Results 101 to 110 of about 220,963 (383)

A polymorphism associated with depressive disorders differentially regulates brain derived neurotrophic factor promoter IV activity [PDF]

, 2012
PMCID: PMC3712170Peer reviewedPublisher ...
Aid, Alasdair MacKenzie, Almeida, Alonso, Alvarez-Buylla, Barrett, Bearden, Bearden, Benjamin Hing, Bernier, Boukhaddaoui, Chen, Chen, Chung, Cornwell, Corvol, Cunha, Davidson, Davidson, De Gobbi, Dijkhuizen, Dixon, Dunham, Dwivedi, Dwivedi, Eriksson, Gaunitz, Gerome Breen, Gould, Hacking, Hamilton, Hansen, Hayashi, He, Heckert, Hedges, Hermann, Hofer, Jaworski, John Quinn, Juhasz, Kauer-Sant'Anna, Kohara, Koppel, Koppel, Korte, Kumar, Kumar, Lettice, Lettice, Liu, Ma, Machado, Machado, MacNicol, Marrisa Lear, Martinez-Aran, Martinowich, Marty, McDowell, Miller, Miller, Murgatroyd, Nielsen, Ovcharenko, Peter McGuffin, Poitras, Pruunsild, Pruunsild, Rockman, Rossi, Sakata, Sanderson, Savitz, Sawada, Scharfman, Scott Davidson, Seale, Shanley, Sharma, Siciliano, Sturm, Sun, Tabuchi, Taliaz, Tao, Tao, Thompson, Tolwani, Weniger, Yan, Yasuda   +91 more
core   +1 more source

Locating BDNF [PDF]

Nature Reviews Neuroscience, 2012
The low levels of endogenous brain-derived neurotrophic factor (BDNF) in the mature nervous system have hindered attempts to determine the subcellular localization of this peptide. Through use of confocal and immunogold electron microscopy, Dieni et al.
openaire   +2 more sources

BDNF and Pro-BDNF in Amyotrophic Lateral Sclerosis: A New Perspective for Biomarkers of Neurodegeneration

Brain Sciences, 2022
Amyotrophic Lateral Sclerosis (ALS) is characterized by the progressive degeneration of upper or lower motor neurons, leading to muscle wasting and paralysis, resulting in respiratory failure and death. The precise ALS aetiology is poorly understood, mainly due to clinical and genetic heterogeneity.
Giulia Riolo, Claudia Ricci, Nicoletta De Angelis, Carlotta Marzocchi, Gisella Guerrera, Giovanna Borsellino, Fabio Giannini, Stefania Battistini   +7 more
openaire   +5 more sources

Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum, Abhirami Thumsi, Kara Dunn, Lindsey Druschel, Sierra Chimene, David Flores Prieto, Amberlyn Simmons, Shivani Mantri, Arezoo Esrafili, Srivatsan J. Swaminathan, Mytreyi Trivedi, Shreya Anandan, Crystal Willingham, Alondra Davila, Sahil Inamdar, Joslyn L. Mangal, Abhirami P. Suresh, Niveda M. Kasthuri, Madan Mohan Chandra Sekhar Jaggarapu, Nicole Appel, Taravat Khodaei, Nathan D. Ng, Alison Sundem, Sanmoy Pathak, George Bjorklund, Jason Newbern, Jeffrey Capadona, Sarah E. Stabenfeldt, Abhinav P. Acharya   +28 more
wiley   +1 more source

Astrocyte morphogenesis is dependent on BDNF signaling via astrocytic TrkB.T1

eLife, 2019
Brain-derived neurotrophic factor (BDNF) is a critical growth factor involved in the maturation of the CNS, including neuronal morphology and synapse refinement.
Leanne M. Holt, Raymundo Hernandez, Natasha L. Pacheco, Beatriz Torres Ceja, Muhannah Hossain, M. Olsen   +5 more
semanticscholar   +1 more source

Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain

Advanced Materials, EarlyView.
A novel carbon quantum dots‐dissolvable microneedle, CQDs‐dMN system, enables painless delivery and real‐time tracking of HSV‐1. The HSV‐1 is labeled with fluorescent CQDs and delivered to the skin dermis, minimizing damage compared to traditional methods.
Yaxiu Feng, Xiong Wang, Cien Chen, Di Wang, Changshun Hou, Yiran Wang, Huan Hu, Peiran Chen, LeiYing Qin, Qianya Wan, Xi Yao, Ming‐Liang He   +11 more
wiley   +1 more source

اثر پروبیوتیک لاکتوباسیلوس پاراکازئی بر بیان ژن BDNF در استریاتوم مغز موش‌های صحراییِ مدل پارکینسونی القا شده توسط ۶- هیدروکسی دوپامین [PDF]

Majallah-i Dānishkadah-i Pizishkī-i Dānishgāh-i ̒ Ulūm-i Pizishkī-i Mashhad.
زمینه و هدف: در بیماری پارکینسون از بین رفتن نورون‌های دوپامینرژیک در هسته‌های قاعده‌ای باعث تحلیل عصبی می‌شود. با نظر به نقش مثبت فاکتور نوروتروفیک مشتق از مغز BDNF در بیماری‌های تحلیل‌برنده‌ی عصبی و ویژگی‌های محافظتی پروبیوتیک‌ها در مقابل عوامل موثر در
فروزنده درویش‌زاده
doaj   +1 more source

Using Crosslinked Hyaluronic Acid (HA) and Collagen Scaffolds with Sustained Brain-Derived Neurotrophic Factor (BDNF) Release for Post-SCI Nerve Regeneration [PDF]

, 2018
Traumatic events resulting in spinal cord injuries (SCIs) often leave people paralyzed or with partial loss of motor function. The physical disabilities arising from traumatic events prevent people from functioning at the same level as pre-injury.
Doshi, Panth
core   +1 more source

Bioengineered Models of Nerve Regeneration

Advanced Materials Technologies, EarlyView.
Bioengineered nerve regeneration platforms ranging from patterned cell cultures and hydrogels to fibrous scaffolds and microfluidic systems are reviewed, highlighting the complex cellular and biochemical environments essential for nerve repair. Challenges associated with these platforms, such as balancing complexity with throughput and the need for ...
Madalynn Jade Thompson, John Paul Frampton   +1 more
wiley   +1 more source

Mechanisms That Modulate and Diversify BDNF Functions: Implications for Hippocampal Synaptic Plasticity

Frontiers in Cellular Neuroscience, 2019
Brain-derived neurotrophic factor (BDNF) is a neurotrophin that has pleiotropic effects on neuronal morphology and synaptic plasticity that underlie hippocampal circuit development and cognition.
Ana Paula De Vincenti, A. Ríos, G. Paratcha, F. Ledda   +3 more
semanticscholar   +1 more source