Biomolecules, 2019 The brain-derived neurotrophic factor (BDNF) was initially considered to be neuron-specific. Meanwhile, this neurotrophin is peripherally also secreted by skeletal muscle cells and increases due to exercise.
Marie-Lena Schmalhofer +19 more
doaj +1 more source
Trace Elements Genetics: A Potential Role in Treatment‐Resistant Major Psychoses and Related Traits?
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Trace elements are pivotal to key biological processes, with possible effects on psychopathology. We investigated the hypothesis of shared genetic factors between trace elements levels, treatment resistance and related traits. We used genome‐wide summary statistics for trace elements blood concentration, treatment‐resistant depression (TRD ...
Chiara Fabbri +6 more
wiley +1 more source
Relationship of BDNF SNP type and gender disparities in the STEM workforce
, 2021 Forbes, Chad E.The brain derived neurotrophic factor (BDNF) gene encodes for the BDNF protein that is essential for the development of the central nervous system.
Hadley, Lydia G.
core +1 more source
Extending the ATP9A‐Related Phenotypic Spectrum: Indication of Schizophrenia Susceptibility
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT ATP9A, which belongs to the P4‐ATPase family of proteins, is involved in the efficient transport of vesicles from the Golgi apparatus to the plasma membrane, as well as the release of extracellular vesicles from human cells. In 2021, a loss‐of‐function variant of this gene was identified as being associated with a recessive neurodevelopmental ...
Camille Verebi +10 more
wiley +1 more source
An Investigation of the Role of Sex Difference in the Effect of Fluoxetine on Behavioral and Biochemical Changes in Male and Female Rats Exposed to Stress [PDF]
Journal of Mazandaran University of Medical SciencesBackground and purpose: Unpredictable stressors cause changes in behavioral parameters such as motor and exploratory behaviors, feeding, and sexual and anxiety behaviors. Stress leads to the release of corticosteroids and, as a result, causes dysfunction
Moslem Mohammadi +5 more
doaj
A terapia combinada de exercício físico e creatina induz efeito tipo-antidepressivo e aumento de BDNF no hipocampo de camundongos [PDF]
, 2014 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Bioquímica, Florianópolis, 2014.Os tratamentos farmacológicos disponíveis para a depressão demandam semanas para surtir efeito e ...
Oliveira, Ágatha
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Characteristics of the BDNF Val66Met polymorphism in competitive swimmers and judo athletes [PDF]
, 2020 Studies have demonstrated that motivation, aggression, excitation intensity, competitive spirit, and tolerance to psychological stress are included in major psychological factors affecting the performance of athletes.
Ohishi, Kenji +9 more
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Long-term gene therapy causes transgene-specific changes in the morphology of regenerating retinal ganglion cells [PDF]
, 2012 Recombinant adeno-associated viral (rAAV) vectors can be used to introduce neurotrophic genes into injured CNS neurons, promoting survival and axonal regeneration.
Rodger Jennifer +14 more
core +2 more sources
Animal Models and Experimental Medicine, EarlyView.Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley +1 more source
LOCAL SUPPLEMENTATION OF BRAINDERIVED NEUROTROPHIC FACTOR FOR THE TREATMENT OF NEURONAL DAMAGE. [PDF]
, 2010 The importance of nerve growth factors, especially brain-derived neurotrophic factor (BDNF) in the regulation of neuronal survival and plastic changes in morphology and function has been increasingly studied during the recent years.
Su, Tao
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