Results 21 to 30 of about 22,830 (227)

The role of Bcl6 in mature cardiac myocytes [PDF]

Cardiovascular Research, 1999
The Bcl6 gene encodes a sequence-specific transcriptional repressor and is ubiquitously expressed in adult murine tissues including heart muscle. The objective of this study was to examine the role of Bcl6 in cardiac myocytes.We developed Bcl6-deficient (Bcl6-/-) mice and histologically examined hearts from these mice.Massive myocarditis with ...
Haruhiko Koseki, Kazuki Ishibashi, Masafumi Arima   +2 more
exaly   +3 more sources

t(3;3)(q27;q27) ST6GAL1/BCL6 - del(3)(q27q27) ST6GAL1/BCL6 [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2012
Review on t(3;3)(q27;q27) ST6GAL1/BCL6 - del(3)(q27q27) ST6GAL1/BCL6, with data on clinics, and the genes involved.
Huret, JL
openaire   +4 more sources

BCL6 inhibition: a promising approach to prevent germinal center-driven allo-immune responses. [PDF]

Front Immunol
After solid organ transplantation, antibody-mediated rejection (AMR) is the most important cause of late allograft loss. Central in this process are donor-specific antibodies (DSAs) targeting mismatched Human Leukocyte Antigens (HLA) on recipient endothelial cells.
Kraaijeveld R, Hesselink DA, Steines L, Heidt S, Baan CC.   +4 more
europepmc   +2 more sources

Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6 [PDF]

Cell Reports, 2017
The transcription factor BCL6 is a known driver of oncogenesis in lymphoid malignancies, including diffuse large B cell lymphoma (DLBCL). Disruption of its interaction with transcriptional repressors interferes with the oncogenic effects of BCL6. We used
Nina Kerres, Steffen Steurer, Stefanie Schlager, Gerd Bader, Helmut Berger, Maureen Caligiuri, Christian Dank, John R. Engen, Peter Ettmayer, Bernhard Fischerauer, Gerlinde Flotzinger, Daniel Gerlach, Thomas Gerstberger, Teresa Gmaschitz, Peter Greb, Bingsong Han, Elizabeth Heyes, Roxana E. Iacob, Dirk Kessler, Heike Kölle, Lyne Lamarre, David R. Lancia, Simon Lucas, Moriz Mayer, Katharina Mayr, Nikolai Mischerikow, Katja Mück, Christoph Peinsipp, Oliver Petermann, Ulrich Reiser, Dorothea Rudolph, Klaus Rumpel, Carina Salomon, Dirk Scharn, Renate Schnitzer, Andreas Schrenk, Norbert Schweifer, Diane Thompson, Elisabeth Traxler, Roland Varecka, Tilman Voss, Alexander Weiss-Puxbaum, Sandra Winkler, Xiaozhang Zheng, Andreas Zoephel, Norbert Kraut, Darryl McConnell, Mark Pearson, Manfred Koegl   +48 more
doaj   +2 more sources

Loss of Bcl6 promotes antitumor immunity by activating glycolysis to rescue CD8 T-cell function [PDF]

Life Science Alliance
BCL6 limits CD8 T-cell responses to tumors by inhibiting Glut3 expression. Conditional deletion of Bcl6 in activated CD8 T cells or pharmacological inhibition of BCL6 in mice represses tumor growth.
Fangkun Luan, Yunqiao Li, Jia Ning, Jenny Tuyet Tran, Tanya R Blane, Raag Bhargava, Zhe Huang, Changchun Xiao, David Nemazee   +8 more
doaj   +2 more sources

Upward trend in follicular lymphoma among the Korean population: 10-year experience at a large tertiary institution [PDF]

Journal of Pathology and Translational Medicine, 2021
Background Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL) in Western countries. However, it is relatively rare in Asia.
Meejeong Kim, Hee Sang Hwang, Hyungwoo Cho, Dok Hyun Yoon, Cheolwon Suh, Chan Sik Park, Heounjeong Go, Jooryung Huh   +7 more
doaj   +1 more source

BCL6 IGH rearrangement FISH [PDF]

, 2023
BCL6 IGH rearrangement FISH images and cases ...
Carreras, Joaquim
core   +1 more source

Deficiency of the transcriptional repressor B cell lymphoma 6 (Bcl6) is accompanied by dysregulated lipid metabolism. [PDF]

PLoS ONE, 2014
The transcriptional repressor B-cell Lymphoma 6 (Bcl6) was recently identified in a profile of genes regulated in adipocytes, suggesting a relationship between Bcl6 and metabolic regulation.
Christopher R LaPensee, Grace Lin, Alexander L Dent, Jessica Schwartz   +3 more
doaj   +1 more source

High Ki67 proliferation index but not cell-of-origin subtypes is associated with shorter overall survival in diffuse large B-cell lymphoma

Avicenna Journal of Medicine, 2020
Background: CD10, BCL6, and MUM1 are commonly used immunohistochemical stains for classifying diffuse large B-cell lymphoma (DLBCL), which is useful in predicting outcome.
Feras Zaiem, Rada Jerbi, Omar Albanyan, Jordyn Puccio, Zyad Kafri, Jay Yang, Ali M Gabali   +6 more
doaj   +1 more source

An Expanding Job Description for Bcl6 [PDF]

Journal of Molecular Cell Biology, 2009
B cell lymphoma/leukemia gene 6 (Bcl6) is well known as a master regulator of germinal center (GC) B cell differentiation. Now, three new publications demonstrate that Bcl6 also plays a second role in GC response, in that it is both required and sufficient to drive the differentiation of T follicular helper cells.
Enguang, Bi, B Hilda, Ye
openaire   +2 more sources