanweert, Patrick Schrauwen, Esther Phielix   +2 more
doaj   +1 more source