Results 81 to 90 of about 220,963 (383)
Platelets, 2017 Cigarette smoke (CS) activates platelets, promotes vascular dysfunction, and enhances Tissue Factor (TF) expression in blood monocytes favoring pro-thrombotic states.
Patrizia Amadio +5 more
doaj +1 more source
The effect of aerobic exercise along with living in enriched environment on spatial memory and brain-derived neurotrophic factor in the Hippocampal tissue of Elderly female Wistar rats with Alzheimer's disease [PDF]
فیزیولوژی ورزش و فعالیت بدنیBackground and Purpose: The effect of physical activity and living in enriched environment on some cognitive mechanisms in Alzheimer's disease (AD) is not yet well understood.
Mozhgan Mozhgan Abdullahzadeh Nobejari +2 more
doaj +1 more source
Фармакокинетика и Фармакодинамика, 2020 The present work was to study the GSB-106 effect on the immobility behavior of mice Balb/c in the Porsolt test. GSB-106 was administered sub-chronically and chronically intraperitoneal in dose 1 mg/kg.
A. V. Tallerova +4 more
doaj +1 more source
Valutazione dei livelli di BDNF ematico in uno studio di follow-up su pazienti con depressione maggiore [PDF]
, 2005 Il fattore neurotrofico cervello-derivato (BDNF) è, tra i membri della famiglia delle neurotrofine, quello che mostra l'espressione più diffusa nel cervello del mammifero adulto e in fase di sviluppo.
Scatena, Alessia
core
Neurotrophins Role in Depression Neurobiology: A Review of Basic and Clinical Evidence [PDF]
, 2011 Depression is a neuropsychiatric disorder affecting a huge percentage of the active population especially in developed countries. Research has devoted much of its attention to this problematic and many drugs have been developed and are currently ...
Berrocoso Domínguez, Esther María +4 more
core +4 more sources
Machine Learning Guided Design of Nerve‐On‐A‐Chip Platforms with Promoted Neurite Outgrowth
Advanced Functional Materials, EarlyView.Compared to labor‐intensive trial‐and‐error experimentation, a machine learning (ML)‐guided workflow, incorporating cell viability assays, data augmentation, ensemble modeling, and model interpretation, is developed to accelerate nerve‐on‐a‐chip optimization and uncover data‐driven design principles.
Tsai‐Chun Chung +8 more
wiley +1 more source
Drug Design, Development and Therapy, 2020 Yao Yao,* Xuesong Wang,* Jin Gao Department of Anesthesiology, Xiangyang Central Hospital, Affiliated Hospital of Hubei College of Arts and Science, Xiangyang 441021, Hubei, People’s Republic of China*These authors contributed equally to this ...
Yao Y, Wang X, Gao J
doaj
Genetically engineered mesenchymal stem cells as a proposed therapeutic for Huntington's disease. [PDF]
, 2011 There is much interest in the use of mesenchymal stem cells/marrow stromal cells (MSC) to treat neurodegenerative disorders, in particular those that are fatal and difficult to treat, such as Huntington's disease.
Annett, Geralyn +14 more
core +3 more sources
Advanced Functional Materials, EarlyView.Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu +7 more
wiley +1 more source
Modulation of neurotrophic signaling pathways by polyphenols [PDF]
, 2015 Polyphenols are an important class of phytochemicals, and several lines of evidence have demonstrated their beneficial effects in the context of a number of pathologies including neurodegenerative disorders such as Alzheimer's and Parkinson's disease. In
Firuzi, Omidreza +3 more
core +1 more source