Results 41 to 50 of about 220,963 (383)

Lactate and BDNF: Key Mediators of Exercise Induced Neuroplasticity?

open access: yesJournal of Clinical Medicine, 2020
Accumulating evidence from animal and human studies supports the notion that physical exercise can enhance neuroplasticity and thus reduce the risk of several neurodegenerative diseases (e.g., dementia). However, the underlying neurobiological mechanisms
P. Müller   +3 more
semanticscholar   +1 more source

BDNF/TrkB axis activation promotes epithelial-mesenchymal transition in idiopathic pulmonary fibrosis [PDF]

open access: yes, 2017
Background: Neurotrophins (NT) belongs to a family of growth factors which promotes neurons survival and differentiation. Increasing evidence show that NT and their receptor are expressed in lung tissues suggesting a possible role in lung health and ...
Bruno, Pierdonato   +8 more
core   +1 more source

Regulation of BDNF-TrkB Signaling and Potential Therapeutic Strategies for Parkinson’s Disease

open access: yesJournal of Clinical Medicine, 2020
Brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin-related kinase receptor type B (TrkB) are widely distributed in multiple regions of the human brain.
W. Jin
semanticscholar   +1 more source

Neuroscience-informed Auditory Training in Schizophrenia: A Final Report of the Effects on Cognition and Serum Brain-Derived Neurotrophic Factor. [PDF]

open access: yes, 2015
ObjectiveWe previously reported the interim effects in a per protocol analysis of a randomized controlled trial of an innovative neuroscience-informed computerized cognitive training approach in schizophrenia.
Fisher, Melissa   +3 more
core   +2 more sources

Intranasal Administration of Brain-Derived Neurotrophic Factor Rescues Depressive-Like Phenotypes in Chronic Unpredictable Mild Stress Mice

open access: yesNeuropsychiatric Disease and Treatment, 2022
Xiao-Ling Li,1,* Hua Liu,2,* Shu-Han Liu,2 Yong Cheng,2,3 Guo-Jun Xie1 1The Third People’s Hospital of Foshan, Foshan, People’s Republic of China; 2Center on Translational Neuroscience, School of Pharmacy, Minzu University of China, Beijing ...
Li XL, Liu H, Liu SH, Cheng Y, Xie GJ
doaj  

Enriched environment reduces glioma growth through immune and non-immune mechanisms in mice [PDF]

open access: yes, 2015
Mice exposed to standard (SE) or enriched environment (EE) were transplanted with murine or human glioma cells and differences in tumour development were evaluated.
BENIGNI, GIORGIA   +13 more
core   +1 more source

Neurotrophins: A Ticket to Ride for BDNF [PDF]

open access: yesCurrent Biology, 2005
The secretion of BDNF from neurons is under activity-dependent control: this is crucial for the formation of appropriate synaptic connections during development and for learning and memory in adults. New evidence shows that interaction between a motif in the tertiary structure of BDNF and the sorting receptor carboxypeptidase E directs this ...
Kerrie L. Thomas, Alun M. Davies
openaire   +3 more sources

The immediate early gene Egr3 Is required for hippocampal induction of Bdnf by electroconvulsive stimulation [PDF]

open access: yes, 2018
Early growth response 3 (Egr3) is an immediate early gene (IEG) that is regulated downstream of a cascade of genes associated with risk for psychiatric disorders, and dysfunction of Egr3 itself has been implicated in schizophrenia, bipolar disorder, and ...
Brunwasser, Samuel J   +6 more
core   +2 more sources

Developing with BDNF: A Moving Experience [PDF]

open access: yesNeuron, 2007
During development, newly born neurons migrate away from their initial birth sites to their final positions in the mature brain. The neurotrophin BDNF has been shown to regulate the migration of granule cells in the cerebellum. The cellular mechanisms that mediate this chemotactic response have not been resolved.
Freda D. Miller, David L. Kaplan
openaire   +3 more sources

BDNF promotes activation of astrocytes and microglia contributing to neuroinflammation and mechanical allodynia in cyclophosphamide-induced cystitis

open access: yesJournal of Neuroinflammation, 2020
Patients with interstitial cystitis/bladder pain syndrome (IC/BPS) often grieve over a low quality of life brought about by chronic pain. In our previous studies, we determined that neuroinflammation of the spinal dorsal horn (SDH) was associated with ...
Honglu Ding   +11 more
semanticscholar   +1 more source

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