Results 41 to 50 of about 220,963 (383)
Lactate and BDNF: Key Mediators of Exercise Induced Neuroplasticity?
Accumulating evidence from animal and human studies supports the notion that physical exercise can enhance neuroplasticity and thus reduce the risk of several neurodegenerative diseases (e.g., dementia). However, the underlying neurobiological mechanisms
P. Müller+3 more
semanticscholar +1 more source
BDNF/TrkB axis activation promotes epithelial-mesenchymal transition in idiopathic pulmonary fibrosis [PDF]
Background: Neurotrophins (NT) belongs to a family of growth factors which promotes neurons survival and differentiation. Increasing evidence show that NT and their receptor are expressed in lung tissues suggesting a possible role in lung health and ...
Bruno, Pierdonato+8 more
core +1 more source
Regulation of BDNF-TrkB Signaling and Potential Therapeutic Strategies for Parkinson’s Disease
Brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin-related kinase receptor type B (TrkB) are widely distributed in multiple regions of the human brain.
W. Jin
semanticscholar +1 more source
Neuroscience-informed Auditory Training in Schizophrenia: A Final Report of the Effects on Cognition and Serum Brain-Derived Neurotrophic Factor. [PDF]
ObjectiveWe previously reported the interim effects in a per protocol analysis of a randomized controlled trial of an innovative neuroscience-informed computerized cognitive training approach in schizophrenia.
Fisher, Melissa+3 more
core +2 more sources
Xiao-Ling Li,1,* Hua Liu,2,* Shu-Han Liu,2 Yong Cheng,2,3 Guo-Jun Xie1 1The Third People’s Hospital of Foshan, Foshan, People’s Republic of China; 2Center on Translational Neuroscience, School of Pharmacy, Minzu University of China, Beijing ...
Li XL, Liu H, Liu SH, Cheng Y, Xie GJ
doaj
Enriched environment reduces glioma growth through immune and non-immune mechanisms in mice [PDF]
Mice exposed to standard (SE) or enriched environment (EE) were transplanted with murine or human glioma cells and differences in tumour development were evaluated.
BENIGNI, GIORGIA+13 more
core +1 more source
Neurotrophins: A Ticket to Ride for BDNF [PDF]
The secretion of BDNF from neurons is under activity-dependent control: this is crucial for the formation of appropriate synaptic connections during development and for learning and memory in adults. New evidence shows that interaction between a motif in the tertiary structure of BDNF and the sorting receptor carboxypeptidase E directs this ...
Kerrie L. Thomas, Alun M. Davies
openaire +3 more sources
The immediate early gene Egr3 Is required for hippocampal induction of Bdnf by electroconvulsive stimulation [PDF]
Early growth response 3 (Egr3) is an immediate early gene (IEG) that is regulated downstream of a cascade of genes associated with risk for psychiatric disorders, and dysfunction of Egr3 itself has been implicated in schizophrenia, bipolar disorder, and ...
Brunwasser, Samuel J+6 more
core +2 more sources
Developing with BDNF: A Moving Experience [PDF]
During development, newly born neurons migrate away from their initial birth sites to their final positions in the mature brain. The neurotrophin BDNF has been shown to regulate the migration of granule cells in the cerebellum. The cellular mechanisms that mediate this chemotactic response have not been resolved.
Freda D. Miller, David L. Kaplan
openaire +3 more sources
Patients with interstitial cystitis/bladder pain syndrome (IC/BPS) often grieve over a low quality of life brought about by chronic pain. In our previous studies, we determined that neuroinflammation of the spinal dorsal horn (SDH) was associated with ...
Honglu Ding+11 more
semanticscholar +1 more source