Results 171 to 180 of about 59,389 (246)

First in human phase 1 study of DT2216, a selective BCL-xL degrader, in patients with relapsed/refractory solid malignancies. [PDF]

J Hematol Oncol
Mahadevan D, Barve M, Mahalingam D, Parekh J, Kurman M, Strauss J, Tremaine L, Hromas R, Sills J, McCulloch J, Harkey J, Suberg S, Zimmerman L, Zheng G, Zhou D.   +14 more
europepmc   +1 more source

Quiescent OXPHOS-High Triple-Negative Breast Cancer Cells That Persist After Chemotherapy Depend on BCL-XL for Survival. [PDF]

Cells
Andrzejewski S, Winter M, Encarnacao Garcia L, Akinrinmade O, Madeira Marques F, Zacharioudakis E, Skwarska A, Aguirre-Ghiso J, Konopleva M, Zheng G, Fineberg SA, Zhou D, Gavathiotis E, Wang T, Dhimolea E.   +14 more
europepmc   +1 more source

Tanshinone IIA inhibits human gastric carcinoma AGS cell growth by decreasing BiP, TCTP, Mcl-1 and Bcl-xL and increasing Bax and CHOP protein expression

, 2014
CHIN-CHENG SU
openalex   +2 more sources

Synergy between phosphatidylinositol 3-kinase/Akt pathway and Bcl-xL in the control of apoptosis in adenocarcinoma cells of the lung [PDF]

, 2009
Jun Qian, Yong Zou, Jamshedur Rahman, Jiahong Lu, Pierre P. Massion   +4 more
openalex   +1 more source

Direct Co-Targeting of Bcl-xL and Mcl-1 Exhibits Synergistic Effects in AR-V7-Expressing CRPC Models. [PDF]

Cancer Res Commun
Brim BC, Leon AF, Beatson EL, Kindrick JD, Bhadresha K, Zhang X, Napoli GC, Risdon EN, Schmidt KT, Wilson KM, McKnight C, Beck E, Klumpp-Thomas C, Ceribelli M, Yin J, Sowalsky AG, Price DK, Chau CH, Thomas CJ, Figg WD.   +19 more
europepmc   +1 more source

BCL-xL Receptor.pdb.id & chemical structure (1YSG) Structure, ID code and origin or source of protein with the shared amino acids.

Randa Mohammed Zaki (21637175), Basmah Nasser Aldosari (21637178), Layla A. Alkharashi (21637181), Alyaa Alsalhi (21637184), Obaid Afzal (10509562), Bodoor Ghanem Alanazi (21637187), Maha Alsunbul (19562044), Rawan Bafail (21637190), Fatma I. Abo El-Ela (17303624), Hanan O. Farouk (21637193)   +9 more
openalex   +1 more source

Exploration of Multiconformers to Extract Information About Structural Deformation Undergone by a Protein Target: Illustration on the Bcl-xL Target. [PDF]

Molecules
Baillif M, Tempez E, Badel A, Regad L.
europepmc   +1 more source

BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation-Induced Apoptosis. [PDF]

Clin Cancer Res
Panda PK, Paschoalini Mafra AC, Bastos ACS, Cao L, Serra Bonet M, Brashears CB, Chen EY, Benedict-Hamilton HM, Ehrhardt W, Bomalaski J, Dehner C, Rogers LC, Oyama T, Van Tine BA.   +13 more
europepmc   +1 more source

The dual BCL-2 and BCL-XL inhibitor AZD4320 acts on-target and synergizes with MCL-1 inhibition in B-cell precursor ALL

Maren Christiane Wichert, Colin Fortner, Alexandra Niedermayer, Johanna Bender, Stefanie Enzenmüller, Klaus‐Michael Debatin, Lüder Hinrich Meyer, Felix Seyfried   +7 more
openalex   +1 more source

Molecular mechanisms underlying HRK interaction with BCL-XL and BCL-2 reveal specificity determinants for BH3 mimetics. [PDF]

iScience
Wang J, Guo M, Dai S, Wei H.
europepmc   +1 more source