Results 11 to 20 of about 35,489 (280)

Upward trend in follicular lymphoma among the Korean population: 10-year experience at a large tertiary institution [PDF]

open access: yesJournal of Pathology and Translational Medicine, 2021
Background Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL) in Western countries. However, it is relatively rare in Asia.
Meejeong Kim   +7 more
doaj   +1 more source

High-Grade B-Cell Lymphoma (HGBL) with MYC and BCL2 and/or BCL6 Rearrangements Is Predominantly BCL6-Rearranged and BCL6-Expressing in Taiwan [PDF]

open access: yesCancers, 2021
This study investigated the epidemiological and clinical peculiarities of BCL2 and BCL6 rearrangement in patients with high grade B-cell lymphoma (HGBL) from Taiwan, compared with data from Western countries. Two hundred and eighty-two DLBCL cases from Taipei Medical University-affiliated hospitals (n = 179) and Tri-Service General Hospital (n = 103 ...
Cheng-Chih Tsai   +23 more
openaire   +2 more sources

Prevention of Cholestatic Liver Disease Through BCL6-FXR Enterohepatic Crosstalk. [PDF]

open access: goldCell Mol Gastroenterol Hepatol
Fruzyna E   +7 more
europepmc   +2 more sources

Deficiency of the transcriptional repressor B cell lymphoma 6 (Bcl6) is accompanied by dysregulated lipid metabolism. [PDF]

open access: yesPLoS ONE, 2014
The transcriptional repressor B-cell Lymphoma 6 (Bcl6) was recently identified in a profile of genes regulated in adipocytes, suggesting a relationship between Bcl6 and metabolic regulation.
Christopher R LaPensee   +3 more
doaj   +1 more source

High Ki67 proliferation index but not cell-of-origin subtypes is associated with shorter overall survival in diffuse large B-cell lymphoma

open access: yesAvicenna Journal of Medicine, 2020
Background: CD10, BCL6, and MUM1 are commonly used immunohistochemical stains for classifying diffuse large B-cell lymphoma (DLBCL), which is useful in predicting outcome.
Feras Zaiem   +6 more
doaj   +1 more source

An Expanding Job Description for Bcl6 [PDF]

open access: yesJournal of Molecular Cell Biology, 2009
B cell lymphoma/leukemia gene 6 (Bcl6) is well known as a master regulator of germinal center (GC) B cell differentiation. Now, three new publications demonstrate that Bcl6 also plays a second role in GC response, in that it is both required and sufficient to drive the differentiation of T follicular helper cells.
Enguang, Bi, B Hilda, Ye
openaire   +2 more sources

B-cell lymphoma 6 alleviates nonalcoholic fatty liver disease in mice through suppression of fatty acid transporter CD36

open access: yesCell Death and Disease, 2022
Nonalcoholic fatty liver disease (NAFLD) is an ubiquitous disease that exists across a wide spectrum ranging from steatosis, steatohepatitis, advanced fibrosis, and liver cirrhosis.
Hao Zhang   +13 more
doaj   +1 more source

Alternative splicing generates a short BCL6 (BCL6S) isoform encoding a compact repressor [PDF]

open access: yesBiochemical and Biophysical Research Communications, 2008
BCL6 gene transcribes two main mRNA isoforms, variant 1 and variant 2, which have distinct transcription start sites. However, these two isoforms encode identical BCL6 protein. Recently, a third variant was sequenced from a human hippocampus cDNA library (DB465062). In this study, we cloned and sequenced a novel BCL6 spliced isoform (BCL6S) which lacks
Yulei, Shen   +4 more
openaire   +2 more sources

Convergent BCL6 and lncRNA promoters demarcate the major breakpoint region for BCL6 translocations [PDF]

open access: yesBlood, 2015
To the editor: We recently published a study showing that BCL6 translocations occur at distinct sequence motifs within intron 1 of the BCL6 gene that are recognized and deaminated by activation-induced cytidine deaminase (AID).[1][1] It has been unclear, however, why these breakpoints cluster in ...
Zhengfei, Lu   +5 more
openaire   +2 more sources

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